Rchr
J-GLOBAL ID:201901008999541263   Update date: May. 07, 2026

Michiko Horiguchi

ホリグチ ミチコ | Michiko Horiguchi
Affiliation and department:
Research field  (4): Pharmaceuticals - chemistry and drug development ,  Biomedical engineering ,  Polymer materials ,  Pharmaceuticals - analytical and physicochemistry
Research keywords  (10): 創薬化学 ,  物理化学 ,  物理薬学 ,  細胞製剤設計学 ,  生体医工学 ,  ドラッグデリバリー ,  時間治療 ,  再生治療 ,  幹細胞 ,  がん
Research theme for competitive and other funds  (16):
  • 2023 - 2026 腎所属リンパ節を標的とするAKI-to-CKD transitionの新規治療戦略の構築
  • 2024 - 2026 次世代クッション型の細胞凍結保護剤の開発
  • 2022 - 2025 Safety Evaluation of Proline Hydroxylase Inhibitors Focusing on Renal Cell Carcinoma with Genetic Mutation
  • 2020 - 2024 幹細胞バンクの構築に向けた革新的な幹細胞製剤化技術の開発
  • 2019 - 2021 Regenerative therapy using stem cell sphere drug delivery system
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Papers (54):
  • Moka Ikeda, Yuya Tsurudome, Mai Enrin, Yukiyo Wada, Michiko Horiguchi, Kentaro Ushijima. German Chamomile (Matricaria chamomilla) Induces Cytochrome P450 Expression Through Increased BMAL1 Protein Expression in Liver Nuclei. Biochemical genetics. 2025
  • Yukiyo Wada, Masaki Inoko, Kanako Ishihara, Karin Fukumoto, Yuya Tsurudome, Michiko Horiguchi, Akio Fujimura, Kentaro Ushijima. Aging Reduces ATP-Binding Cassette Transporter Expression in Brain Microvessels of Mice. Pharmaceuticals. 2025. 18. 2. 191-191
  • Michiko Horiguchi, Kenichi Yoshihara, Yoichi Mizukami, Kenji Watanabe, Yuya Tsurudome, Kentaro Ushijima. The Diurnal Variation in Mitochondrial Gene in Human Type 2 Diabetic Mesenchymal Stem Cell Grafts. International journal of molecular sciences. 2025. 26. 2
  • Michiko Horiguchi, Kenichi Yoshihara, Kenji Watanabe, Yuya Tsurudome, Yoichi Mizukami, Kentaro Ushijima. Circadian Rhythms of Clock Genes After Transplantation of Mesenchymal Stem Cells with Type 2 Diabetes Mellitus. International Journal of Molecular Sciences. 2024. 25. 23. 13145-13145
  • Yuya Tsurudome, Yumi Takahata, Nao Morita, Soma Yamauchi, Takuya Iyoda, Michiko Horiguchi, Kentaro Ushijima. Increased SPARC in brain microvessels of ob/ob mice accelerates molecular transport into the brain accompany with albumin. Life sciences. 2024. 122990-122990
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MISC (79):
  • 別府航多, 鶴留優也, 秋山滋男, 堀口道子, 牛島健太郎. Pharmaceutical comparison study of tafluprost ophthalmic solution between generic and brand-name products. 山陽小野田市立山口東京理科大学紀要. 2025. 8
  • 水野智博, 中西正範, 堀口道子, 江口博晶, 中井剛, 山田成樹, 坪井直毅. Impact of high-dose hypoxia-inducible factor-prolyl hydroxylase inhibitor on the growth of renal cell carcinoma. 日本薬学会年会要旨集(Web). 2025. 145th
  • 和田由喜世, 猪子真輝, 石原加奈子, 福元果麟, 鶴留優也, 堀口道子, 堀口道子, 藤村昭夫, 藤村昭夫, 牛島健太郎, et al. Changes of ABC transporter expression by aging in blood-brain barrier of mouse. 日本薬学会年会要旨集(Web). 2025. 145th
  • 山内荘摩, 鶴留優也, 熊野那奈, 伊藤貴仁, 伊藤貴仁, 出水庸介, 出水庸介, 白石廉太朗, 堀口道子, 堀口道子, et al. Species differences in albumin binding of statins. 日本薬学会年会要旨集(Web). 2025. 145th
  • 諸田 智也, 小西 紗椋, 吉原 謙一, 松本 拓真, 鶴留 優也, 牛島 健太郎, 秦 慎一, 堀口 道子. ナノ粒子保護剤を用いた幹細胞の凍結乾燥製剤の開発と評価. 2024
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Patents (7):
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Education (1):
  • 2009 - 2012 Kyushu University Graduate School of Pharmaceutical Sciences
Professional career (1):
  • 博士(薬学) (九州大学)
Work history (6):
  • 2025/04 - 現在 Okayama University Professor
  • 2024/04 - 2025/03 山口東京理科大学 工学部 医薬工学科 准教授
  • 2024/04 - 2025/03 Sanyo Onoda City University Faculty of Pharmaceutical Sciences
  • 2019/04 - 2024/03 Tokyo University of Science,Yamaguchi
  • 2016/04 - 2019/03 Columbia University in the City of New York
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Awards (11):
  • 2020/12 - 第41回 日本臨床薬理学会学術集会 優秀演題賞
  • 2018/07 - SHARE Cancer Support 2nd SHARE Study Workshop Certicate of Appreciation
  • 2017/04 - JMSA New York Life Science Forum 2017 JMSA Award 2017
  • 2015/05 - 第30回 日本薬剤学会年会 優秀発表賞
  • 2014/08 - 3rd Postgraduate Conference on Pharmaceutical Science 3rd iPoPs Certicate of Appreciation
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