Hatipoglu Omer Faruk

Affiliation and department：
Job title： Assistant professor

Research field (1)： Molecular biology

Research keywords (6)： ADAMTS proteases , microRNA , MMP , Aortic Dissection , Osteoarthritis , Cancer and Angiognesis

Research theme for competitive and other funds (10)：

2024 - 2027 Development of control method for inflammaging by targeting advanced glycation end products
2024 - 2027 変形性膝関節症の疼痛におけるTNFαの役割と血漿タンパクHRGの疼痛抑制効果
2023 - 2026 運動介入による再生、修復促進効果の新しい機序の解析研究
2021 - 2024 Homeostatic effect of improvement candidate drug targeting IL-33
2023 - 2024 Elucidation of the mechanism of histamine-induced angiogenesis via IL-33 and ST2L in chronic inflammation

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Papers (46)：

Masahiro Watanabe, Takao Toyomura, Hidenori Wake, Takashi Nishinaka, Omer Faruk Hatipoglu, Hideo Takahashi, Masahiro Nishibori, Shuji Mori. Cationic ribosomal proteins can inhibit pro-inflammatory action stimulated by LPS+HMGB1 and are hindered by advanced glycation end products. Biotechnology and applied biochemistry. 2023
Takashi Nishinaka, Omer Faruk Hatipoglu, Hidenori Wake, Masahiro Watanabe, Takao Toyomura, Shuji Mori, Masahiro Nishibori, Hideo Takahashi. Different modulation of STING/TBK1/IRF3 signaling by advanced glycation end products. Archives of biochemistry and biophysics. 2023. 750. 109808-109808
Takao Toyomura, Masahiro Watanabe, Hidenori Wake, Takashi Nishinaka, Omer Faruk Hatipoglu, Hideo Takahashi, Masahiro Nishibori, Shuji Mori. Glycolaldehyde-derived advanced glycation end products promote macrophage proliferation via the JAK-STAT signaling pathway. Molecular Biology Reports. 2023. 50. 7. 5849-5858
Omer Faruk Hatipoglu, Takashi Nishinaka, Masahiro Nishibori, Masahiro Watanabe, Takao Toyomura, Shuji Mori, Kursat Oguz Yaykasli, Hidenori Wake, Hideo Takahashi. Histamine promotes angiogenesis through a histamine H1 receptor-PKC-VEGF-mediated pathway in human endothelial cells. Journal of pharmacological sciences. 2023. 151. 4. 177-186
Takashi Nishinaka, Omer Faruk Hatipoglu, Hidenori Wake, Masahiro Watanabe, Takao Toyomura, Shuji Mori, Masahiro Nishibori, Hideo Takahashi. Glycolaldehyde-derived advanced glycation end products suppress STING/TBK1/IRF3 signaling via CD36. Life sciences. 2022. 310. 121116-121116

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MISC (22)：

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Patents (2)：

Books (3)：

Chapter name:Non-invasive molecular markers in gynecologic cancers. Book name:Biomarkers for early detection of familial breast cancer
CRC Press 2015 ISBN:9781466569386
Chapter name:A concise review of molecular pathology of breast cancer. Book name:Micrornas as therapeutic targets in human breast cancer
intechopen 2014 ISBN:9789535120308
Chapter name:Pharmacogenomics in Acute Myeloid Leukemia. Book name:Omics for personalized medicine
Springer 2013 ISBN:9788132211846

Lectures and oral presentations (4)：

Histamine promotes tube formation of vascular endothelial cells
(Japan Basic and Clinical Pharmacology 2022)
Regulation of STING signal by advanced glycation end products
(Japan Basic and Clinical Pharmacology 2022)
Antioxidant potential of histidine-rich glycoprotein contributes to improvement of sepsis pathophysiology
(Japan Basic and Clinical Pharmacology 2022)
Function control of adhesion molecule CD44 and its role in aortic aneurysm / aortic dissection
(49th Annual Scientific Meeting of the Japanese Society for Circulation Research .)

Education (2)：

2005 - 2009 Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences PhD
2003 - 2005 Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences master course

Professional career (1)：

Ph.D. (Okayama University)

Awards (4)：

2016 - Medical Genetics Conference Best Poster Award
2012 - Okayama University International Training Program
2010 - JSPS Postdoctoral Fellowship
2003 - JAPANESE GOVERNMENT (MEXT) SCHOLARSHIP

Association Membership(s) (3)：

日本生化学会 , 日本分子生物学会 , 日本薬理学学会

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