Research keywords (4):
Pediatric hematology and oncology
, Relapsed acute lymphoblastic leukemia
, Leukemia
, Cancer Genomics
Research theme for competitive and other funds (8):
2019 - 2023 Genome-wide CRISPR/Cas9 screening for drug target discovery in neuroblastoma
2012 - 2014 Hematopoietic stem cell potential is propagated by human pluripotent stem cell-derived endothelial stroma
2011 - 2013 Analysis of pathophysiology and identification of the causative gene(s) of primary immunodeficiency with B, NK, dendritic cell deficiency
2011 - 2012 疾患特異的iPS細胞を用いた細網異形成症の病態解析
2010 - 2012 Research for developing of a screening method for the congenital immunodeficiency by KREC/TREC to apply the method to the pathologic analysis
2010 - 2012 Recapitulation of phenotypes and discovery of a novel treatment with disease-specific human ES/ iPS cells from various hereditary diseases
2010 - 2011 自己識別機構の破綻をきたす免疫不全症の病態解明と原因遺伝子同定
2009 - 2010 Development of easy and cost-effective mass-screening of severe combined immunodeficiency using neonatal guthrie cards.
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Papers (58):
Kyohei Isshiki, Makiko Mori, Tomoya Irikura, Takahiro Ishikawa, Mamoru Honda, Ryota Kaneko, Yuichi Mitani, Hirohito Kubota, Kohei Fukuoka, Koichi Oshima, et al. Long-term efficacy and safety profile of splenectomy for pediatric chronic immune thrombocytopenia. International journal of hematology. 2023. 117. 5. 774-780
Mamoru Honda, Arakawa Yuki, Hosokawa Takahiro, Oyama Chigusa, Mitani Yuichi, Mori Makiko, Kohei Fukuoka, Oshima Koichi, Tanami Yutaka, Ishimaru Tetsuya, et al. Predictive risk score of respiratory complications in children with mediastinal tumors: A case-control study. Cancer medicine. 2022
Koichi Oshima, Hossein Khiabanian, Ana Carolina da Silva Almeida, Gannie Tzoneva, Francesco Abate, Alberto Ambesi-Impiombato, Marta Sanchez-Martin, Zachary Carpenter, Alexander Penson, Arianne Perez-Garcia, et al. Mutational Landscape, Clonal Evolution Patterns and Role of RAS Mutations in Relapsed Acute Lymphoblastic Leukemia. BLOOD. 2016. 128. 22