Art

J-GLOBAL ID：201802286836442080   Reference number：18A0174681

A case of anti-MDA5-positive rapidly progressive interstitial lung disease in a patient with clinically amyopathic dermatomyositis ameliorated by rituximab, in addition to standard immunosuppressive treatment

標準的免疫抑制療法に加えたリツキシマブによって緩和された臨床的に無症候性の皮膚筋炎の患者における抗MDA5陽性な急速に進行性の間質性肺疾患の症例

Author (18)： KOICHI Yamaguchi (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  AYA Yamaguchi (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  MEGUMI Uchida (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  SHUNICHI Kono (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  MASAFUMI Suzuki (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  HIROAKI Masubuchi (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  MASAHIKO Kanbe (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  SHINSUKE Kitahara (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  MANABU Ueno (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  KENICHIRO Hara (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  FUMIAKI Aoki (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  NOZOMI Aoki (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  TOSHITAKA Maeno (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  MASAYOSHI Yamanaka (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  CHIKAKO Kishi (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  YOSHINAO Muro (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN) ,  TATSUO Suga (Gunma Univ. Graduate School of Medicine, Maebashi, JPN) ,  MASAHIKO Kurabayashi (Gunma Univ. Graduate School of Medicine, Maebashi, JPN)
Material： Modern Rheumatology  (Mod Rheumatol)
Volume： 27  Issue： 3  Page： 536-540  Publication year： May. 2017 
JST Material Number： L5142A  ISSN： 1439-7595  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *Rituximab ,...

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JST classification (2)： Treatment for immunologic diseases,allergic diseases.  (GD04030Y) ,  Drug therapy(=pharmacotherapy)for respiratory system diseases  (GI05020J)

Substance index (3)： Cyclophosphamid ,  Tacrolimus ,  Prednisolone

Reference (20)：

• Gerami P, Walling HW, Lewis J, Doughty L, Sontheimer RD. A systematic review of adult-onset clinically-amyopathic dermatomyositis (syn. dermatomyositis sine myositis): a missing link within the spectrum of the idiopathic inflammatory myopathies. J Am Acad Dermatol. 2006;54(4):597-613.
• Tokiyama K, Tagawa H, Yokota E, Nagasawa K, Kusaba T, Tsuda Y, Niho Y. Two cases of amyopathic dermatomyositis with fatal rapidly progressive interstitial pneumonitis. Ryumachi. 1990;30(3):204-11.
• Nakashima R, Imura Y, Kobayashi S, Yukawa N, Yoshifuji H, Nojima T, et al. The RIG-I-like receptor IFIH1/MDA5 is a dermatomyositis-specific autoantigen identified by the anti-CADM-140 antibody. Rheumatology (Oxford). 2010;49(3):433-40.
• Gono T, Sato S, Kawaguchi Y, Kuwana M, Hanaoka M, Katsumata Y, et al. Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis. Rheumatology(Oxford). 2012;51(9):1563-70.
• Kotani T, Takeuchi T, Makino S, Hata K, Yoshida S, Nagai K, et al. Combination with corticosteroids and cyclosporin-A improves pulmonary function test results and chest HRCT findings in dermatomyositis patients with acute/subacute interstitial pneumonia. Clin Rheumatol. 2011;30(8):1021-28.

Terms in the title (11)： 標準 ,  免疫抑制療法 ,  リツキシマブ ,  緩和 ,  臨床 ,  症候 ,  皮膚筋炎 ,  患者 ,  MDA5 ,  間質性肺疾患 ,  症例