Art

J-GLOBAL ID：201802288774188187   Reference number：18A0584124

Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids

ヒトのiPSC-由来後腸前駆細胞は成形腸と肝臓オルガノイドの拡張性と可能である【Powered by NICT】

Author (15)： Zhang Ran-Ran (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Zhang Ran-Ran (Division of Gastroenterology, Hepatology & Nutrition, Developmental Biology, Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229-3039, USA) ,  Koido Masaru (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Tadokoro Tomomi (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Ouchi Rie (Division of Gastroenterology, Hepatology & Nutrition, Developmental Biology, Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229-3039, USA) ,  Matsuno Tatsuya (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Ueno Yasuharu (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Sekine Keisuke (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Takebe Takanori (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Takebe Takanori (Division of Gastroenterology, Hepatology & Nutrition, Developmental Biology, Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229-3039, USA) ,  Takebe Takanori (Advanced Medical Research Center, Yokohama City University, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Takebe Takanori (PRESTO, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan) ,  Takebe Takanori (Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA) ,  Taniguchi Hideki (Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Kanazawa-ku 3-9, Yokohama, Kanagawa 236-0004, Japan) ,  Taniguchi Hideki (Division of Gastroenterology, Hepatology & Nutrition, Developmental Biology, Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229-3039, USA)
Material： Stem Cell Reports
Volume： 10  Issue： 3  Page： 780-793  Publication year： 2018 
JST Material Number： W3132A  ISSN： 2213-6711  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Early endoderm progenitors nat...

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Thesaurus term： differentiation (biology) ,  induced pluripotent stem cell ,  Teratoma ,  clone ,  *human ,  robustness ,  reproducibility ,  pluripotent stem cell ,  gene introduction ,  therapy ,  modeling ,  endoderm ,  Transcriptome analysis ,  *Organoid ,  *committed stem cell

Author keywords (10)： progenitors ,  posterior gut endoderm cells ,  organoid ,  liver bud ,  transplant ,  human ,  pluripotent stem cells ,  iPSC ,  CDX2 ,  intestine

JST classification (2)： Cell physiology in general  (EF02010S) ,  Development(=generation)and differentiation  (EJ16020W)

Terms in the title (8)： ヒト ,  IPSC ,  後腸 ,  前駆細胞 ,  腸 ,  肝臓 ,  オルガノイド ,  拡張性