Art

J-GLOBAL ID：201802288308616327   Reference number：18A0958019

Effects of mismatches distant from the target position on gene correction with a 5′-tailed duplex

5′-尾二本鎖による遺伝子修復に対する標的場所からの距離のミスマッチの影響

Author (11)： Suzuki Tetsuya (Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan) ,  Suzuki Tetsuya (School of Pharmaceutical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan) ,  Yanai Yuri (School of Pharmaceutical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan) ,  Nishigaki Natsuki (Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan) ,  Nishigaki Natsuki (Graduate School of Science and Engineering, Ehime University, 2-5 Bunkyo-cho, Matsuyama 790-8577, Japan) ,  Nakatsu Yoshimichi (Faculty of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan) ,  Tsuzuki Teruhisa (Faculty of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan) ,  Tsuzuki Teruhisa (Advanced Science Research Center, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan) ,  Kamiya Hiroyuki (Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan) ,  Kamiya Hiroyuki (School of Pharmaceutical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan) ,  Kamiya Hiroyuki (Graduate School of Science and Engineering, Ehime University, 2-5 Bunkyo-cho, Matsuyama 790-8577, Japan)
Material： Journal of Bioscience and Bioengineering
Volume： 125  Issue： 5  Page： 619-623  Publication year： May. 2018 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *mutation ,...
Semi thesaurus term： *substitution mutation ,...

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Author keywords (6)： Gene correction ,  Nucleotide sequence conversion ,  5′-tailed duplex ,  Frameshift mismatch ,  Base-base mismatch ,  rpsL gene

JST classification (2)： Genetic variation  (EC01030Y) ,  Gene manipulation  (EC02050B)

Reference (26)：

• Gruenert, D. C., Bruscia, E., Novelli, G., Colosimo, A., Dallapiccola, B., Sangiuolo, F., and Goncz, K. K.: Sequence-specific modification of genomic DNA by small DNA fragments, J. Clin. Invest., 112, 637-641 (2003).
• Sangiuolo, F., Scaldaferri, M. L., Filareto, A., Spitalieri, P., Guerra, L., Favia, M., Caroppo, R., Mango, R., Bruscia, E., Gruenert, D. C., and other 3 authors: Cftr gene targeting in mouse embryonic stem cells mediated by small fragment homologous replacement (SFHR), Front. Biosci., 13, 2989-2999 (2008).
• Richardson, P. D., Augustin, L. B., Kren, B. T., and Steer, C. J.: Gene repair and transposon-mediated gene therapy, Stem Cells, 20, 105-118 (2002).
• de Semir, D. and Aran, J. M.: Targeted gene repair: the ups and downs of a promising gene therapy approach, Curr. Gene Ther., 6, 481-504 (2006).
• Bertoni, C.: Oligonucleotide-mediated gene editing for neuromuscular disorders, Acta Myol., 24, 194-201 (2005).

Terms in the title (5)： 尾 ,  遺伝子 ,  修復 ,  標的 ,  ミスマッチ