Art

J-GLOBAL ID：201802286270111857   Reference number：18A1002026

Transcription factor specificity protein 1 modulates TGFβ1/Smad signaling to negatively regulate SIGIRR expression by human M1 macrophages stimulated with substance P

転写因子特異性蛋白質1はサブスタンスPで刺激されたヒトM1マクロファージによるsigirR発現を負に調節するためにTGF-β1/Smadシグナル伝達を調節する【JST・京大機械翻訳】

Author (7)： Yamaguchi Rui (Graduate School of Medical Science, Kumamoto Health Science University, Kitaku Izumi-machi 325, Kumamoto 861-5598, Japan) ,  Sakamoto Arisa (Graduate School of Medical Science, Kumamoto Health Science University, Kitaku Izumi-machi 325, Kumamoto 861-5598, Japan) ,  Yamaguchi Reona (Department of Neuroscience, Graduate School of Medicine, Kyoto University, Yoshida-konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan) ,  Haraguchi Misa (Graduate School of Medical Science, Kumamoto Health Science University, Kitaku Izumi-machi 325, Kumamoto 861-5598, Japan) ,  Narahara Shinji (Graduate School of Medical Science, Kumamoto Health Science University, Kitaku Izumi-machi 325, Kumamoto 861-5598, Japan) ,  Sugiuchi Hiroyuki (Graduate School of Medical Science, Kumamoto Health Science University, Kitaku Izumi-machi 325, Kumamoto 861-5598, Japan) ,  Yamaguchi Yasuo (Graduate School of Medical Science, Kumamoto Health Science University, Kitaku Izumi-machi 325, Kumamoto 861-5598, Japan)
Material： Cytokine
Volume： 108  Page： 24-36  Publication year： 2018 
JST Material Number： W0144A  ISSN： 1043-4666  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The stimuli inducing expressio...

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Thesaurus term： *transcription factor ,  Transfection ,  siRNA ,  protein synthesis ,  MAP kinase ,  *macrophage ,  lipopolysaccharide ,  Gene Silencing ,  *human ,  receptor ,  Up-Regulation ,  interleukin 1 ,  Sp1 Transcription Factor ,  *Smad Proteins
Semi thesaurus term： アゴニスト , 【Automatic Indexing@JST】

Author keywords (5)： Neurokinin-1 receptor ,  SIGIRR ,  Specificity protein 1 ,  Substance P ,  TGFβ1

JST classification (1)： Cytokines  (EB08090G)

Terms in the title (12)： 転写因子 ,  特異性 ,  蛋白質 ,  サブスタンスP ,  刺激 ,  ヒト ,  M1マクロファージ ,  発現 ,  調節 ,  TGF-β1 ,  SMAD ,  シグナル伝達