Ibaraki Hisako

イバラキヒサコ | Ibaraki Hisako

Affiliation and department：
Job title：助手

Research field (1)： Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (3)：

2021 - 2024 非侵襲的で自己投与可能なmRNAワクチンの実現に向けた皮膚浸透性ナノ粒子の開発
2018 - 2021 Development of liposomes with excellent dermal delivery
2019 - Development of a novel siRNA delivery system for cancer treatment using a tight ju nction opening peptide modified tumor penetrable liposome

Papers (19)：

Shogo Nishida, Yuuki Takashima, Ryotaro Udagawa, Hisako Ibaraki, Yasuo Seta, Hiroshi Ishihara. A Multifunctional Hybrid Nanocarrier for Non-Invasive siRNA Delivery to the Retina. Pharmaceutics. 2023. 15. 2
Hisako Ibaraki, Naruhiro Hatakeyama, Akihiro Takeda, Naoki Arima, Takanori Kanazawa. Multifunctional peptide carrier-modified polymer micelle accelerates oral siRNA-delivery to the colon and improves gene silencing-mediated therapeutic effects in ulcerative colitis. Journal of Drug Delivery Science and Technology. 2022. 73
Takumi Kurano, Takanori Kanazawa, Aoi Ooba, Yudai Masuyama, Nao Maruhana, Mayu Yamada, Shingo Iioka, Hisako Ibaraki, Yasuhiro Kosuge, Hiromu Kondo, et al. Nose-to-brain/spinal cord delivery kinetics of liposomes with different surface properties. Journal of controlled release : official journal of the Controlled Release Society. 2022. 344. 225-234
Hisako Ibaraki, Takanori Kanazawa. In Vivo Topical and Systemic Distribution Kinetics of Liposomes with Various Properties for Application to Drug Delivery Systems. Sensors and Materials. 2022. 34. 3. 987-1005
Hisako Ibaraki, Naruhiro Hatakeyama, Naoki Arima, Akihiro Takeda, Yasuo Seta, Takanori Kanazawa. Systemic delivery of siRNA to the colon using peptide modified PEG-PCL polymer micelles for the treatment of ulcerative colitis. European Journal of Pharmaceutics and Biopharmaceutics. 2022. 170. 170-178

ｍore...

MISC (83)：

尾熊貴之, 尾熊貴之, 金沢貴憲, 茨木ひさ子, 高島由季, 近藤啓. Intra-tumor distribution and anti-tumor effects of permeable siRNA-encapsulated liposome. 日本核酸医薬学会年会講演要旨集(CD-ROM). 2022. 7th
金沢貴憲, 茨木ひさ子, 高島由季, 近藤啓. 組織浸透性核酸内封リポソームの開発と静脈投与後の腫瘍内浸透性および抗腫瘍効果の検証. 生体膜と薬物の相互作用シンポジウム講演要旨集. 2022. 43rd
茨木ひさ子, 金沢貴憲. Design of Intratissue-Penetrating siRNA Delivery System Targeted for Intercellular Route. 月刊ファインケミカル. 2021. 50. 6
Hisako Ibaraki. siRNA組織内浸透型DDSの構築 (若手研究者紹介). 2020. 80. 3. 132-136
滝口すみれ, 茨木ひさ子, 金沢貴憲, 金沢貴憲, 高島由季, 瀬田康生. BxPC-3皮下移植マウスにおける腫瘍内浸透型siRNA内封リポソーム静脈内投与後の抗腫瘍効果. 日本DDS学会学術集会プログラム予稿集. 2020. 36th

ｍore...

Patents (1)：

Lectures and oral presentations (48)：

脳虚血再灌流障害治療における抗TNF-α siRNAのNose-to-Brainデリバリーのための細胞透過性ペプチド修飾高分子ミセルの有用性
(第34回日本DDS学会学術集会 2019)
蛍光イメージングを用いた塩基性ペプチド併用による水溶性高分子のNose-to-Brainデリバリー動態の観察
(日本薬学会第139年会 2019)
皮内デリバリーに及ぼすリポソームの表面電荷の影響
(日本薬学会第139年会 2019)
Evaluation of Pseudomonas aeruginosa biofilm retention and membrane damage by liposomes with different surface properties
(The 3rd Workshop for Japan-Korea Young Scientists on Pharmaceutics 2019)
Evaluation of liposomal surface charge for effective siRNA dermal delivery
(The 3rd Workshop for Japan-Korea Young Scientists on Pharmaceutics 2019)

ｍore...

Professional career (1)：

Work history (1)：

2014/04 - 現在 Shool of Pharmacy, Tokyo University of Pharmacy and Life Sciences Research Associate

Awards (4)：

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page