Rchr
J-GLOBAL ID:201901003470001679   Update date: Jun. 24, 2025

Takahata Keisuke

タカハタ ケイスケ | Takahata Keisuke
Affiliation and department:
Job title: Chief Researcher
Other affiliations (2):
  • Keio University School of Medicine  Department of Neuropsychiatry 
  • Ichikawa Medical Clinic
Research field  (2): Psychiatry ,  Neuroscience - general
Research keywords  (15): CTE ,  Long COVID ,  tauopathy ,  organophosphate poisoning ,  cognitive impairment ,  late-life psychosis ,  Positron Emission Tomography (PET) ,  Neuropsychology ,  遅発性脳障害 ,  器質性精神障害 ,  Tau PET imaging ,  PET ,  Chronic Traumatic Encephalopathy ,  Punch-drunk syndrome, Dementia Pugilistica ,  Traumatic brain injury
Research theme for competitive and other funds  (15):
  • 2024 - 2028 中枢神経損傷による続発性タウオパチーの病態解明
  • 2022 - 2027 タウ・アミロイドPETおよび7テスラMRI/MRSによる中高年期精神疾患の層別化
  • 2024 - 2025 7TMRI・アミロイド・タウPETを用いた外傷性脳損傷後遺症・脳萎縮機序の解明
  • 2022 - 2025 スポーツ頭部外傷後遅発性脳障害に対するMRI・タウPETによる画像診断法の確立
  • 2021 - 2025 Investigation about underpinning neural mechanisms of sequelae and brain atrophy after brain injury
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Papers (116):
  • Kosei Nakamura, Kenji Tagai, Hitoshi Shinotoh, Shigeki Hirano, Soichiro Kitamura, Hironobu Endo, Keisuke Takahata, Yuhei Takado, Ming-Rong Zhang, Kazunori Kawamura, et al. Concurrent Alzheimer's disease pathologies in Lewy body diseases affect cognition and glucose metabolism in the posterior cingulate gyrus: A multimodal PET study. Journal of Alzheimer’s Disease. 2025
  • Miho Suganami, Keisuke Takahata, Yu Mimura, Masahiro Yamamoto, Hiroyuki Uchida, Taro Muramatsu, Masaru Mimura. Impact of brain damage on moral judgment. Psychiatry and Clinical Neurosciences Reports. 2025
  • Ryoji Goto, Kiwamu Matsuoka, Yasuyuki Kimura, Yuko Kataoka, Masaki Oya, Kosei Hirata, Kenji Tagai, Keisuke Takahata, Chie Seki, Kazunori Kawamura, et al. Human biodistribution and radiation dosimetry of two novel α-synuclein PET tracers, 18F-SPAL-T-06 and 18F-C05-05. Scientific reports. 2025. 15. 1. 8640-8640
  • Yasuharu Yamamoto, Keisuke Takahata, Morinobu Seki, Shohei Okusa, Harutsugu Tatebe, Ryo Ueda, Hironobu Endo, Kenji Tagai, Sho Moriguchi, Shin Kurose, et al. SLC9A6 -Linked Parkinson Syndrome in Female Heterozygotes Is Associated With PET-Detectable Tau Pathology. Neurology Genetics. 2025
  • Yuki Momota, Shogyoku Bun, Jinichi Hirano, Kei Kamiya, Ryo Ueda, Yu Iwabuchi, Keisuke Takahata, Yasuharu Yamamoto, Toshiki Tezuka, Masahito Kubota, et al. Amyloid-β prediction machine learning model using source-based morphometry across neurocognitive disorders. Scientific Reports. 2024. 14. 1. 7633-7633
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MISC (143):
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Books (10):
  • やさしい高次脳機能障害用語事典
    ぱーそん書房 2018 ISBN:9784907095482
  • 精神科身体合併症マニュアル
    医学書院 2018 ISBN:9784260035453
  • 今日の精神疾患治療指針
    医学書院 2016 ISBN:9784260024846
  • 認知リハビリテーション実践ガイド
    医学書院 2015 ISBN:9784260021456
  • Dementia
    2012 ISBN:4521734391
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Lectures and oral presentations  (27):
  • 神経変性疾患の前駆状態としての精神疾患 老年期精神障害と外傷性精神障害
    (神経心理懇話会 2024 2024)
  • 慢性外傷性脳症(CTE)のタウPET所見
    (第 43 回日本認知症学会学術集会 2024)
  • 新規TSPO-PETトレーサー18F-FEDACの脳内動態
    (第 64 回日本核医学会学術総会 2024)
  • 遅発性気分障害の神経病理学的病態:PETと剖検脳による検討
    (第43回躁うつ病の薬理・生化学的研究懇話会 2024)
  • 精神・神経臨床における脳核医学画像:臨床の基本から最新の進歩まで 精神神経疾患におけるPETを用いた病態可視化技術の開発と展望
    (第120回 日本精神神経学会学術総会 2024)
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Education (2):
  • 2008 - 2012 Keio University PhD course
  • 1997 - 2003 Keio University School of Medicine
Professional career (2):
  • PhD (Keio University Schools of Medicine)
  • MD (Keio University Schools of Medicine)
Work history (6):
  • 2024/04 - 現在 National Institutes for Quantum Science and Technology (QST) Advances Neuroimaging Center, Sector for NeuroPsychiatric Disease Research Sector Leader
  • 2023/04 - 現在 Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology (QST) Department of Functional Brain Imaging
  • 2015/04 - 現在 National Institute of Radiological Sciences (NIRS) National Institutes for Quantum and Radiological Science and Technology (QST) Chiba, Japan Department of Functional Brain Imaging Research Researcher
  • 2012/04 - 2015/03 National Institute of Radiological Sciences (NIRS) National Institutes for Quantum and Radiological Science and Technology (QST) Chiba, Japan Department of Functional Brain Imaging Research PosDoc Reearcher
  • 2005/04 - 2008/03 Tachikawa Hospital Department of Psychiatry
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Committee career (3):
  • 2022/04 - 現在 Psychiatry and Clinical Neurosciences Reports Psychiatry and Clinical Neurosciences Reports Journal Editor
  • 2021/08 - 現在 Neuropsychology Association of Japan councilor
  • 2021/11 - Japan Society of Higher Brain Dysfunction a representative
Awards (4):
  • 2023/11 - Japan Society for Dementia Research Japan Society for Dementia Research Award Distribution and propagation of tau deposits in former professional boxers
  • 2021/08 - BPNP2021 presetantion award Association of brain tau accumulation and neuropsychiatric symptoms in chronic traumatic encephalopathy: A PET study with 18F-PM-PBB3(18F-APN-1607)
  • 2017 - Japanese Society of Psychiatry and Neurology Best Oral Presentation Award Delayed-Onset Psychosis following TBI is Associated with Tau Depositions in the Neocortex but Not with β-Amyloid Depositions: A Pet Study with [11C] PBB3 and [11C]PiB
  • 2011 - Association for the Scientific Study of Consciousness Best Poster Award On saving the self: Postdictive shifts of sense of agency by monetary gain and loss
Association Membership(s) (7):
Japan Society for Dementia Research ,  Japanese Society of Nuclear Medicine ,  The Japanse Society of Toxicology ,  THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY ,  Neuropsychology Association of Japan ,  JAPAN SOCIETY FOR HIGHER BRAIN DYSFUNCTION ,  The Japanese society of Psychiatry and Neurology
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