Art

J-GLOBAL ID：201802290865713003   Reference number：18A1644353

Protein kinase A (PKA) inhibition reduces human aortic smooth muscle cell calcification stimulated by inflammatory response and inorganic phosphate

蛋白質キナーゼA(PKA)阻害は炎症反応と無機リン酸により刺激されるヒト大動脈平滑筋細胞石灰化を減少させる【JST・京大機械翻訳】

Author (10)： Toita Riki (Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan) ,  Toita Riki (AIST-Osaka University Advanced Photonics and Biosensing Open Innovation Laboratory, AIST, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Otani Kentaro (Department of Regenerative Medicine and Tissue Engineering, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan) ,  Kawano Takahito (Department of Advanced Medical Initiatives, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan) ,  Kawano Takahito (Faculty of Medical Sciences and Center for Advanced Medical Innovation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan) ,  Fujita Satoshi (Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan) ,  Fujita Satoshi (AIST-Osaka University Advanced Photonics and Biosensing Open Innovation Laboratory, AIST, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Murata Masaharu (Department of Advanced Medical Initiatives, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan) ,  Murata Masaharu (Faculty of Medical Sciences and Center for Advanced Medical Innovation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan) ,  Kang Jeong-Hun (Division of Biopharmaceutics and Pharmacokinetics, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan)
Material： Life Sciences  (Life Sciences including Pharmacology Letters)
Volume： 209  Page： 466-471  Publication year： 2018 
JST Material Number： B0699B  ISSN： 0024-3205  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Smooth muscle cells (SMCs) pla...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A1644353&from=J-GLOBAL&jstjournalNo=B0699B") }}

Thesaurus term： *phosphoric acid ,  *calcification ,  *smooth muscle cell ,  *human(primates) ,  serum ,  interferon gamma ,  siRNA ,  p38 MAP kinase ,  TNF ,  *protein kinase A ,  calcium ,  interleukin ,  *inflammation
Semi thesaurus term： 阻害剤 ,  Erk1/2 , 【Automatic Indexing@JST】

Author keywords (6)： Calcification ,  Cytokine ,  Inflammation ,  Macrophage ,  Phosphate ,  Smooth muscle cell

JST classification (3)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Cell physiology in general  (EF02010S) ,  Basic research of anti-inflammatory drugs  (GW15010T)

Terms in the title (9)： 蛋白質キナーゼA ,  PKA ,  阻害 ,  炎症反応 ,  無機リン酸 ,  刺激 ,  ヒト ,  大動脈平滑筋細胞 ,  石灰化