Art

J-GLOBAL ID：201802285387400566   Reference number：18A0530538

Development of a highly sensitive in vitro system to detect and discriminate between vitamin D receptor agonists and antagonists based on split-luciferase technique

検出と識別するための高感度in vitro系ビタミンD受容体作動薬の開発とルシフェラーゼ法をベースにしたきっ抗物質【Powered by NICT】

Author (5)： Mano Hiroki (Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan) ,  Ikushiro Shinichi (Department of Biotechnology, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan) ,  Saito Nozomi (Faculty of Pharmaceutical Sciences, Teikyo University, Itabashi, Tokyo 173-8605 Japan) ,  Kittaka Atsushi (Faculty of Pharmaceutical Sciences, Teikyo University, Itabashi, Tokyo 173-8605 Japan) ,  Sakaki Toshiyuki (Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan)
Material： Journal of Steroid Biochemistry & Molecular Biology  (Journal of Steroid Biochemistry and Molecular Biology)
Volume： 178  Page： 55-59  Publication year： 2018 
JST Material Number： C0595A  ISSN： 0960-0760  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Split-luciferase techniques ar...

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Thesaurus term： *vitamin D ,  serum concentration ,  *vitamin ,  biosensor ,  *antagonism ,  *high sensitivity ,  hormone ,  *vitamin D receptor ,  biological activity ,  therapy ,  protein ,  *luciferase ,  binding site
Semi thesaurus term： 蛋白質間相互作用 ,  *アゴニスト , 【Automatic Indexing@JST】

Author keywords (5)： Vitamin D ,  Vitamin D receptor ,  Bioluminescent sensor ,  Split-luciferase ,  Screening system

JST classification (1)： Vitamin D  (EB07050H)

Terms in the title (6)： 識別 ,  高感度 ,  ビタミンD受容体 ,  作動薬 ,  開発 ,  ルシフェラーゼ