Art
J-GLOBAL ID：201802290428104846
Reference number：18A0120425
Long-term treatment with EGFR inhibitor erlotinib attenuates renal inflammatory cytokines but not nephropathy in Alport syndrome mouse model
EGFR阻害薬エルロチニブを用いた長期治療はアルポート症候群マウスモデルにおいて腎炎症性サイトカインを減少させるが腎症は緩和しない
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Material：
Volume：
21
Issue：
6
Page：
952-960
Publication year：
Dec. 2017
JST Material Number：
L3173A
ISSN：
1342-1751
Document type：
Article
Article type：
原著論文
Country of issue：
Germany, Federal Republic of (DEU)
Language：
ENGLISH (EN)
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JST classification (1)：
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Basic medicine on urogenital system
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Reference (32)：
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Hudson BG, Tryggvason K. Alport“s syndrome, Goodpasture”s syndrome, and type IV collagen. N Engl J Med. 2003;348:2543-56.
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Suleiman H, Zhang L, Roth R, Heuser JE, Miner JH. Nanoscale protein architecture of the kidney glomerular basement membrane. eLife. 2013;2:e01149.
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Zallocchi M, Johnson BM, Meehan DT. α1β1 integrin/Rac1-dependent mesangial invasion of glomerular capillaries in Alport syndrome. Am J Pathol. 2013;183:1269-80.
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Randles MJ, Collinson S, Starborg T, Mironov A, Krendel M, Königshausen E, et al. Three-dimensional electron microscopy reveals the evolution of glomerular barrier injury. Sci Rep Nat Publ Group; 2016;6:35068.
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Gross O, Beirowski B, Koepke ML, Kuck J. Preemptive ramipril therapy delays renal failure and reduces renal fibrosis in COL4A3-knockout mice with Alport syndrome1. Kidney Int. 2003;63:438-46.
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