Art

J-GLOBAL ID：201802290893776410   Reference number：18A0843878

EGFR T790M and C797S Mutations as Mechanisms of Acquired Resistance to Dacomitinib

Dacomitinibに対する後天性抵抗性の機序としてのEGFR T790MおよびC797S変異【JST・京大機械翻訳】

Author (11)： Kobayashi Yoshihisa (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Fujino Toshio (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Nishino Masaya (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Koga Takamasa (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Chiba Masato (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Sesumi Yuichi (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Ohara Shuta (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Shimoji Masaki (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Tomizawa Kenji (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Takemoto Toshiki (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Mitsudomi Tetsuya (Department of Thoracic Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan)
Material： Journal of Thoracic Oncology
Volume： 13  Issue： 5  Page： 727-731  Publication year： 2018 
JST Material Number： W3145A  ISSN： 1556-0864  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Dacomitinib was superior to ge...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A0843878&from=J-GLOBAL&jstjournalNo=W3145A") }}

Thesaurus term： in vitro experiment ,  mutagenesis ,  lung tumor ,  *EGF receptor ,  clone ,  sensitivity ,  adenocarcinoma ,  mutation ,  patient ,  subset ,  *variation(biology) ,  enzyme inhibitor
Semi thesaurus term： EGFRチロシンキナーゼ阻害剤 ,  低用量 ,  阻害剤 , 【Automatic Indexing@JST】

Author keywords (5)： Adenocarcinoma ,  Dacomitinib ,  EGFR mutation ,  Lung cancer ,  Tyrosine kinase inhibitor

JST classification (2)： Tumors(=neoplasms)of respiratory system  (GI04000G) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Erlotinib

Terms in the title (3)： 抵抗性 ,  EGFR ,  変異