Art

J-GLOBAL ID：201802289607858277   Reference number：18A0923193

Pharmacokinetics of single-dose sildenafil administered orally in clinically healthy dogs: Effect of feeding and dose proportionality

臨床的に健康なイヌにおいて経口投与した単回投与シルデナフィルの薬物動態:給餌と用量比例性の影響【JST・京大機械翻訳】

Author (6)： Akabane R. (Laboratory of Veterinary Internal Medicine II, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino-shi, Japan) ,  Sato T. (Laboratory of Biomolecular Chemistry, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino-shi, Japan) ,  Sakatani A. (Laboratory of Veterinary Internal Medicine II, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino-shi, Japan) ,  Miyagawa Y. (Laboratory of Veterinary Internal Medicine II, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino-shi, Japan) ,  Tazaki H. (Laboratory of Biomolecular Chemistry, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino-shi, Japan) ,  Takemura N. (Laboratory of Veterinary Internal Medicine II, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino-shi, Japan)
Material： Journal of Veterinary Pharmacology and Therapeutics  (J Vet Pharmacol Ther)
Volume： 41  Issue： 3  Page： 457-462  Publication year： 2018 
JST Material Number： W1722A  ISSN： 0140-7783  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Basic information related to t...

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Thesaurus term： *administration (biology) ,  Fasting ,  *single administration ,  *pharmacokinetics ,  crossover trial ,  plasma concentration ,  high performance liquid chromatography ,  Half-Life ,  *oral administration ,  area under the blood concentration time curve ,  pharmacokinetic parameter
Semi thesaurus term： 健康 , 【Automatic Indexing@JST】

Author keywords (5)： dog ,  dose proportionality ,  feeding ,  pharmacokinetics ,  sildenafil

JST classification (2)： Basic biopharmacy  (GY01021U) ,  Chromatography and electrophoretic analysis of organic compounds  (CC04034H)

Substance index (1)： Sildenafil

Terms in the title (9)： 臨床 ,  イヌ ,  経口投与 ,  単回投与 ,  シルデナフィル ,  薬物動態 ,  給餌 ,  用量 ,  比例