- 2022 - 2026 The critical role of ATR activation in the process of therapy-induced senescence
- 2022 - 2024 機能獲得型変異p53が制御する癌幹細胞化の解明と治療戦略の確立
- 2020 - 2023 Establishment of new selection system for adjuvant chemotherapy of colorectal cancer
- 2018 - 2020 RNA involvement in the process of chemotherapy-induced DNA replication stress
- 2017 - 2020 Molecular mechanism of therapy-induced senescence caused by replicative stress
- 2017 - 2020 Molecular mechanisms of cytokinesis completion and cell fate decision after cytokinesis failure
- 2015 - 2020 Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells
- 2016 - 2019 Elucidation of molecular mechanisms of and development of combined therapy with immune checkpoint inhibitors for digestive tract cancer
- 2014 - 2017 Gemonic alteration, molecular subtypes and drug sensitivity in breast cancer
- 2014 - 2017 Investigation of chemoradiation sensitivity based on the DNA repair mechanism in esophageal carcinoma
- 2013 - 2016 Novel molecular targeting strategy against chromosomal maintenance factor FANCJ
- 2013 - 2016 Chromosomal dynamics and development of novel therapy in gastrointestinal tract cancer
- 2013 - 2016 Establishment of the new therapy based on inflammatory mediator and DNA methylation in colorectal cancer
- 2013 - 2016 The analysis of the spindle checkpoint protens and the application to the new molecular targetted therapy for colorectal cancer.
- 2012 - 2016 DNA mismatch repair gene analysis predicts the response to anticancer drug sensitivity in gastrointestinal cancers for tailored therapy.
- 2011 - 2013 Molecular mechanisms of hormone sensitivity of hormone receptor-positive breast cancer and their application for individual treatment
- 2011 - 2013 A systematic study of the disorders in the spindle assembly checkpoint genes in colorectal cancer and its application to molecular targeted therapy
- 2009 - 2011 Genomic instability in the absence of FANCJ and its possible contribution to tumorigenesis
- 2005 - 2009 Functional analysis of Fanconi anemia genes that are involved in chromosomal stability and tumor prevention
- 2007 - 2008 Regulation of the ubiquitin system by checkpoint kinases in response to stalled replication forks
- 2007 - 2008 Molecular mechanism of large genome deletion induced byDisrupting BRCA1-related gene, FA-J.
- 2005 - 2006 Induction of single DNA double strand break in animal cell genome and its monitoring methodology
- 2005 - 2006 ファンコニ貧血遺伝子FA-D2と家族性乳ガン遺伝子Brca2との相互作用の再検討
- 2003 - 2004 Physical monitoring of repair process of chromosomal double stand break induced by simultaneous nuclear introduction of I-SceI endonuclease
- 2000 - 2004 Functional analysis of genes involved in maintenance of chromosome stability and homologous recombination
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