Yokoi Satoshi

Research field (1)： Neurology

Research keywords (5)： Frontotemporal lober degeneration , RNA metabolism , spine morphology , Amyotrophic lateral sclerosis , FUS

Research theme for competitive and other funds (6)：

2022 - 2025 Study of synaptic pahtology caused by FUS in amyotrophic lateral sclerosis
2022 - 2025 Development of neuronal aggregates-targeted therapeutics
2022 - 2024 遠位型遺伝性運動ニューロパチー7型の病態解明と病態抑止療法の開発
2022 - 2024 運動ニューロン疾患の初期軸索病態の解明
2021 - 2023 Wide-field Ca imaging and trans-omics for mouse model of Lewy body disease

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Papers (42)：

Yuki Fukami, Masahiro Iijima, Haruki H Koike, Satoru Yagi, Soma Furukawa, Naohiro Mouri, Jun Ouchida, Ayuka Murakami, Madoka Iida, Satoshi Yokoi, et al. Autoantibodies Against Dihydrolipoamide S-Acetyltransferase in Immune-Mediated Neuropathies. Neurology(R) neuroimmunology & neuroinflammation. 2024. 11. 2. e200199
Satoshi Yokoi, Takuji Ito, Kentaro Sahashi, Masahiro Nakatochi, Ryoichi Nakamura, Genki Tohnai, Yusuke Fujioka, Shinsuke Ishigaki, Tsuyoshi Udagawa, Yuishin Izumi, et al. The SYNGAP1 3'UTR variant in ALS patients causes aberrant SYNGAP1 splicing and dendritic spine loss by recruiting HNRNPK. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022. 42. 47. 8881-8896
Takashi Ando, Takahiko Sato, Shingo Kurahashi, Yuka Kawaguchi, Yusuke Kagaya, Yukiyasu Ozawa, Satoko Hirano, Yoji Goto, Kazuo Mano, Satoshi Yokoi, et al. A case of sporadic late-onset nemaline myopathy with monoclonal gammopathy of undetermined significance: long-term observation of neurological symptoms after autologous stem-cell transplantation. NAGOYA JOURNAL OF MEDICAL SCIENCE. 2021. 83. 3. 641-647
Takashi Ando, Takahiko Sato, Shingo Kurahashi, Yuka Kawaguchi, Yusuke Kagaya, Yukiyasu Ozawa, Satoko Hirano, Yoji Goto, Kazuo Mano, Satoshi Yokoi, et al. A case of sporadic late-onset nemaline myopathy with monoclonal gammopathy of undetermined significance: long-term observation of neurological symptoms after autologous stem-cell transplantation. Nagoya journal of medical science. 2021. 83. 3. 641-647
Yokoi Satoshi, Ito Takuji, Sahashi Kentaro, Nakamura Ryoichi, Ishigaki Shinsuke, Atsuta Naoki, Katsuno Masahisa, Okada Yohei, Sobue Gen. ALSコホート由来のSynGAP 3'-UTRの変異はFUS-SynGAP mRNAの調節とスパインの形成に異常を引き起こす(SynGAP 3'UTR mutation from ALS cohort causes aberrant FUS-SynGAP mRNA regulation and spine formation). 臨床神経学. 2020. 60. Suppl. S480-S480

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MISC (34)：

宇田川剛, 宇田川剛, 藤岡祐介, 田中基樹, 本田大祐, 横井聡, 衣斐大祐, 永井拓, 山田清文, 渡辺宏久, et al. FUSはGluA1mRNA安定性の調節を介してシナプス機能及びFTLD/ALS様行動を制御する. 日本生化学会大会(Web). 2015. 88th
宇田川剛, 藤岡祐介, 田中基樹, 本田大祐, 横井聡, 衣斐大祐, 衣斐大祐, 永井拓, 永井拓, 山田清文, et al. FUSはGluR1 mRNAの安定化を介してAMPA受容体機能,及びALS/FTLD関連行動を制御する. 日本RNA学会年会要旨集. 2014. 16th
渡辺宏久, 宇田川剛, 藤岡祐介, 本田大祐, 横井聡, 石垣診佑, 田中基樹, 曽我部正博, 岡戸晴生, 祖父江元. FUSはGluA1mRNA安定性の調節を介してシナプス機能及びFTLD様行動を制御する. Dementia Japan. 2014. 28. 4
安井敬三, 中井紀嘉, 荒木周, 川畑和也, 山田晋一郎, 横井聡, 大山健, 眞野智生, 満間典雅, 長谷川康博, et al. 一過性脳虚血発作における急性期拡散強調画像陽性例の頻度と臨床特徴. 脳卒中. 2013. 35. 5. 328-336
Keizo Yasui, Noriyoshi Nakai, Amane Araki, Kazuya Kawabata, Shin-ichiro Yamada, Satoshi Yokoi, Ken Ooyama, Tomoo Mano, Norimasa Mitsuma, Yasuhiro Hasegawa, et al. The Prevalence and Clinical Significance of Ischemic Lesions on Diffusion-Weighted Image in Patients with Transient Ischemic Attack. CEREBROVASCULAR DISEASES. 2013. 36. 29-30

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