Art
J-GLOBAL ID：201802289876216416   Reference number：18A1995019

Pharmacokinetics and Pharmacodynamics of Luseogliflozin, a Selective SGLT2 Inhibitor, in Japanese Patients With Type 2 Diabetes With Mild to Severe Renal Impairment

軽度から重度の腎障害を伴う2型糖尿病の日本人患者における選択的SGLT2阻害剤,ルセオグリフロジンの薬物動態と薬力学【JST・京大機械翻訳】
Author (8)：
Samukawa Yoshishige

About Samukawa Yoshishige

(Taisho Pharmaceutical Co., Ltd., Tokyo, Japan)

About Taisho Pharmaceutical Co., Ltd., Tokyo, Japan

, 
Haneda Masakazu

About Haneda Masakazu

(Division of Metabolism and Biosystemic Science, Department of Medicine, Asahikawa Medical University, Hokkaido, Japan)

About Division of Metabolism and Biosystemic Science, Department of Medicine, Asahikawa Medical University, Hokkaido, Japan

, 
Seino Yutaka

About Seino Yutaka

(Kansai Electric Power Hospital, Osaka, Japan)

About Kansai Electric Power Hospital, Osaka, Japan

, 
Sasaki Takashi

About Sasaki Takashi

(Institute of Clinical Medicine and Research, The Jikei University School of Medicine, Chiba, Japan)

About Institute of Clinical Medicine and Research, The Jikei University School of Medicine, Chiba, Japan

, 
Fukatsu Atsushi

About Fukatsu Atsushi

(Yachiyo Hospital, Aichi, Japan)

About Yachiyo Hospital, Aichi, Japan

, 
Kubo Yusuke

About Kubo Yusuke

(Taisho Pharmaceutical Co., Ltd., Tokyo, Japan)

About Taisho Pharmaceutical Co., Ltd., Tokyo, Japan

, 
Sato Yuri

About Sato Yuri

(Taisho Pharmaceutical Co., Ltd., Tokyo, Japan)

About Taisho Pharmaceutical Co., Ltd., Tokyo, Japan

, 
Sakai Soichi

About Sakai Soichi

(Taisho Pharmaceutical Co., Ltd., Tokyo, Japan)

About Taisho Pharmaceutical Co., Ltd., Tokyo, Japan


Material：
Clinical Pharmacology in Drug Development

About Clinical Pharmacology in Drug Development


Volume： 7  Issue： 8  Page： 820-828  Publication year： 2018 
JST Material Number： W2780A  ISSN： 2160-7648  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
excretion

About excretion

, 
*type 2 diabetes mellitus

About type 2 diabetes mellitus

, 
*patient

About patient

, 
*pharmacodynamics

About pharmacodynamics

, 
*kidney disease

About kidney disease

, 
safety

About safety

, 
*pharmacokinetics

About pharmacokinetics

, 
administration(biology)

About administration(biology)

, 
plasma(blood)

About plasma(blood)

, 
plasma concentration

About plasma concentration

, 
hexose

About hexose

, 
aldose

About aldose


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
腎機能

About 腎機能

, 
腎機能障害

About 腎機能障害

, 
*日本人

About 日本人

, 【Automatic Indexing@JST】
Author keywords (5)：
luseogliflozin

About luseogliflozin

, 
T2DM patients

About T2DM patients

, 
renal impairment

About renal impairment

, 
pharmacokinetics

About pharmacokinetics

, 
pharmacodynamics

About pharmacodynamics

JST classification (5)：
JST classification
Category name(code) classified by JST.
Clinical biopharmacy 
(GY01022L)

About Clinical biopharmacy

,  Physicochemical characteristics of drugs 
(GV01060M)

About Physicochemical characteristics of drugs

,  Clinical application of vasoactive drugs and hypotensive drugs 
(GW07050U)

About Clinical application of vasoactive drugs and hypotensive drugs

,  Clinical medicine on urogenital system in general 
(GM01030E)

About Clinical medicine on urogenital system in general

,  Drug therapy(=pharmacotherapy)for cardiovascular system diseases 
(GJ05020M)

About Drug therapy(=pharmacotherapy)for cardiovascular system diseases

Substance index (2)：
Substance index
Chemical Substance indexed to the Article.
Glucose

About Glucose

, 
Luseogliflozin

About Luseogliflozin

Terms in the title (9)：
Terms in the title
Keywords automatically extracted from the title.
軽度

About 軽度

, 
腎障害

About 腎障害

, 
2型糖尿病

About 2型糖尿病

, 
日本人

About 日本人

, 
患者

About 患者

, 
SGLT2阻害剤

About SGLT2阻害剤

, 
ルセオグリフロジン

About ルセオグリフロジン

, 
薬物動態

About 薬物動態

, 
薬力学

About 薬力学


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