Rchr
J-GLOBAL ID:201901005380014600   Update date: Apr. 17, 2024

Murai Shin

Murai Shin
Affiliation and department:
Job title: Lecturer
Research field  (1): Medical biochemistry
Research theme for competitive and other funds  (3):
  • 2023 - 2024 IL-33放出機構の解明に向けた細胞分泌実時間イメージング解析
  • 2020 - 2022 敗血症モデルにおける計画的ネクローシスのFRETイメージング
  • 2016 - 2019 Live cell imaging of regulated necrosis
Papers (21):
  • Yuka Inaba, Emi Hashiuchi, Hitoshi Watanabe, Kumi Kimura, Yu Oshima, Kohsuke Tsuchiya, Shin Murai, Chiaki Takahashi, Michihiro Matsumoto, Shigetaka Kitajima, et al. The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice. Nature Communications. 2023. 167
  • Shin Murai, Kanako Takakura, Kenta Sumiyama, Kenta Moriwaki, Kenta Terai, Sachiko Komazawa-Sakon, Takao Seki, Yoshifumi Yamaguchi, Tetuo Mikami, Kimi Araki, et al. Generation of transgenic mice expressing a FRET biosensor, SMART, that responds to necroptosis. Communications Biology. 2022. 5. 1. 1331-1331
  • Shin Murai, Kanako Takakura, Kenta Sumiyama, Kenta Moriwaki, Kenta Terai, Sachiko Komazawa-Sakon, Yoshifumi Yamaguchi, Tetuo Mikami, Kimi Araki, Masaki Ohmuraya, et al. A FRET biosensor, SMART, monitors necroptosis in renal tubular epithelial cells in a cisplatin-induced kidney injury model. 2022
  • Hiroyasu Nakano, Shin Murai, Kenta Moriwaki. Regulation of the release of damage-associated molecular patterns from necroptotic cells. The Biochemical journal. 2022. 479. 5. 677-685
  • Osamu Nakabayashi, Hirotaka Takahashi, Kenta Moriwaki, Sachiko Komazawa-Sakon, Fumiaki Ohtake, Shin Murai, Yuichi Tsuchiya, Yuki Koyahara, Yasushi Saeki, Yukiko Yoshida, et al. MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL. Communications biology. 2021. 4. 1. 80-80
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MISC (42):
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Books (1):
  • 筋収縮「分子生物学ノート」
    学会出版センター 1995
Lectures and oral presentations  (72):
  • SMART Tg マウスを用いた急性腎障害によるネクロプトーシスの in vivo FRET 解析
    (第30回日本Cell Death学会学術集会 2022)
  • SMART Tgマウス由来細胞を用いたネクロプトーシスのライブセルイメージング
    (第29回日本Cell Death学会学術集会 2021)
  • A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs
    (第73回 東邦医学会総会 2019)
  • ネクロプトーシスのタイムラプスイメージング
    (理研シンポジウム「細胞システムの動態と論理IX」 2019)
  • FRETバイオセンサーによるネクロプトーシス実行の1細胞イメージング
    (日本生化学会大会プログラム・講演要旨集 2018)
more...
Work history (2):
  • 2023/08 - 現在 Toho University Faculty of Medicine School of Medicine Lecturer
  • 2007/04 - 2023/07 Toho University Faculty of Medicine School of Medicine Assistant Professor
Awards (2):
  • 2019/11 - 東邦医学会 東邦医学会賞 A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs
  • 2017/07 - 日本Cell Death学会 最優秀ポスター賞 SMARTによるネクロプトーシス進行の継時的解析
Association Membership(s) (3):
日本CellDeath学会 ,  Japanese Society of Mammalian Ova Research ,  Japanese Society of Developemental Biologists
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