Art

J-GLOBAL ID：201802288318970943   Reference number：18A1488836

Anti-inflammatory properties of cilostazol: Its interruption of DNA binding activity of NF-κB from the Toll-like receptor signaling pathways

シロスタゾールの抗炎症特性:Toll様受容体シグナル伝達経路からのNF-κBのDNA結合活性の中断【JST・京大機械翻訳】

Author (6)： Sakamoto Takuya (Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan) ,  Ohashi Wakana (Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan) ,  Tomita Kengo (Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan) ,  Hattori Kohshi (Department of Anesthesiology and Pain Relief Center, The University of Tokyo Hospital, Tokyo, Japan) ,  Matsuda Naoyuki (Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Hattori Yuichi (Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan)
Material： International Immunopharmacology  (Int Immunopharmacol)
Volume： 62  Page： 120-131  Publication year： 2018 
JST Material Number： T0026B  ISSN： 1567-5769  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Cilostazol, a selective inhibi...

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Thesaurus term： phosphorylation ,  macrophage ,  ischemia ,  oral administration ,  lipopolysaccharide ,  interleukin 6 ,  *NF-kappaB ,  inflammatory cytokine ,  luciferase ,  *Toll like receptor ,  *anti-inflammatory action ,  MAP kinase ,  alicyclic compound ,  lactam ,  phenol ether ,  polynuclear aromatic compound
Semi thesaurus term： p65 ,  Toll様受容体4 , 【Automatic Indexing@JST】

Author keywords (4)： Lipopolysaccharide ,  NF-κB ,  Pro-inflammatory cytokines ,  Tissue injury

JST classification (2)： Basic research of anti-inflammatory drugs  (GW15010T) ,  Biophylaxis and immune systems in general  (ED01010F)

Substance index (1)： Cilostazol

Terms in the title (8)： シロスタゾール ,  抗炎症 ,  Toll様受容体 ,  シグナル伝達経路 ,  NF-κB ,  DNA結合 ,  活性 ,  中断