Art

J-GLOBAL ID：201802287450340768   Reference number：18A0314979

SYNTHESIS OF DIBROMO COMPOUNDS CONTAINING 2,6-DIOXABICYCLO[3.1.1]HEPTANE SIMILAR TO CORE MOIETY OF THROMBOXANE A₂

トロンボキサンA₂のコア部分と類似した2,6-ジオキサビシクロ[3.1.1]ヘプタンを有するジブロモ化合物の合成

Author (3)： NOKURA Yoshihiko (Nagoya Univ., Nagoya) ,  NAKAZAKI Atsuo (Nagoya Univ., Nagoya) ,  NISHIKAWA Toshio (Nagoya Univ., Nagoya)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 96  Issue： 1  Page： 127-136  Publication year： Jan. 01, 2018 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： asymmetric synthesis ,  *cyclic ether ,  *bridged compound ,  aliphatic bromine compound ,  acetal ,  unsaturated sugar ,  bromination ,  *cyclization reaction ,  diene ,  oxygen heterocyclic compound ,  unsaturated alcohol ,  unsaturated carboxylic acid ,  thromboxane
Semi thesaurus term： tetrahydropyran derivative

JST classification (2)： Monosaccharides  (CF10052H) ,  Pyranes  (CF07092R)

Substance index (9)： (1R,5R)-3α-(Benzyloxymethyl)-4β-(benzyloxy)-7,7-dibromo-2,6-dioxabicyclo[3.1.1]heptane ,  (1S,5S)-3α-(Benzyloxymethyl)-4β-(benzyloxy)-7,7-dibromo-2,6-dioxabicyclo[3.1.1]heptane ,  (2R)-2α,3,3-Tribromo-5α-(benzyloxy)-6β-(benzyloxymethyl)tetrahydro-2H-pyran-4α-ol ,  (2R)-2α,3,3-Tribromo-5α-(benzyloxy)-6β-(benzyloxymethyl)tetrahydro-2H-pyran-4β-ol ,  2α-[(Benzyloxy)methyl]-3β-(benzyloxy)-2H-pyran-4(3H)-one ,  (2R)-2α-(Benzyloxymethyl)-3β-(benzyloxy)-5-bromo-3,4-dihydro-2H-pyran-4α-ol ,  (2R)-2α-(Benzyloxymethyl)-3β-(benzyloxy)-5-bromo-3,4-dihydro-2H-pyran-4β-ol ,  Tri-O-acetyl-D-glucal ,  Thromboxane A2

Reference (11)：

• (a) A. Nakazaki, Y. Ishikawa, Y. Sawayama, M. Yotsu-Yamashita, and T. Nishikawa, Org. Biomol. Chem., 2014, 12, 53; (b) A. Nakazaki, Y. Nakane, Y. Ishikawa, M. Yotsu-Yamashita, and T. Nishikawa, Org. Biomol. Chem., 2016, 14, 5304.
• A. Nakazaki, Y. Nakane, Y. Ishikawa, and T. Nishikawa, Heterocycles, 2015, 91, 1157.
• (a) Y. Sawayama and T. Nishikawa, Synlett, 2011, 651; (b) Y. Sawayama and T. Nishikawa, J. Synth. Org. Chem. Jpn., 2012, 70, 1178; (c) Y. Sawayama and T. Nishikawa, Angew. Chem. Int. Ed., 2011, 50, 7176.
• E. M. Carreira and T. C. Fessard, Chem. Rev., 2014, 114, 8257.
• (a) S. S. Bhagwat, P. R. Hamann, and W. C. Still, J. Am. Chem. Soc., 1985, 107, 6372; (b) S. S. Bhagwat, P. R. Hamann, W. C. Still, S. Bunting, and F. A. Fitzpatrick, Nature, 1985, 315, 511.

Terms in the title (4)： トロンボキサンA2 ,  コア ,  類似 ,  ヘプタン