Art

J-GLOBAL ID：201802289804597551   Reference number：18A0091796

Nafamostat mesilate, a serine protease inhibitor, suppresses interferon-gamma-induced up-regulation of programmed cell death ligand 1 in human cancer cells

セリンプロテアーゼ阻害剤,メシル酸ナファモスタットはヒト癌細胞におけるプログラム細胞死リガンド1のインターフェロンガンマ誘導アップレギュレーションを抑制する【Powered by NICT】

Author (7)： Homma Sadamu (Division of Oncology, Research Centre for Medical Sciences, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi Minato-ku, Tokyo 105-8461, Japan) ,  Hayashi Kazumi (Division of Oncology, Research Centre for Medical Sciences, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi Minato-ku, Tokyo 105-8461, Japan) ,  Hayashi Kazumi (Division of Clinical Oncology/Haematology, Department of Internal Medicine, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi Minato-ku, Tokyo 105-8461, Japan) ,  Yoshida Kosaku (Division of Oncology, Research Centre for Medical Sciences, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi Minato-ku, Tokyo 105-8461, Japan) ,  Sagawa Yukiko (Division of Oncology, Research Centre for Medical Sciences, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi Minato-ku, Tokyo 105-8461, Japan) ,  Kamata Yuko (Division of Oncology, Research Centre for Medical Sciences, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi Minato-ku, Tokyo 105-8461, Japan) ,  Ito Masaki (Division of Oncology, Research Centre for Medical Sciences, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi Minato-ku, Tokyo 105-8461, Japan)
Material： International Immunopharmacology  (Int Immunopharmacol)
Volume： 54  Page： 39-45  Publication year： 2018 
JST Material Number： T0026B  ISSN： 1567-5769  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Programmed cell death ligand-1...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A0091796&from=J-GLOBAL&jstjournalNo=T0026B") }}

Thesaurus term： NF-kappaB ,  interaction ,  antitumor action ,  *tumor cell ,  monoclonal antibody ,  mRNA ,  *Up-Regulation ,  *Cell Death ,  phosphorylation ,  tumor immunity ,  *interferon gamma ,  *human ,  Antigens, CD274 ,  *Ligands ,  *programmed cell death

Author keywords (6)： Nafamostat mesilate ,  Programmed cell death ligand-1 ,  Interferon-gamma ,  Programmed cell death-1 ,  Human leukocyte antigen class I ,  Lung cancer

JST classification (4)： Cytokines  (EB08090G) ,  Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Biological function  (EB02020R) ,  Cell physiology in general  (EF02010S)

Terms in the title (9)： セリンプロテアーゼ阻害剤 ,  メシル酸ナファモスタット ,  ヒト ,  癌細胞 ,  プログラム細胞死 ,  リガンド ,  インターフェロンガンマ ,  誘導 ,  アップレギュレーション