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J-GLOBAL ID：201802289441842491   Reference number：18A0381181

Branched-chain amino acids alleviate hepatic steatosis and liver injury in choline-deficient high-fat diet induced NASH mice

コリン不足の高脂肪食誘発NASHマウスにおける脂肪肝および肝損傷を軽減する分枝鎖アミノ酸【Powered by NICT】

Author (16)： Honda Takashi (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Ishigami Masatoshi (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Luo Fangqiong (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Lingyun Ma (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Ishizu Yoji (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Kuzuya Teiji (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Hayashi Kazuhiko (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Nakano Isao (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Ishikawa Tetsuya (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Feng Guo-Gang (Department of Pharmacology, Aichi Medical University School of Medicine, Nagakute, Japan) ,  Katano Yoshiaki (Department of Gastroenterology, Banbuntane Hotokukai Hospital, Fujita Health University School of Medicine, Nagoya, Japan) ,  Kohama Tomoya (Laboratory of Nutritional Biochemistry, Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan) ,  Kitaura Yasuyuki (Laboratory of Nutritional Biochemistry, Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan) ,  Shimomura Yoshiharu (Laboratory of Nutritional Biochemistry, Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan) ,  Goto Hidemi (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Hirooka Yoshiki (Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan)
Material： Metabolism  (Clinical and Experimental)
Volume： 69  Page： 177-187  Publication year： 2017 
JST Material Number： B0230B  ISSN： 0026-0495  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： For successful treatment for n...

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Thesaurus term： gene expression ,  lipid metabolism ,  triglyceride ,  hepatic dysfunction ,  alanine aminotransferase ,  *fatty liver ,  *high fat diet ,  *branched-chain amino acid ,  inflammation ,  therapy ,  serum ,  sterol ,  alicyclic alcohol ,  aliphatic amine ,  aliphatic alcohol ,  quaternary ammonium ,  aminoalcohol
Semi thesaurus term： 脂肪蓄積 ,  *非アルコール性脂肪性肝炎 , 【Automatic Indexing@JST】

Author keywords (5)： NASH ,  BCAA ,  Steatosis ,  Fatty acid synthase ,  Cholesterol

JST classification (1)： Digestive system diseases  (GH03000W)

Substance index (2)： Cholesterol ,  Choline

Terms in the title (8)： コリン ,  高脂肪食 ,  誘発 ,  NASH ,  マウス ,  脂肪肝 ,  肝損傷 ,  分枝鎖アミノ酸