Research keywords (4)：
epigenetics
, autoimmune
, renin-angiotesin-aldosterone system
, Endocrinology
Research theme for competitive and other funds (4)：
2021 - 2024 高血圧診療の革新を目指す原発性アルドステロン症の自己抗体研究
2019 - 2022 転写因子・作用蛋白の同定による表皮の分化・脱核機構の解明
2017 - 2020 Establishment of autoimmune primary aldosteronism and development of autoantibody assay
2009 - 2011 Molecular genetic analyses of the CYP11B2 gene in cardiovascular tissues
Papers (111)：
Ren Mizoguchi, Shigehiro Karashima, Yuna Miyajima, Kohei Ogura, Mitsuhiro Kometani, Daisuke Aono, Seigo Konishi, Masashi Demura, Hiromasa Tsujiguchi, Akinori Hara, et al. Impact of gut microbiome on the renin-aldosterone system: Shika-machi Super Preventive Health Examination results. Hypertension research : official journal of the Japanese Society of Hypertension. 2023
Yoshimichi Takeda, Masashi Demura, Mitsuhiro Kometani, Shigehiro Karashima, Takashi Yoneda, Yoshiyu Takeda. Molecular and Epigenetic Control of Aldosterone Synthase, CYP11B2 and 11-Hydroxylase, CYP11B1. International journal of molecular sciences. 2023. 24. 6
Masaki Kawakami, Shigehiro Karashima, Kento Morita, Hayato Tada, Hirofumi Okada, Daisuke Aono, Mitsuhiro Kometani, Akihiro Nomura, Masashi Demura, Kenji Furukawa, et al. Explainable Machine Learning for Atrial Fibrillation in the General Population Using a Generalized Additive Model - A Cross-Sectional Study. Circulation reports. 2022. 4. 2. 73-82
