Rchr
J-GLOBAL ID:201901007014032720   Update date: Jul. 23, 2024

Hazama Hisanao

ハザマ ヒサナオ | Hazama Hisanao
Affiliation and department:
Research field  (5): Analytical chemistry ,  Chemical biology ,  Biomedical engineering ,  Medical systems ,  Tumor diagnostics and therapeutics
Research keywords  (8): Mass spectrometry imaging ,  Laser ionization mass spectrometry ,  Optical measurement of tooth hardness ,  Photodynamic diagnosis and therapy ,  Healthy life expectancy ,  Opto-biomechanics ,  Tissue optics ,  Laser
Research theme for competitive and other funds  (11):
  • 2021 - 2024 Development of single-cell mass spectrometry imaging techniques to analyze drug-cell interactions
  • 2020 - 2023 有機溶存物質のエアロミセル化・水マトリックス支援ソフトイオン化による直接質量分析
  • 2020 - 2023 Ultra-early detection of gastrointestinal cancer and establishment of on-site adaptive diagnostic methods toward standardization of laser ESD
  • 2019 - 2021 Development of Computational Clinical Trial Mehtod for Laser Medicine
  • 2016 - 2019 Development of infrared laser ionization techniques for high throughput mass spectrometry of membrane proteins
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Papers (145):
  • Sota Kondo, Yutaka Tomioka, Naohiro Fujimoto, Atsushi Mine, Satoshi Yamaguchi, Saeko Okumura, Hiroaki Tanimoto, Kenzo Yasuo, Kazushi Yoshikawa, Kazuyo Yamamoto, et al. Theoretical study on the mechanism of dentin hardness measurement using a tooth hardness measuring device with a light-emitting diode. Nippon Laser Igakkaishi (in press). 2024
  • Sochi J. Ogbonna, Katsuyoshi Masuda, Hisanao Hazama. The effect of fluence rate and wavelength on the formation of protoporphyrin IX photoproducts. Photochemical and Photobiological Sciences (in press). 2024
  • Sota Kondo, Yutaka Tomioka, Naohiro Fujimoto, Atsushi Mine, Satoshi Yamaguchi, Saeko Okumura, Hiroaki Tanimoto, Kenzo Yasuo, Kazushi Yoshikawa, Kazuyo Yamamoto, et al. Mechanism of dentin hardness measurements using a dentin hardness measuring device with a light-emitting diode. Journal of Biomedical Optics. 2024. 29. 02. 025002-1-025002-14
  • Sochi J. Ogbonna, William Y. York, Takahiro Nishimura, Hisanao Hazama, Hideo Fukuhara, Keiji Inoue, Kunio Awazu. Increased fluorescence observation intensity during the photodynamic diagnosis of deeply located tumors by fluorescence photoswitching of protoporphyrin IX. Journal of Biomedical Optics. 2023. 28. 5. 055001-1-055001-15
  • Sota Kondo, Hisanao Hazama, Yutaka Tomioka, Atsushi Mine, Satoshi Yamaguchi, Saeko Okumura, Hiroaki Tanimoto, Kenzo Yasuo, Kazushi Yoshikawa, Kazuyo Yamamoto, et al. Demonstration of an optical dentin hardness measuring device using bovine dentin with different demineralization times. Journal of Biomedical Optics. 2022. 27. 10. 105004-1-105004-13
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MISC (116):
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Patents (20):
  • 光う蝕診断計及び光う蝕診断方法、並びにう蝕診断システム
  • 光う蝕診断計及び光う蝕診断方法
  • 光う蝕診断計及び光う蝕診断方法
  • 光象牙質診断装置及び光象牙質診断方法
  • 光線力学的治療装置及びその作動方法
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Lectures and oral presentations  (12):
  • Computational evaluation of the effect of interstitial PDT with 5-ALA for pretreatment planning (Conference Presentation)
    (17th International Photodynamic Association World Congress 2019)
  • Evaluation of a novel photosensitizing drug having antitumor effect for advanced prostate cancer
    (Optics InfoBase Conference Papers 2017)
  • Hemagglutinating virus of Japan envelope (HVJ-E) allows targeted and efficient delivery of photosensitizer for photodynamic therapy against advanced prostate cancer
    (Optical Molecular Probes, Imaging and Drug Delivery, OMP 2015 2015)
  • Optical properties of tumor tissues grown on the chorioallantoic membrane of chicken eggs measured with a double integrating sphere and inverse monte carlo method
    (Optics InfoBase Conference Papers 2013)
  • Development of selective laser treatment techniques using mid-infrared tunable nanosecond pulsed laser
    (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 2010)
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Education (3):
  • 1998 - 2001 Tokyo University of Science
  • 1996 - 1998 Tokyo University of Science
  • 1992 - 1996 Shizuoka University Faculty of Engineering
Work history (8):
  • 2020/04 - 現在 Osaka University Associate Professor
  • 2015/04 - 2020/03 Osaka University Associate Professor
  • 2014/04 - 2015/03 Osaka University Associate Professor
  • 2009/06 - 2014/03 Osaka University Graduate School of Engineering Continuing Professional Development Center Assistant Professor
  • 2006/06 - 2009/05 Osaka University
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Awards (18):
  • 2020/06 - International Phototherapy Association Best Paper Award 2019 of Laser Therapy Photodynamic therapy by lysosomal-targeted drug delivery using talaporfin sodium incorporated into inactivated virus particles
  • 2019/10 - 日本レーザー歯学会 日本レーザー歯学会優秀発表賞 ヒト口腔扁平上皮癌由来細胞に対する5-アミノレブリン酸を用いたPDDの検討
  • 2018/05 - 日本質量分析学会・日本プロテオーム学会 日本質量分析学会・日本プロテオーム学会2018年合同大会ベストプレゼンテーション賞優秀賞 大気圧連続流赤外レーザーエレクトロスプレーイオン化法を用いた緩衝液または塩を含んだペプチド試料の測定およびESI法との比較
  • 2018/02 - Michael T. Eismann, Editor-in-Chief of Optical Engineering Appreciation for serving as a reviewer awarded to Hisanao Hazama for Optical Engineering during the calendar year of 2017 Presented by Michael T. Eismann, Editor-in-Chief
  • 2018/02 - International Phototherapy Association Prof. Ming Chien Kao Award 2017 of Laser Therapy Evaluation of endovenous laser ablation for varicose veins using a computer simulation model (Secondary publication)
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Association Membership(s) (10):
日本歯科用レーザー・ライト学会 ,  日本レーザー治療学会 ,  日本光線力学学会 ,  日本レーザー医学会 ,  American Society for Mass Spectrometry ,  日本レーザー歯学会 ,  日本質量分析学会 ,  レーザー学会 ,  電気学会 ,  応用物理学会
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