Rchr
J-GLOBAL ID:201901006553167160   Update date: Jan. 25, 2021

Osamu Nakabayashi

ナカバヤシ オサム | Osamu Nakabayashi
Affiliation and department:
Research field  (1): Molecular biology
Research theme for competitive and other funds  (6):
  • 2020 - 2023 膜透過性ペプチドを用いた細胞死抑制による新たな抗敗血症薬の提案
  • 2017 - 2019 Live imaging of necroptosis and the release of DAMPs
  • 2016 - 2018 Elucidation for Histone induced cell death in sepsis
  • 2014 - 2015 Gene-trap法を用いたネクロプトーシス実行遺伝子の同定
  • 2013 - 2014 SPB構成因子Cdc31のDNA複製開始における制御機構の解析
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Papers (8):
  • Osamu Nakabayashi, Hirotaka Takahashi, Kenta Moriwaki, Sachiko Komazawa-Sakon, Fumiaki Ohtake, Shin Murai, Yuichi Tsuchiya, Yuki Koyahara, Yasushi Saeki, Yukiko Yoshida, et al. MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL. Communications biology. 2021. 4. 1. 80-80
  • Nakano H, Murai S, Yamaguchi Y, Shirasaki Y, Nakabayashi O, Yamazaki S. Development of novel methods that monitor necroptosis and the release of DMAPs at the single cell resolution. Cell Stress. 2019. 3. 66-69
  • Shin Murai†, Yoshifumi Yamaguchi, Yoshitaka Shirasaki, Mai Yamagishi, Ryodai Shindo, Joanne M. Hildebrand, Ryosuke Miura, Osamu Nakabayashi†, Mamoru Totsuka, Taichiro Tomida†, et al. A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs. Nature Communications. 2018. 9. 4457
  • Xuehua Piao, Soh Yamazaki, Sachiko Komazawa-Sakon, Sanae Miyake, Osamu Nakabayashi, Takeyuki Kurosawa, Tetsuo Mikami, Minoru Tanaka, Nico Van Rooijen, Masaki Ohmuraya, et al. Depletion of myeloid cells exacerbates hepatitis and induces an aberrant increase in histone H3 in mouse serum. Hepatology. 2017. 65. 1. 237-252
  • Tsuchiya Y, Nakabayashi O†, Nakano H†. FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP. International Journal of Molecular Sciences. 2015. 16. 12. 30321-30341
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Books (1):
  • 移行データなし
    Perspective in comparative endocrinology: unity and diversity 2001
Lectures and oral presentations  (27):
  • MIND BOMB-2はcFLIP<SUB>L</SUB>を安定化することにより細胞死を抑制する
    (第28回日本Cell Death学会学術集会 2019)
  • Single cell analysis of necroptosis execution by FRET biosensor
    (2018)
  • MIND BOMB-2はcFLIPLを安定化することにより細胞死を抑制する
    (第91回日本生化学会大会 2018)
  • MIND BOMB-2はcFLIPLをユビキチン化することで細胞死を抑制する
    (2017年度 生命科学系学会合同年次大会 2017)
  • ネクロプトーシスをモニターするFRETバイオセンサーによるDAMPs放出メカニズムの解明
    (2017年度 生命科学系学会合同年次大会 2017)
more...
Work history (1):
  • 2007/04/01 - 現在 Faculty of Medicine Faculty of Medicine School of Medicine
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