Art

J-GLOBAL ID：201802291659065522   Reference number：18A1562071

酸性環境における腫瘍の悪性化機構

Author (2)： KONDO AYANO (協和発酵キリン) ,  OSAWA TSUYOSHI (東大 先端科技セ)
Material： 生化学
Volume： 90  Issue： 4  Page： 502-506  Publication year： Aug. 25, 2018 
JST Material Number： G0184A  ISSN： 0037-1017  CODEN： SEIKAQ  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： tumor ,...
Semi thesaurus term： SREBP2 ,...

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JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (14)：

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• Semenza, G.L. (2003) Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer, 3, 721-732.
• Greer, E.L., Oskoui, P.R., Banko, M.R., Maniar, J.M., Gygi, M.P., Gygi, S.P., & Brunet, A. (2007) The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J. Biol. Chem., 282, 30107-30119.
• Gwinn, D.M., Shackelford, D.B., Egan, D.F., Mihaylova, M.M., Mery, A., Vasquez, D.S., Turk, B.E., & Shaw, R.J. (2008) AMPK phosphorylation of raptor mediates a metabolic checkpoint. Mol. Cell, 30, 214-226.
• Pugh, C.W. & Ratcliffe, P.J. (2003) Regulation of angiogenesis by hypoxia: Role of the HIF system. Nat. Med., 9, 677-684.

Terms in the title (3)： 酸性 ,  環境 ,  腫瘍