Takai Yoshiki

タカイヨシキ | Takai Yoshiki

Research field (1)： Neurology

Research theme for competitive and other funds (4)：

2021 - 2024 MOG抗体関連疾患の臨床表現型と重症化に関する分子免疫病理学的解析
2017 - 2020 Involvement of ischemic tissue injury in inflammatory demyelinating disease and its therapeutic application
2016 - 2019 Development of new therapy for neuromyelitis optica using its animal models and anti-AQP4 antibodies.
2015 - 2017 Elucidation of demyelination mechanism caused by astrocyte injury

Papers (126)：

Kimihiko Kaneko, Hiroshi Kuroda, Yuki Matsumoto, Naohiro Sakamoto, Naoya Yamazaki, Naoki Yamamoto, Shu Umezawa, Chihiro Namatame, Hirohiko Ono, Yoshiki Takai, et al. Different Complement Activation Patterns Following C5 Cleavage in MOGAD and AQP4-IgG+NMOSD. Neurology(R) neuroimmunology & neuroinflammation. 2024. 11. 5. e200293
Chihiro Namatame, Yoichiro Abe, Yoshiki Miyasaka, Yoshiki Takai, Yuki Matsumoto, Toshiyuki Takahashi, Tomoji Mashimo, Tatsuro Misu, Kazuo Fujihara, Masato Yasui, et al. Humanized-Aquaporin-4-Expressing Rat Created by Gene-Editing Technology and Its Use to Clarify the Pathology of Neuromyelitis Optica Spectrum Disorder. International journal of molecular sciences. 2024. 25. 15
Yuki Matsumoto, Kunio Tarasawa, Tatsuro Misu, Chihiro Namatame, Yoshiki Takai, Hiroshi Kuroda, Kazuo Fujihara, Kiyohide Fushimi, Kenji Fujimori, Masashi Aoki. Dynamic changes in patient admission and their disabilities in multiple sclerosis and neuromyelitis optica: A Japanese nationwide administrative data study. Multiple Sclerosis and Related Disorders. 2024. 81. 105349-105349
Tatsuro Misu, Yuki Matsumoto, Kimihiko Kaneko, Toshiyuki Takahashi, Yoshiki Takai, Hirohiko Ono, Chihiro Namatame, Shuhei Nishiyama, Juichi Fujimori, Hiroshi Kuroda, et al. Myelin oligodendrocyte glycoprotein antibody-associated disorders: An overview. Clinical and Experimental Neuroimmunology. 2023
金子仁彦, 黒田宙, 小野紘彦, 松本勇貴, 阪本直広, 山崎直也, 山本尚輝, 梅澤周, 生田目知尋, 高井良樹, et al. MOGAD急性期髄液における活性化補体の解析. 神経免疫学. 2023. 28. 1. 200-200

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MISC (93)：

金子仁彦, 黒田宙, 黒田宙, 小野紘彦, 松本勇貴, 松本勇貴, 松本勇貴, 山崎直也, 山本尚輝, 梅澤周, et al. Analysis of CSF complement profile in myelin oligodendrocyte glycoprotein associated disease. 補体. 2023. 60. 1
大野尭之, 井泉瑠美子, 鈴木直輝, 高井良樹, 小野理佐子, 黒田宙, 割田仁, 竪山真規, 川崎永美子, 鈴木靖士, et al. 高度の嚥下障害と認知機能低下を認めた若年発症眼咽頭型筋ジストロフィーの1例. 臨床神経学. 2022. 62. 5. 409-409
金子仁彦, 浪岡靖弘, 大山綾音, 高井良樹, 檜森紀子, 中澤徹, 三須建郎, 青木正志. Cases of anti-aquaporin4 antibody-positive neuromyelitis optica spectrum disorder treated with eculizumab initiated immediately after acute treatment. 神経治療学(Web). 2022. 39. 4
金子仁彦, 松本勇貴, 藤盛寿一, 生田目千尋, 高井良樹, 中島一郎, 三須建郎, 青木正志. SARS-CoV-2ワクチン後免疫性神経疾患の臨床的特徴と予後. Neuroinfection (Web). 2022. 27. 2
藤原一男, 松本勇貴, 三須建郎, 麦倉俊司, 高井良樹, 西山修平, 黒田宙, 高橋利幸, 藤盛寿一, 中島一郎, et al. 神経免疫疾患のエビデンスに基づく診断基準・重症度分類・ガイドラインの妥当性と患者QOLの検証抗MOG抗体関連疾患と抗AQP4陽性視神経脊髄炎の頭部MRI画像における病変分布の比較検討. 神経免疫疾患のエビデンスに基づく診断基準・重症度分類・ガイドラインの妥当性と患者QOLの検証令和2年度総括・分担研究報告書(Web). 2021

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