MATSUNAGA Hayato

Affiliation and department：

Research field (3)： Cell biology , Neuroscience - general , Functional biochemistry

Research theme for competitive and other funds (7)：

2019 - 2022 Mechanisms of localisation and function of metabotropic glutamate receptors regulated by the synaptic membrane protein ELFN
2014 - 2017 Reproduction of chronic pain model through a reconstitution of neuronal circuit components including LPA priming and iPS cells, and its application for drug discovery
2013 - 2016 Reprogramming of a neuroprotective phenotype in recipient cells via a shuttle action of prothymosin-alpha, a multifunctional damage-associated molecular patterns between nuclear and extracellular.
2013 - 2016 Innate immunity regulation by prothymosin alpha -mimetics
2011 - 2012 Screening of binary neuroprotective DAMPs activity

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Papers (30)：

Stephanie Efthymiou, Wenyan Han, Muhammad Ilyas, Jun Li, Yichao Yu, Marcello Scala, Nancy T. Malintan, Muhammad Ilyas, Nikoleta Vavouraki, Kshitij Mankad, et al. Human mutations in SLITRK3 implicated in GABAergic synapse development in mice. Frontiers in Molecular Neuroscience. 2024
Minoru Hatayama, Kei-ichi Katayama, Yukie Kawahara, Hayato Matsunaga, Noriko Takashima, Yoshimi Iwayama, Yoshifumi Matsumoto, Akinori Nishi, Takeo Yoshikawa, Jun Aruga. SLITRK1-mediated noradrenergic projection suppression in the neonatal prefrontal cortex. Communications Biology. 2022. 5. 1
Kei-Ichi Katayama, Naoko Morimura, Katsunori Kobayashi, Danielle Corbett, Takehito Okamoto, Veravej G Ornthanalai, Hayato Matsunaga, Wakako Fujita, Yoshifumi Matsumoto, Takumi Akagi, et al. Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation. iScience. 2022. 25. 7. 104604-104604
Misato Ichise, Kazuto Sakoori, Kei-ichi Katayama, Naoko Morimura, Kazuyuki Yamada, Hiroki Ozawa, Hayato Matsunaga, Minoru Hatayama, Jun Aruga. Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics. FRONTIERS IN MOLECULAR NEUROSCIENCE. 2022. 15
Hayato Matsunaga, Sebok Kumar Halder, Hiroshi Ueda. Annexin A2 Flop-Out Mediates the Non-Vesicular Release of DAMPs/Alarmins from C6 Glioma Cells Induced by Serum-Free Conditions. Cells. 2021. 10. 3

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MISC (36)：

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Books (5)：

Neuropeptides in Neuroprotection and Neuroregeneration
CRC Press 2019 ISBN:0367381230
研究成果を薬につなげるアカデミア創薬の戦略と実例
羊土社 2014 ISBN:9784758103367
ストレス科学事典
日本ストレス学会;パブリックヘルスリサーチセンター・実務教育出版 2011 ISBN:9784788960848
生体の科学 Vol.58 No.5
医学書院 2007
Clinical Neuroscience Vol.24 (06年) 02月号グルタミン受容体分子機構から治療戦略へ
中外医学社 2006

Lectures and oral presentations (5)：

プロサイモシンα由来脳梗塞保護ペプチドの創薬研究
(日本薬理学会西南部会プログラム/抄録集 2013)
Mechanism of non-vesicular release of neuroprotective DAMPs
(日本薬理学会年会 2013)
神経保護性DAMPs:プロサイモシンαの非小胞性遊離機構
(日本薬理学会西南部会プログラム/抄録集 2012)
神経可塑性と精神疾患~樹上突起伸展作用を持つ物質探索~
(日本薬学会九州支部大会講演要旨集 2003)
グルコース脳室内投与によるトリメチルスズ神経毒性保護
(日本薬理学会近畿部会プログラム/妙録集 2001)

Professional career (1)：

博士(薬学) (長崎大学)

Association Membership(s) (4)：

THE JAPAN NEUROSCIENCE SOCIETY , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE PHARMACOLOGICAL SOCIETY

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