J-GLOBAL ID:201901001784877169   Update date: Feb. 01, 2024

Ibaraki Hisako

イバラキ ヒサコ | Ibaraki Hisako
Affiliation and department:
Job title: 助手
Research field  (1): Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds  (3):
  • 2021 - 2024 非侵襲的で自己投与可能なmRNAワクチンの実現に向けた皮膚浸透性ナノ粒子の開発
  • 2018 - 2021 Development of liposomes with excellent dermal delivery
  • 2019 - Development of a novel siRNA delivery system for cancer treatment using a tight ju nction opening peptide modified tumor penetrable liposome
Papers (19):
  • Shogo Nishida, Yuuki Takashima, Ryotaro Udagawa, Hisako Ibaraki, Yasuo Seta, Hiroshi Ishihara. A Multifunctional Hybrid Nanocarrier for Non-Invasive siRNA Delivery to the Retina. Pharmaceutics. 2023. 15. 2
  • Hisako Ibaraki, Naruhiro Hatakeyama, Akihiro Takeda, Naoki Arima, Takanori Kanazawa. Multifunctional peptide carrier-modified polymer micelle accelerates oral siRNA-delivery to the colon and improves gene silencing-mediated therapeutic effects in ulcerative colitis. Journal of Drug Delivery Science and Technology. 2022. 73
  • Takumi Kurano, Takanori Kanazawa, Aoi Ooba, Yudai Masuyama, Nao Maruhana, Mayu Yamada, Shingo Iioka, Hisako Ibaraki, Yasuhiro Kosuge, Hiromu Kondo, et al. Nose-to-brain/spinal cord delivery kinetics of liposomes with different surface properties. Journal of controlled release : official journal of the Controlled Release Society. 2022. 344. 225-234
  • Hisako Ibaraki, Takanori Kanazawa. In Vivo Topical and Systemic Distribution Kinetics of Liposomes with Various Properties for Application to Drug Delivery Systems. Sensors and Materials. 2022. 34. 3. 987-1005
  • Hisako Ibaraki, Naruhiro Hatakeyama, Naoki Arima, Akihiro Takeda, Yasuo Seta, Takanori Kanazawa. Systemic delivery of siRNA to the colon using peptide modified PEG-PCL polymer micelles for the treatment of ulcerative colitis. European Journal of Pharmaceutics and Biopharmaceutics. 2022. 170. 170-178
MISC (83):
Patents (1):
  • 核酸送達用組成物及び核酸含有組成物
Lectures and oral presentations  (48):
  • 脳虚血再灌流障害治療における抗TNF-α siRNAのNose-to-Brainデリバリーのための細胞透過性ペプチド修飾高分子ミセルの有用性
    (第34回日本DDS学会学術集会 2019)
  • 蛍光イメージングを用いた塩基性ペプチド併用による水溶性高分子のNose-to-Brainデリバリー動態の観察
    (日本薬学会 第139年会 2019)
  • 皮内デリバリーに及ぼすリポソームの表面電荷の影響
    (日本薬学会 第139年会 2019)
  • Evaluation of Pseudomonas aeruginosa biofilm retention and membrane damage by liposomes with different surface properties
    (The 3rd Workshop for Japan-Korea Young Scientists on Pharmaceutics 2019)
  • Evaluation of liposomal surface charge for effective siRNA dermal delivery
    (The 3rd Workshop for Japan-Korea Young Scientists on Pharmaceutics 2019)
Professional career (1):
  • 博士(薬学) (東京薬科大学)
Work history (1):
  • 2014/04 - 現在 Shool of Pharmacy, Tokyo University of Pharmacy and Life Sciences Research Associate
Awards (4):
  • 2019/09 - 第25回創剤フォーラム若手研究会 Best Poster Presentation Award
  • 2019/09 - 第28回DDSカンファランス Postdoctoral Presentation Award 2019
  • 2017/09 - 9th JARI_4rdJSEV 優秀口頭発表賞
  • 2014/11 - 第20回創剤フォーラム若手研究会 最優秀ポスター発表賞(プラチナ賞)
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