Rchr
J-GLOBAL ID：201901007500103957   Update date: Nov. 21, 2024

Christoph Gerle

ゲーレ クリストフ | Christoph Gerle
Affiliation and department：
RIKEN SPring-8 Center

About RIKEN SPring-8 Center


Job title： Research Scientist
Homepage URL  (1)： https://www.riken.jp/en/research/labs/rsc/adv_photon/life_sci_res_infrastruct/index.html
Research field  (2)： Biophysics ,  Structural biochemistry
Research keywords  (8)： single particle analysis ,  structural biology ,  ATP synthase ,  membrane biology ,  biophysics ,  bioenergetics ,  membrane protein ,  cryo electron microscopy
Research theme for competitive and other funds  (4)：
  • 多様な顕微鏡技術による膜タンパク質複合体の多階層での機能構造研究
  • クライオ電子顕微鏡のフィードバックに基づく膜タンパク質複合体の生産と技術支援
  • 極低温単粒子時分割解析によるFoF1-ATP合成酵素のFo/F1共役機構の研究
  • 極低温単粒子解析による哺乳動物のF-ATP合成酵素の原子レベルの構造機能研究
Papers (38)：
  • Kazuhiro Abe, Jeff McDermott, Hridya Valia Madapally, Parthiban Marimuthu, Chai C. Gopalasingam, Christoph Gerle, Hideki Shigematsu, Himanshu Khandelia, Gustavo Blanco. Molecular Structure of the Na+,K+-ATPase α4β1 Isoform in Its Ouabain-Bound Conformation. International Journal of Molecular Sciences. 2024. 25. 22. 12397-12397
  • Gabriele Coluccino, Alessandro Negro, Antonio Filippi, Camilla Bean, Valentina Pia Muraca, Clarissa Gissi, Diana Canetti, Maria Chiara Mimmi, Elisa Zamprogno, Francesco Ciscato, et al. N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase. Communications Biology. 2024. 7. 1. 1-15
  • Christoph Gerle, Chimari Jiko, Atsuki Nakano, Ken Yokoyama, Chai C. Gopalasingam, Hideki Shigematsu, Kazuhiro Abe. Human F-ATP synthase as a drug target. Pharmacological Research. 2024. 209. 1-13
  • Ginga Shimakawa, Manon Demulder, Serena Flori, Akihiro Kawamoto, Yoshinori Tsuji, Hermanus Nawaly, Atsuko Tanaka, Rei Tohda, Tadayoshi Ota, Hiroaki Matsui, et al. Diatom pyrenoids are encased in a protein shell that enables efficient CO2 fixation. Cell. 2024
  • Chimari Jiko, Jiannan Li, Youngsun Moon, Yoshito Tanaka, Chai C Gopalasingam, Hideki Shigematsu, Pil Seok Chae, Genji Kurisu, Christoph Gerle. NDT-C11 as a viable novel detergent for single particle cryo-EM. ChemPlusChem. 2024. e202400242
ｍore...
MISC (10)：
  • 慈幸千真理, 三角裕子, 栗栖源嗣, 森本幸生, 月原冨武, GERLE Christoph. Preparation of mammalian mitochondrial FoF1ATP synthase for high-resolution structural analysis. 日本生体エネルギー研究会討論会講演要旨集. 2023. 49th
  • Hideki SHIGEMATSU, Christoph GERLE. Public Use CryoTEM at SPring-8. Nihon Kessho Gakkaishi. 2021. 63. 4. 262-266
  • Gerle, Christoph. The Value of Diversity. Seibutsu Butsuri. 2021. 61. 1. 046-048
  • 福澤大喜, 東田怜, NAWALY Hermanus, 森嶋菜摘, 大久保亮佑, 田中秀明, 川本晃大, GERLE Christoph, 松井啓晃, 松田祐介, et al. 珪藻Thalassiosira pseudonana由来ルビスコのX線結晶構造解析. 日本結晶学会年会講演要旨集. 2021. 2021
  • Gerle, Christoph. Corona, cryo-EM and Japan. Asahi Ronza. 2020
ｍore...
Books (1)：
  • The Nuclear Dream: The Hidden World of Atomic Energy
    DOM Publishers 2020
Lectures and oral presentations  (31)：
  • Structure of an antiparallel ATP synthase dimer: implications for mitochondrial energy conversion
    (The 97th annual meeting of the Japanese Biochemical Society 2024)
  • Surprise, surprise - ATP synthase as the PTP
    (Frontiers in Mitochondrial Research, University of Padova, Italy 2024)
  • A planar dimer of bovine F-ATP synthase
    (OsakaMitoMeeting2024 2024)
  • Challenges and solutions for in vitro experiments with mammalian F-ATP synthase
    (Cold Spring Harbor Asia Meetings - Mitochondria and Metabolism in Health and Disease 2023)
  • Cryo-EM structure of a functional monomeric Photosystem I from Thermosynechococcus elongatus reveals 'red' chlorophyll cluster
    (GTR Seminar - Topics in Advanced Biological Science 2021)
ｍore...
Education (5)：
  • 2003 - 2006 Kyoto University Faculty of Science Department of Biophysics
  • 2000 - 2002 (Beijing Normal University, China Chinese Studies)
  • 2000 - 2000 Imperial College London, U.K. Master Thesis Research
  • 1993 - 2000 Leibnitz University Hannover/Hannover Medical School, Germany
  • 1997 - 1998 (Nanjing University, China Chinese Studies)
Professional career (1)：
  • Ph.D. (Kyoto University)
Work history (9)：
  • 2021/04 - 現在 Life Science Research Infrastructure Group Advanced Photon Technology Division RIKEN SPring-8 Center (RSC) RIKEN Research Scientist
  • 2021/04 - 2023/03 Institute for Protein Research, Osaka University Visiting Associate Professor
  • 2017/04 - 2021/03 Osaka University Institute for Protein Research, Laboratory of Protein Crystallography Specially Appointed Associate Professor
  • 2019/04 - 2020/03 Kyoto University Institute for Integrated Radiation and Nuclear Science Visiting Professor
  • 2017/07 - 2017/08 University of Padova Graduate School of Biomedical Sciences Visiting Scientist
Show all
Awards (2)：
  • 2019/09 - Delft University of Technology, Department of Biotechnology Kluyver Colloquium
  • 2015 - Paper Award of the Japanese Society of Microscopy
Association Membership(s) (2)：
PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE BIOPHYSICAL SOCIETY OF JAPAN
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