Takado Yuhei

Takado Yuhei | Takado Yuhei

Affiliation and department：
Job title： Principal Researcher
Homepage URL (1)： https://brainenergy.xsrv.jp/

Research field (2)： Neuroscience - general , Neurology

Research keywords (12)： PET , Taurine , Alzheimer's Disease , Astrocyte , Brain energy metabolism , Translational Research , NanoSIMS , Brain metabolism , Hyperpolarized MRI , Neuroimaging , MRS , Neurodegenerative diseases

Research theme for competitive and other funds (7)：

2023 - 2025 Hyperpolarization by UV-induced radicals: developing and characterizing their application in vivo to investigate Alzheimer's disease
2022 - 2025 疼痛の中枢性感作における生体内情報の処理過程に対する動的因果モデルの検証
2022 - 2025 Identification of astrocyte dysfunction molecules involved in the pathogenesis of dementia and elucidation of their mechanisms
2019 - 2023 興奮抑制バランス操作による脳の可塑性メカニズムの理解
2019 - 2022 E/I balance disruption in tau-related dementia

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Papers (84)：

Hironobu Endo, Maiko Ono, Yuhei Takado, Kiwamu Matsuoka, Manami Takahashi, Kenji Tagai, Yuko Kataoka, Kosei Hirata, Keisuke Takahata, Chie Seki, et al. Imaging α-synuclein pathologies in animal models and patients with Parkinson's and related diseases. Neuron. 2024
Kosei Hirata, Kiwamu Matsuoka, Kenji Tagai, Hironobu Endo, Harutsugu Tatebe, Maiko Ono, Naomi Kokubo, Yuko Kataoka, Asaka Oyama, Hitoshi Shinotoh, et al. In Vivo Assessment of Astrocyte Reactivity in Patients with Progressive Supranuclear Palsy. Annals of neurology. 2024
Takahiro Hirao, Mitsuhiro Miyamae, Daisuke Matsuyoshi, Ryuto Inoue, Yuhei Takado, Takayuki Obata, Makoto Higuchi, Naotsugu Tsuchiya, Makiko Yamada. A neuroimaging dataset during sequential color qualia similarity judgments with and without reports. 2024
Manabu Kubota, Hironobu Endo, Keisuke Takahata, Kenji Tagai, Hisaomi Suzuki, Mitsumoto Onaya, Yasunori Sano, Yasuharu Yamamoto, Shin Kurose, Kiwamu Matsuoka, et al. In vivo PET classification of tau pathologies in patients with frontotemporal dementia. Brain Communications. 2024
Kiwamu Matsuoka, Kosei Hirata, Naomi Kokubo, Takamasa Maeda, Kenji Tagai, Hironobu Endo, Keisuke Takahata, Hitoshi Shinotoh, Maiko Ono, Chie Seki, et al. Investigating neural dysfunction with abnormal protein deposition in Alzheimer's disease through magnetic resonance spectroscopic imaging, plasma biomarkers, and positron emission tomography. NeuroImage. Clinical. 2023. 41. 103560-103560

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MISC (53)：

松岡究, 松岡究, 平田浩聖, 小久保奈緒美, 前田貴雅, 互健二, 遠藤浩信, 高畑圭輔, 篠遠仁, 篠遠仁, et al. Magnetic resonance spectroscopic imaging enables spatial mapping of decreased cerebral glutamate levels associated with tau depositions in Alzheimer’s disease. 日本生物学的精神医学会(Web). 2023. 45th
下條雅文, 南久松丈晴, 高橋真奈美, 田桑弘之, 松下有美, 矢内凛, 湊原圭一郎, 小野麻衣子, 高堂裕平, 張明栄, et al. rTg4510認知症モデル動物脳における炎症性アストロサイト病態の画像解析. 日本神経化学会大会抄録集(Web). 2022. 65th
小野麻衣子, 高橋真奈美, 下沢明希, 藤永雅之, 森若菜, 永井裕司, 三村喬生, 熊田勝志, 下條雅文, 高堂裕平, et al. α-synuclein病変の蓄積・伝播を生体脳で可視化する分子プローブの開発. Dementia Japan. 2021. 35. 4
佐野康徳, 高畑圭輔, 久保田学, 山本保天, 島田斉, 高堂裕平, 互健二, 関千江, 黒瀬心, 鈴木寿臣, et al. 双極性障害では線条体におけるホスホジエステラーゼ10Aの密度が低下する. 日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集. 2019. 29回・49回. 253-253
互健二, 島田斉, 高畑圭輔, 久保田学, 佐野康徳, 山本保天, 篠遠仁, 仲野義和, 高堂裕平, 北村聡一郎, et al. レビー小体病におけるアルツハイマー病理は認知機能障害、萎縮、糖代謝障害に影響する. Dementia Japan. 2019. 33. 4. 527-527

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Patents (1)：

四足動物保定装置

Education (1)：

1995 - 2001 Niigata University Faculty of Medicine

Professional career (1)：

医学博士 (新潟大学)

Work history (10)：

2022/07 - 現在 National Institutes for Quantum and Radiological Science and Technology Institute for Quantum Life Science, Quantum Life and Medical Science Directorate Principal Researcher
2020/10 - 現在 National Institutes for Quantum and Radiological Science and Technology Department of Functional Brain Imaging Research, Brain Disorder Translational Research Group Principle Researcher
2015/10 - 現在放射線医学総合研究所(現・量子科学技術研究開発機構) 脳機能イメージング研究部研究員
2011 - 2015 EPFL
2010 - 2011 スイス連邦工科大学ローザンヌ校スイス政府奨学金留学生/博士研究員

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Association Membership(s) (9)：

JAPANESE SOCIETY FOR MAGNETIC RESONANCE IN MEDICINE , JAPANESE SOCIETY OF NUCLEAR MEDICINE , 国際タウリン研究会 , 臨床MR脳機能研究会 , THE JAPAN NEUROSCIENCE SOCIETY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , JAPAN SOCIETY FOR DEMENTIA RESEARCH , JAPANESE SOCIETY OF NEUROLOGY , ISMRM

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