Furuhama Ayako

フルハマアヤコ | Furuhama Ayako

Affiliation and department：

Research field (4)： Biological, health, and medical informatics , Environmental load/risk assessment , Environmental effects of chemicals , Environmental impact assessment

Research theme for competitive and other funds (2)：

2017 - 2021 DEVELOPMENT OF CHRONIC FISH TOXICITY MODELS BASED ON AN INTERSPECIES RELATIONSHIP AND MOLECULAR DESCRIPTORS
2004 - 2006 分子軌道計算のための高精度溶媒効果理論の開発と応用

Papers (28)：

Ayako Furuhama, Kei-ichi Sugiyama, Masamitsu Honma. Ames mutagenicity of 15 aryl, benzyl, and aliphatic ring N-nitrosamines. Regulatory Toxicology and Pharmacology. 2025
Shigeharu Muto, Ayako Furuhama, Mika Yamamoto, Yasuteru Otagiri, Naoki Koyama, Seiji Hitaoka, Yusuke Nagato, Hirofumi Ouchi, Masahiro Ogawa, Kisako Shikano, et al. Local QSAR based on quantum chemistry calculations for the stability of nitrenium ions to reduce false positive outcomes from standard QSAR systems for the mutagenicity of primary aromatic amines. Genes and Environment. 2024
A. Furuhama, A. Kitazawa, J. Yao, C.E. Matos dos Santos, J. Rathman, C. Yang, J.V. Ribeiro, K. Cross, G. Myatt, G. Raitano, et al. Evaluation of QSAR models for predicting mutagenicity: outcome of the Second Ames/QSAR international challenge project. SAR and QSAR in Environmental Research. 2023. 34. 12. 983-1001
Takehiko I Hayashi, Ayako Furuhama, Hiroyuki Yokomizo, Hiroshi Yamamoto. Quantitative analyses of misclassification rates in the hazard classification of environmental chemicals: Evaluation of procedures for deriving predicted no-effect concentrations in the Chemical Substance Control Law in Japan. Risk analysis : an official publication of the Society for Risk Analysis. 2022
P.I. Petkov, H. Ivanova, M. Honma, T. Yamada, T. Morita, A. Furuhama, S. Kotov, E. Kaloyanova, G. Dimitrova, O. Mekenyan. Differences between in vitro and in vivo genotoxicity due to metabolism: The role of kinetics. Computational Toxicology. 2022. 22. 100222-100222

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MISC (6)：

Shraddha Thakkar, William Slikker, Frank Yiannas, Primal Silva, Burton Blais, Kern Rei Chng, Zhichao Liu, Alok Adholeya, Francesco Pappalardo, Mônica da Luz Carvalho Soares, et al. Artificial intelligence and real-world data for drug and food safety - A regulatory science perspective. Regulatory Toxicology and Pharmacology. 2023. 140. 105388-105388
Ayako Furuhama, Toshio Kasamatsu, Kei-ichi Sugiyama, Masamitsu Honma. Curation of more than 10,000 Ames test data used in the Ames/QSAR International Challenge Projects. QSAR in Safety Evaluation and Risk Assessment. 2023. 365-372
Ayako Furuhama. Combination of Read-Across and QSAR for Ecotoxicity Prediction: A Case Study of Green Algae Growth Inhibition Toxicity Data. Methods in Pharmacology and Toxicology. 2020. 591-613
FURUHAMA Ayako, IMAMURA Takashi, MAEDA Satoshi, TAKETSUGU Tetsuya. Systematic exploration of reaction pathways between CH3NH2 and OH. 化学反応討論会講演要旨集. 2013. 29th. 91
古濱彩子, 白石寛明. 化学物質の生態毒性予測システムKATEとQSAR. 日本化学会情報化学部会誌. 2012. 30. 3. 42-42

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Education (1)：

2001 - 2004 Nagoya University Graduate School of Human Informatics

Work history (6)：

2020/02 - 現在 National Institute of Health Sciences Center for Biological Safety and Research, Division of Genetics and Mutagenesis, Senior staff scientist
2016/04 - 2020/01 National Institute for Environmental Studies (NIES) Center for Health and Environmental Risk Research Senior Researcher
2013/04 - 2016/03 National Institute for Environmental Studies (NIES) Center for Environmental Risk Research Senior Researcher
2008/04 - 2013/03 National Institute for Environmental Studies (NIES) Research Center for Environmental Risk NIES Special Researcher/Researcher
2007/04 - 2008/03 Imperial College London, UK JSPS Postdoctoral Fellow for Research Abroad

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Association Membership(s) (4)：

The Pharmaceutical Society of Japan , The Japanese Society of Toxicology , The Division of Structure-Activity Studies, The Pharmaceutical Society of Japan , The Japanese Environmental Mutagen Society

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