J-GLOBAL ID:201901007014032720   Update date: Jun. 12, 2024

Hazama Hisanao

ハザマ ヒサナオ | Hazama Hisanao
Affiliation and department:
Research field  (5): Analytical chemistry ,  Chemical biology ,  Biomedical engineering ,  Medical systems ,  Tumor diagnostics and therapeutics
Research keywords  (8): Mass spectrometry imaging ,  Laser ionization mass spectrometry ,  Optical measurement of tooth hardness ,  Photodynamic diagnosis and therapy ,  Healthy life expectancy ,  Opto-biomechanics ,  Tissue optics ,  Laser
Research theme for competitive and other funds  (11):
  • 2021 - 2024 Development of single-cell mass spectrometry imaging techniques to analyze drug-cell interactions
  • 2020 - 2023 有機溶存物質のエアロミセル化・水マトリックス支援ソフトイオン化による直接質量分析
  • 2020 - 2023 レーザーESD標準化に向けた消化器癌の超早期検出とその場適応診断法の確立
  • 2019 - 2021 Development of Computational Clinical Trial Mehtod for Laser Medicine
  • 2016 - 2019 Development of infrared laser ionization techniques for high throughput mass spectrometry of membrane proteins
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Papers (141):
  • Sota Kondo, Yutaka Tomioka, Naohiro Fujimoto, Atsushi Mine, Satoshi Yamaguchi, Saeko Okumura, Hiroaki Tanimoto, Kenzo Yasuo, Kazushi Yoshikawa, Kazuyo Yamamoto, et al. Mechanism of dentin hardness measurements using a dentin hardness measuring device with a light-emitting diode. Journal of Biomedical Optics. 2024. 29. 02. 025002-1-025002-14
  • Sochi J. Ogbonna, William Y. York, Takahiro Nishimura, Hisanao Hazama, Hideo Fukuhara, Keiji Inoue, Kunio Awazu. Increased fluorescence observation intensity during the photodynamic diagnosis of deeply located tumors by fluorescence photoswitching of protoporphyrin IX. Journal of Biomedical Optics. 2023. 28. 5. 1-15
  • Sota Kondo, Hisanao Hazama, Yutaka Tomioka, Atsushi Mine, Satoshi Yamaguchi, Saeko Okumura, Hiroaki Tanimoto, Kenzo Yasuo, Kazushi Yoshikawa, Kazuyo Yamamoto, et al. Demonstration of an optical dentin hardness measuring device using bovine dentin with different demineralization times. Journal of Biomedical Optics. 2022. 27. 10. 105004-1-105004-13
  • Aya Kasakawa, Shinichi Sekine, Kenji Tanaka, Jumpei Murakami, Sota Kondo, Hisanao Hazama, Kunio Awazu, Shigehisa Akiyama. Effect of Q-switched Er:YAG laser irradiation on bonding performance to dentin surface. Dental Materials Journal. 2022. 41. 4. 616-623
  • Hiroki Kannen, Yuto Miyoshi, Hisanao Hazama, Kunio Awazu. Improvement in Ionization Efficiency Using Metal Oxide Nanoparticles in Laser Desorption/Ionization Mass Spectrometry of a Cancer Drug. Mass Spectrometry. 2021. 10. 1. A0099-1-A0099-5
MISC (117):
Lectures and oral presentations  (12):
  • Computational evaluation of the effect of interstitial PDT with 5-ALA for pretreatment planning (Conference Presentation)
    (17th International Photodynamic Association World Congress 2019)
  • Evaluation of a novel photosensitizing drug having antitumor effect for advanced prostate cancer
    (Optics InfoBase Conference Papers 2017)
  • Hemagglutinating virus of Japan envelope (HVJ-E) allows targeted and efficient delivery of photosensitizer for photodynamic therapy against advanced prostate cancer
    (Optical Molecular Probes, Imaging and Drug Delivery, OMP 2015 2015)
  • Optical properties of tumor tissues grown on the chorioallantoic membrane of chicken eggs measured with a double integrating sphere and inverse monte carlo method
    (Optics InfoBase Conference Papers 2013)
  • Development of selective laser treatment techniques using mid-infrared tunable nanosecond pulsed laser
    (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 2010)
Education (3):
  • 1998 - 2001 Tokyo University of Science
  • 1996 - 1998 Tokyo University of Science
  • 1992 - 1996 Shizuoka University Faculty of Engineering
Work history (8):
  • 2020/04 - 現在 Osaka University Associate Professor
  • 2015/04 - 2020/03 Osaka University Associate Professor
  • 2014/04 - 2015/03 Osaka University Associate Professor
  • 2009/06 - 2014/03 Osaka University Graduate School of Engineering Continuing Professional Development Center Assistant Professor
  • 2006/06 - 2009/05 Osaka University
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Association Membership(s) (10):
日本歯科用レーザー・ライト学会 ,  日本レーザー治療学会 ,  日本光線力学学会 ,  日本レーザー医学会 ,  American Society for Mass Spectrometry ,  日本レーザー歯学会 ,  日本質量分析学会 ,  レーザー学会 ,  電気学会 ,  応用物理学会
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