Research field (7)：
Mathematical informatics
, Human pathology
, Bio-, chemical, and soft-matter physics
, Biophysics
, Molecular biology
, Neuroanatomy and physiology
, Neuroscience - general
Research theme for competitive and other funds (2)：
2024 - 2027 CWAS Analysis to Profile Comprehensive Neurodegenerative Lesions Towards Integrated Omics
2020 - 2023 全脳ニューロンアトラスによる神経変性疾患モデルの一細胞解像度全脳病態解析
Papers (10)：
Rin Yanai, Tomoki T Mitani, Etsuo A Susaki, Takeharu Minamihisamatsu, Masafumi Shimojo, Yuri Saito, Hiroshi Mizuma, Nobuhiro Nitta, Daita Kaneda, Yoshio Hashizume, et al. A novel tauopathy model mimicking molecular and spatial aspects of human tau pathology. Brain Communications. 2024
Katsuhiko Matsumoto, Shoko Y. Harada, Shota Y. Yoshida, Ryohei Narumi, Tomoki T. Mitani, Saori Yada, Aya Sato, Eiichi Morii, Yoshihiro Shimizu, Hiroki R. Ueda. Genome-wide epitope identification with single-amino-acid resolution via high-throughput and unbiased peptide analysis. 2024
Tomoki T Mitani, Etsuo A Susaki, Katsuhiko Matsumoto, Hiroki R Ueda. Realization of cellomics to dive into the whole-body or whole-organ cell cloud. Nature methods. 2024
Tomoki T Mitani, Katsuhiko Matsumoto, Hiroki R Ueda. WHOLE-BRAIN CELLOME-WIDE ASSOCIATION STUDY (CWAS) UNVEILS NEURODEGENERATIVE TRAJECTORIES IN A 3D CELLULAR LANDSCAPE. IBRO Neuroscience Reports. 2023. 15. 1. S451-S451
Daisuke Tone, Koji L. Ode, Qianhui Zhang, Hiroshi Fujishima, Rikuhiro G. Yamada, Yoshiki Nagashima, Katsuhiko Matsumoto, Zhiqing Wen, Shota Y. Yoshida, Tomoki T. Mitani, et al. Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep. PLOS Biology. 2022. 20. 10. e3001813-e3001813
MICROSCOPE, VIEWING METHOD, CONTROL PROGRAM AND DEVICE
Books (3)：
Next-generation whole-organ all-cell imaging driven by MOVIE microscopy
2023
3D pathology by tissue-clearing technique
Precision Medicine 2023
Whole-organ cells profiling using tissue-clearing method "CUBIC"
Precision Medicine 2019
Lectures and oral presentations (21)：
Whole-brain Cellome-Wide Association Study (CWAS) Unveils Ultra-Early Neurodegeneration Phenomena in a 3D Spatial Cell Atlas
(2024)
Whole-brain Cellome-Wide Association Study (CWAS) Unveils Ultra-Early Neurodegeneration Phenomena in a 3D Spatial Cell Atlas
(Alzheimer’s Imaging Consortium (AIC) Preconference 2024)
Whole-Brain Cellome-Wide Association Study (CWAS) reveals Microscale Neurodegenerative Trajectories in a 3D Cellular Landscape
(National Institutes for Quantum Science and Technology (QST) 2024)
Whole-Brain Cellome-Wide Association Study (CWAS) reveals Microscale Neurodegenerative Trajectories in a 3D Cellular Landscape
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
Cellome-Wide Association Studies (CWAS) for Comprehensive 3D Analysis of Spatial Lesions and Microenvironments
(An invitation-only seminar hosted by Beth Israel Deaconess Medical Center/Harvard Medical School 2023)
