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J-GLOBAL ID：201901003470001679   Update date: Jun. 24, 2025

Takahata Keisuke

タカハタ ケイスケ | Takahata Keisuke
Affiliation and department：
Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology (QST) Advanced Neuroimaging Center

About Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology (QST) Advanced Neuroimaging Center


Job title： Chief Researcher
Other affiliations (2)：
  • Keio University School of Medicine  Department of Neuropsychiatry 
  • Ichikawa Medical Clinic
Research field  (2)： Psychiatry ,  Neuroscience - general
Research keywords  (15)： CTE ,  Long COVID ,  tauopathy ,  organophosphate poisoning ,  cognitive impairment ,  late-life psychosis ,  Positron Emission Tomography (PET) ,  Neuropsychology ,  遅発性脳障害 ,  器質性精神障害 ,  Tau PET imaging ,  PET ,  Chronic Traumatic Encephalopathy ,  Punch-drunk syndrome, Dementia Pugilistica ,  Traumatic brain injury
Research theme for competitive and other funds  (15)：
  • 2024 - 2028 中枢神経損傷による続発性タウオパチーの病態解明
  • 2022 - 2027 タウ・アミロイドPETおよび7テスラMRI/MRSによる中高年期精神疾患の層別化
  • 2024 - 2025 7TMRI・アミロイド・タウPETを用いた外傷性脳損傷後遺症・脳萎縮機序の解明
  • 2022 - 2025 スポーツ頭部外傷後遅発性脳障害に対するMRI・タウPETによる画像診断法の確立
  • 2021 - 2025 Investigation about underpinning neural mechanisms of sequelae and brain atrophy after brain injury
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Papers (116)：
  • Kosei Nakamura, Kenji Tagai, Hitoshi Shinotoh, Shigeki Hirano, Soichiro Kitamura, Hironobu Endo, Keisuke Takahata, Yuhei Takado, Ming-Rong Zhang, Kazunori Kawamura, et al. Concurrent Alzheimer's disease pathologies in Lewy body diseases affect cognition and glucose metabolism in the posterior cingulate gyrus: A multimodal PET study. Journal of Alzheimer’s Disease. 2025
  • Miho Suganami, Keisuke Takahata, Yu Mimura, Masahiro Yamamoto, Hiroyuki Uchida, Taro Muramatsu, Masaru Mimura. Impact of brain damage on moral judgment. Psychiatry and Clinical Neurosciences Reports. 2025
  • Ryoji Goto, Kiwamu Matsuoka, Yasuyuki Kimura, Yuko Kataoka, Masaki Oya, Kosei Hirata, Kenji Tagai, Keisuke Takahata, Chie Seki, Kazunori Kawamura, et al. Human biodistribution and radiation dosimetry of two novel α-synuclein PET tracers, 18F-SPAL-T-06 and 18F-C05-05. Scientific reports. 2025. 15. 1. 8640-8640
  • Yasuharu Yamamoto, Keisuke Takahata, Morinobu Seki, Shohei Okusa, Harutsugu Tatebe, Ryo Ueda, Hironobu Endo, Kenji Tagai, Sho Moriguchi, Shin Kurose, et al. SLC9A6 -Linked Parkinson Syndrome in Female Heterozygotes Is Associated With PET-Detectable Tau Pathology. Neurology Genetics. 2025
  • Yuki Momota, Shogyoku Bun, Jinichi Hirano, Kei Kamiya, Ryo Ueda, Yu Iwabuchi, Keisuke Takahata, Yasuharu Yamamoto, Toshiki Tezuka, Masahito Kubota, et al. Amyloid-β prediction machine learning model using source-based morphometry across neurocognitive disorders. Scientific Reports. 2024. 14. 1. 7633-7633
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MISC (143)：
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Books (10)：
  • やさしい高次脳機能障害用語事典
    ぱーそん書房 2018 ISBN:9784907095482
  • 精神科身体合併症マニュアル
    医学書院 2018 ISBN:9784260035453
  • 今日の精神疾患治療指針
    医学書院 2016 ISBN:9784260024846
  • 認知リハビリテーション実践ガイド
    医学書院 2015 ISBN:9784260021456
  • Dementia
    2012 ISBN:4521734391
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Lectures and oral presentations  (27)：
  • 神経変性疾患の前駆状態としての精神疾患 老年期精神障害と外傷性精神障害
    (神経心理懇話会 2024 2024)
  • 慢性外傷性脳症(CTE)のタウPET所見
    (第 43 回日本認知症学会学術集会 2024)
  • 新規TSPO-PETトレーサー18F-FEDACの脳内動態
    (第 64 回日本核医学会学術総会 2024)
  • 遅発性気分障害の神経病理学的病態:PETと剖検脳による検討
    (第43回躁うつ病の薬理・生化学的研究懇話会 2024)
  • 精神・神経臨床における脳核医学画像:臨床の基本から最新の進歩まで 精神神経疾患におけるPETを用いた病態可視化技術の開発と展望
    (第120回 日本精神神経学会学術総会 2024)
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Education (2)：
  • 2008 - 2012 Keio University PhD course
  • 1997 - 2003 Keio University School of Medicine
Professional career (2)：
  • PhD (Keio University Schools of Medicine)
  • MD (Keio University Schools of Medicine)
Work history (6)：
  • 2024/04 - 現在 National Institutes for Quantum Science and Technology (QST) Advances Neuroimaging Center, Sector for NeuroPsychiatric Disease Research Sector Leader
  • 2023/04 - 現在 Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology (QST) Department of Functional Brain Imaging
  • 2015/04 - 現在 National Institute of Radiological Sciences (NIRS) National Institutes for Quantum and Radiological Science and Technology (QST) Chiba, Japan Department of Functional Brain Imaging Research Researcher
  • 2012/04 - 2015/03 National Institute of Radiological Sciences (NIRS) National Institutes for Quantum and Radiological Science and Technology (QST) Chiba, Japan Department of Functional Brain Imaging Research PosDoc Reearcher
  • 2005/04 - 2008/03 Tachikawa Hospital Department of Psychiatry
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Committee career (3)：
  • 2022/04 - 現在 Psychiatry and Clinical Neurosciences Reports Psychiatry and Clinical Neurosciences Reports Journal Editor
  • 2021/08 - 現在 Neuropsychology Association of Japan councilor
  • 2021/11 - Japan Society of Higher Brain Dysfunction a representative
Awards (4)：
  • 2023/11 - Japan Society for Dementia Research Japan Society for Dementia Research Award Distribution and propagation of tau deposits in former professional boxers
  • 2021/08 - BPNP2021 presetantion award Association of brain tau accumulation and neuropsychiatric symptoms in chronic traumatic encephalopathy: A PET study with 18F-PM-PBB3(18F-APN-1607)
  • 2017 - Japanese Society of Psychiatry and Neurology Best Oral Presentation Award Delayed-Onset Psychosis following TBI is Associated with Tau Depositions in the Neocortex but Not with β-Amyloid Depositions: A Pet Study with [11C] PBB3 and [11C]PiB
  • 2011 - Association for the Scientific Study of Consciousness Best Poster Award On saving the self: Postdictive shifts of sense of agency by monetary gain and loss
Association Membership(s) (7)：
Japan Society for Dementia Research ,  Japanese Society of Nuclear Medicine ,  The Japanse Society of Toxicology ,  THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY ,  Neuropsychology Association of Japan ,  JAPAN SOCIETY FOR HIGHER BRAIN DYSFUNCTION ,  The Japanese society of Psychiatry and Neurology
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