Art

J-GLOBAL ID：201802289774213960   Reference number：18A1297765

Translation of CRISPR Genome Surgery to the Bedside for Retinal Diseases

網膜疾患に対するCRISPRゲノム手術のベッドサイドへの翻訳【JST・京大機械翻訳】

Author (16)： Xu Christine L. (Jonas Children’s Vision Care, Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University) ,  Xu Christine L. (Department of Ophthalmology, Columbia University) ,  Cho Galaxy Y. (Jonas Children’s Vision Care, Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University) ,  Cho Galaxy Y. (Department of Ophthalmology, Columbia University) ,  Cho Galaxy Y. (Frank. H. Netter MD School of Medicine, Quinnipiac University) ,  Sengillo Jesse D. (Jonas Children’s Vision Care, Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University) ,  Sengillo Jesse D. (Department of Ophthalmology, Columbia University) ,  Sengillo Jesse D. (State University of New York Downstate Medical Center) ,  Park Karen S. (Jonas Children’s Vision Care, Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University) ,  Park Karen S. (Department of Ophthalmology, Columbia University) ,  Mahajan Vinit B. (Omics Lab, Department of Ophthalmology, Byers Eye Institute, Stanford University) ,  Mahajan Vinit B. (Palo Alto Veterans Administration) ,  Tsang Stephen H. (Jonas Children’s Vision Care, Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University) ,  Tsang Stephen H. (Department of Ophthalmology, Columbia University) ,  Tsang Stephen H. (Department of Pathology & Cell Biology, Columbia University) ,  Tsang Stephen H. (Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University)
Material： Frontiers in Cell and Developmental Biology (Web)
Volume： 6  Page： 46  Publication year： 2018 
JST Material Number： U7062A  ISSN： 2296-634X  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： In recent years, there has bee...

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Thesaurus term： *retina ,  clustering ,  *genome ,  clinical trial ,  ophthalmology ,  surgical technique ,  *retinal disease ,  operative surgery
Semi thesaurus term： Cas9 ,  治療用途 ,  動物モデル ,  網膜ジストロフィー ,  遺伝性網膜ジストロフィー ,  *CRISPR配列 , 【Automatic Indexing@JST】

Author keywords (5)： genome surgery ,  CRISPR-Cas9 ,  retinal dystrophies ,  clinical trials ,  off-target effect

JST classification (1)： Gene manipulation  (EC02050B)

Terms in the title (6)： 網膜疾患 ,  CRISPR ,  ゲノム ,  手術 ,  ベッド ,  翻訳