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J-GLOBAL ID:201802293862453636   Reference number:18A2052394

Comprehensive immunohistochemical analyses on expression levels of hedgehog signaling molecules in breast cancers

乳癌におけるヘッジホッグシグナル伝達分子の発現レベルの包括的免疫組織化学解析
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Volume: 25  Issue:Page: 759-767  Publication year: Nov. 2018 
JST Material Number: L3971A  ISSN: 1340-6868  Document type: Article
Article type: 原著論文  Country of issue: Germany, Federal Republic of (DEU)  Language: ENGLISH (EN)
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Chemistry,biochemistry and pathology of tumors(=neoplasms) 
Reference (21):
  • Hui M, Cazet A, Nair R, Watkins DN, O’Toole SA, Swarbrick A. The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy. Breast Cancer Res. 2013;15:203.
  • Gonnissen A, Isebaert S, Haustermans K. Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened. Oncotarget. 2015;6:13899-913.
  • Cui W, Wang LH, Wen YY, Song M, Li BL, Chen XL, et al. Expression and regulation mechanisms of Sonic Hedgehog in breast cancer. Cancer Sci. 2010;101:927-33.
  • Duan ZH, Wang HC, Zhao DM, Ji XX, Song M, Yang XJ, et al. Cooperatively transcriptional and epigenetic regulation of sonic hedgehog overexpression drives malignant potential of breast cancer. Cancer Sci. 2015;106:1084-91.
  • Benvenuto M, Masuelli L, De Smaele E, Fantini M, Mattera R, Cucchi D, et al. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors. Oncotarget. 2016;7:9250-70.
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