Research theme for competitive and other funds (9):
2024 - 2027 孤発性ALS病態を反映した動物モデル作成とTDP-43凝集抑制療法の開発
2024 - 2026 ALSに関連する運動ニューロン周囲オリゴデンドロサイトの機能と役割の解明
2022 - 2025 Therapeutic development against protein aggregation
2022 - 2025 Study of synaptic pahtology caused by FUS in amyotrophic lateral sclerosis
2022 - 2025 Development of neuronal aggregates-targeted therapeutics
2022 - 2024 遠位型遺伝性運動ニューロパチー7型の病態解明と病態抑止療法の開発
2022 - 2024 運動ニューロン疾患の初期軸索病態の解明
2021 - 2023 Wide-field Ca imaging and trans-omics for mouse model of Lewy body disease
2020 - 2022 Study of pathogenic mechanism of amyotrophic lateral sclerosis through excessive recrutiment of RNA-binding protein FUS
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Papers (44):
Yuki Fukami, Masahiro Iijima, Haruki H Koike, Satoru Yagi, Soma Furukawa, Naohiro Mouri, Jun Ouchida, Ayuka Murakami, Madoka Iida, Satoshi Yokoi, et al. Autoantibodies Against Dihydrolipoamide S-Acetyltransferase in Immune-Mediated Neuropathies. Neurology(R) neuroimmunology & neuroinflammation. 2024. 11. 2. e200199
Yohei Iguchi, Yuhei Takahashi, Jiayi Li, Kunihiko Araki, Yoshinobu Amakusa, Yu Kawakami, Kenta Kobayashi, Satoshi Yokoi, Masahisa Katsuno. IκB kinase phosphorylates cytoplasmic TDP-43 and promotes its proteasome degradation. The Journal of cell biology. 2024. 223. 2
Satoshi Yokoi, Takuji Ito, Kentaro Sahashi, Masahiro Nakatochi, Ryoichi Nakamura, Genki Tohnai, Yusuke Fujioka, Shinsuke Ishigaki, Tsuyoshi Udagawa, Yuishin Izumi, et al. The SYNGAP1 3'UTR variant in ALS patients causes aberrant SYNGAP1 splicing and dendritic spine loss by recruiting HNRNPK. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022. 42. 47. 8881-8896
Takashi Ando, Takahiko Sato, Shingo Kurahashi, Yuka Kawaguchi, Yusuke Kagaya, Yukiyasu Ozawa, Satoko Hirano, Yoji Goto, Kazuo Mano, Satoshi Yokoi, et al. A case of sporadic late-onset nemaline myopathy with monoclonal gammopathy of undetermined significance: long-term observation of neurological symptoms after autologous stem-cell transplantation. NAGOYA JOURNAL OF MEDICAL SCIENCE. 2021. 83. 3. 641-647
Keizo Yasui, Noriyoshi Nakai, Amane Araki, Kazuya Kawabata, Shin-ichiro Yamada, Satoshi Yokoi, Ken Ooyama, Tomoo Mano, Norimasa Mitsuma, Yasuhiro Hasegawa, et al. The Prevalence and Clinical Significance of Ischemic Lesions on Diffusion-Weighted Image in Patients with Transient Ischemic Attack. CEREBROVASCULAR DISEASES. 2013. 36. 29-30