Osaka University
Department of Cancer Genome Informatics, Graduate School of Medicine
Research field (4):
Genomics
, Systems genomics
, Genetics
, Evolutionary biology
Research theme for competitive and other funds (4):
2021 - 2024 ゲノム進化およびがんクローン進化における量感受性遺伝子のコピー数進化解析
日本人集団におけるがん腫横断的な全ゲノム解析
希少がん、難治がんである十二指腸乳頭部癌の多層オミックス解析と微小環境理解に基づく治療標的の研究
進化遺伝学的アプローチとマルチオミックス情報解析による膵臓神経内分泌腫瘍のゲノム進化に関する研究
Papers (26):
Shoko Ikuta, Yutaka Saito, So Takata, Yoichiro Nakatani, Izumi Nagatomo, Satoshi Shiba, Yoshito Takeda, Yasushi Totoki, Sayaka Mizutani, Hironori Sunakawa, et al. Variability in non-tumor areas of colorectal cancer patients as revealed by endoscopic intestinal step biopsies. Molecular cancer. 2024. 23. 1. 249-249
Tamara Cubiella, Lucía Celada, Jaime San-Juan-Guardado, Raúl Rodríguez-Aguilar, Álvaro Suárez-Priede, María Poch, Francisco Dominguez, Iván Fernández-Vega, Pedro Montero-Pavón, Mario F Fraga, et al. PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas. The Journal of pathology. 2024
Masafumi Horie, Hidenori Tanaka, Masami Suzuki, Yoshihiko Sato, So Takata, Erina Takai, Naoya Miyashita, Akira Saito, Yoichiro Nakatani, Shinichi Yachida. An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinoma. Cancer science. 2023. 114. 6. 2596-2608
Shinichi Yachida, Yasushi Totoki, Michael Noe, Yoichiro Nakatani, Masafumi Horie, Kenta Kawasaki, Hiromi Nakamura, Mihoko Saito-Adachi, Masami Suzuki, Erina Takai, et al. Comprehensive Genomic Profiling of Neuroendocrine Carcinomas of the Gastrointestinal System. Cancer discovery. 2021. 12. 3. 692-711
Yoichiro Nakatani, Prashant Shingate, Vydianathan Ravi, Nisha E. Pillai, Aravind Prasad, Aoife McLysaght, Byrappa Venkatesh. Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution. Nature Communications. 2021. 12. 1