Rchr
J-GLOBAL ID：201901003941909013   Update date: Nov. 16, 2024

Sekizawa Shin-ichi

セキザワ シンイチ | Sekizawa Shin-ichi
Affiliation and department：
-

About -


Research field  (1)： Physiology
Research keywords  (1)： Physiology, Respiration, Cardiovasular System, Electrophysiology, Toxicology, Brainstem, Nucleus Tractus Solitarius, Spinal Trigeminal Nucleus, Ethmoidal nerves, Trigeminal nerves, Vagus nerves, Superior Laryngeal Nerves,
Research theme for competitive and other funds  (4)：
  • 2022 - 2026 Are changes in the properties of nucleus tractus solitarius inhibitory interneurons during postnatal development a risk factor for sudden infant death syndrome?
  • 2021 - 2024 Research on novel therapeutic targets for nasal allergy
  • 2021 - 2024 中枢神経系に対する新規安全性薬理試験評価法に関する研究
  • 2020 - 2023 自律神経とその幹細胞に着目した抗がん剤の遅発性心毒性の病態解明
Papers (68)：
  • Sara Brownell, Carly Busch, Katelyn Cooper. Undergraduates have few science instructor role models with concealable stigmatized identities. Physiology. 2024. 39. S1
  • Akitoshi Chikamoto, Ryota Tochinai, Shin-Ichi Sekizawa, Masayoshi Kuwahara. Plasticity occurs in a specific phenotype of neurons in the nucleus tractus solitarius of dystrophin gene-mutated rats. The European journal of neuroscience. 2023
  • Ryota Tochinai, Koichi Kimura, Takeru Saika, Wataru Fujii, Hiroyuki Morita, Koki Nakanishi, Yoshiharu Tsuru, Shin-Ichi Sekizawa, Keitaro Yamanouchi, Masayoshi Kuwahara. Ivabradine ameliorates cardiomyopathy progression in a Duchenne muscular dystrophy model rat. Experimental animals. 2023. 73. 2. 145-153
  • Ryota Tochinai, Yoshiyasu Nagashima, Shin-Ichi Sekizawa, Masayoshi Kuwahara. Anti-tumor and cardiotoxic effects of microtubule polymerization inhibitors: The mechanisms and management strategies. Journal of applied toxicology : JAT. 2023
  • Haruka Orihara, Min Ma, Yoshiyasu Nagashima, Ryota Tochinai, Shin-Ichi Sekizawa, Daiki Kato, Masahiro Shinada, Susumu Aoki, Naoki Fujita, Takayuki Nakagawa, et al. Co-administration of JQ1, a bromodomain-containing protein 4 inhibitor, enhances the antitumor effect of combretastatin A4, a microtubule inhibitor, while attenuating its cardiotoxicity. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023. 160. 114353-114353
ｍore...
MISC (36)：
  • Mahipal Singh, Alexis Irving, Abosede Abolude, Adel Moawad, Xiaoling Ma, Brou Kouakou. PSXIII-14 Effect of melatonin supplementation during in vitro embryo culture on cleavage rates following in vitro maturation and fertilization of bovine oocytes. Journal of Animal Science. 2024. 102. Supplement_3. 717-717
  • Airi Tanaka, Cong HU, Ryota Tochinai, Shin-Ichi Sekizawa, Masayoshi Kuwahara. H3 Receptor Expression in the Spinal Trigeminal Nucleus Caudalis in a Rat Model of Allergic Rhinitis. Physiology. 2024. 39. S1
  • TOCHINAI Ryota, OKUBO Yusuke, MA Min, TAKANO Tamami, KOJIMA Shunpei, OHARA Ibuki, NISHIMURA Takuya, TAQUAHASHI Yuhji, KITAJIMA Satoshi, HIRABAYASHI Yoko, et al. Challenges in developing a wearable device for rats to contribute to toxicology research. Annual Meeting of the Japanese Society of Toxicology. 2024. 51.1. P-172
  • NAGASHIMA Yoshiyasu, WATANABE Sou, CHIKAMOTO Akitoshi, TOCHINAI Ryota, SEKIZAWA Shin-ichi, KUWAHARA Masayoshi. Study on heart rate variability indexes for Safety Pharmacology assessments of drug-induced undesirable effects on the central nervous systems. Annual Meeting of the Japanese Society of Toxicology. 2024. 51.1. P-75S
  • 関澤 信一. Biological Academic Topics 鼻アレルギー時のくしゃみ反射増悪に延髄は関与するか?. アレルギーの臨床. 2023. 43. 9. 730-733
ｍore...
Books (1)：
  • バイオロジクスの開発と品質・安全性確保
    エル・アイ・シー 2018
Education (2)：
  • 1992 - 1996 The University of Tokyo Graduate School of Agricultural and Life Sciences Department of Veterinary Medical Sciences
  • 1986 - 1992 The University of Tokyo College of Arts and Sciences
Work history (3)：
  • 2016/10 - 現在 東京大学大学院農学生命科学研究科
  • 2012/02 - 2016/09 (独)医薬品医療機器総合機構
  • 2001/04 - 2012/01 カリフォルニア大学デイビス校
Awards (3)：
  • 2011 - University of California Davis Academic Federation Research Travel Award High fat diet increases blood pressure and blunts 2nd-order baroreceptive neuronal responses to leptin and melanocyte-stimulating hormone (MSH) in the nucleus tractus solitarius (NTS).
  • 2009 - University of California Davis Academic Federation Research Travel Award
  • 2009 - American Physiological Society A travel award recipient for the IUPS 2009 Congress Neuronal phenotype specific membrane response via post-synaptic metabotropic glutamate receptors (mGluRs) on second-order baroreceptor neurons of the rat nucleus tractus solitarius (NTS).
Association Membership(s) (3)：
THE JAPANESE SOCIETY OF TOXICOLOGY ,  THE JAPANESE SOCIETY OF VETERINARY SCIENCE ,  THE PHYSIOLOGICAL SOCIETY OF JAPAN
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