Hirofumi Toda

トダヒロフミ | Hirofumi Toda

Affiliation and department：
Homepage URL (1)： https://wpi-iiis.tsukuba.ac.jp/japanese/research/member/detail/%e6%88%b8%e7%94%b0-%e6%b5%a9%e5%8f%b2/

Research field (1)： Neuroscience - general

Research keywords (4)： biochemistry , molecular biology , genetics , Sleep

Research theme for competitive and other funds (8)：

2024 - 2028 ストレス誘因性睡眠の作用機序の解明
2023 - 2026 Establishment of a research base to study the extreme cold tolerance using Drosophila melanogaster as a model system
2022 - 2026 Immunity and sleep: two distinct biological phenomena controlled by liquid-liquid
2022 - 2025 'sleep' regulation via LLPS
2021 - 2024 Chrono-proteinology: principle and design for protein timers

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Papers (11)：

Saaya Hario, Giang N T Le, Hikaru Sugimoto, Kei Takahashi-Yamashiro, Suguru Nishinami, Hirofumi Toda, Selene Li, Jonathan S Marvin, Shinya Kuroda, Mikhail Drobizhev, et al. High-Performance Genetically Encoded Green Fluorescent Biosensors for Intracellular l-Lactate. ACS central science. 2024. 10. 2. 402-416
Yusuke Nasu, Abhi Aggarwal, Giang N T Le, Camilla Trang Vo, Yuki Kambe, Xinxing Wang, Felix R M Beinlich, Ashley Bomin Lee, Tina R Ram, Fangying Wang, et al. Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging. Nature communications. 2023. 14. 1. 6598-6598
Joseph L Bedont, Hirofumi Toda, Mi Shi, Christine H Park, Christine Quake, Carly Stein, Anna Kolesnik, Amita Sehgal. Short and long sleeping mutants reveal links between sleep and macroautophagy. eLife. 2021. 10
Risa Yamazaki, Hirofumi Toda, Paul-Antoine Libourel, Yu Hayashi, Kaspar E Vogt, Takeshi Sakurai. Evolutionary Origin of Distinct NREM and REM Sleep. Frontiers in psychology. 2020. 11. 567618-567618
Hirofumi Toda, Julie A Williams, Michael Gulledge, Amita Sehgal. A sleep-inducing gene, nemuri, links sleep and immune function in Drosophila. Science (New York, N.Y.). 2019. 363. 6426. 509-515

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MISC (5)：

Hiroaki Machizuki, Hirofumi Toda, Toshifumi Tomoda, Katsuo Furukubo-Tokunaga. UNC-51 regulates axon/dendrite patterning and polarized protein trafficking in Drosophila. NEUROSCIENCE RESEARCH. 2008. 61. S160-S160
Y. Maruyama, T. Ando, K. Honjo, M. Shimoda, H. Mochizuki, H. Toda, A. Kamiya, N. Ishida, T. Tomoda, A. Sawa, et al. Overexpression of DISC1 impairs associative learning and arousal in Drosophila. NEUROSCIENCE RESEARCH. 2007. 58. S123-S123
Hiroaki Mochizuki, Hirofumi Toda, Toshifumi Tomoda, Katsuo Furukubo-Tokunaga. UNC-51 regulates axonal and dendritic patterning in the Drosophila brain. NEUROSCIENCE RESEARCH. 2007. 58. S87-S87
Tetsuya Ando, Yuya Kawanaka, Minoru Saito, Hiroaki Mochizuki, Ken Honjo, Hirofumi Toda, Toshifumi Tomoda, Akira Sawa, Katsuo Furukubo-Tokunaga. Overexpression of disrupted-in-Schizophrenia-1 [DISC1] impairs associative learning in Drosophila. NEUROSCIENCE RESEARCH. 2006. 55. S255-S255
Hiroaki Mochizuki, Hirofumi Toda, Emiko Suzuki, Joseph Gindhart, Toshifumi Tomoda, Katsuo Furukubo-Tokunaga. The conserved Ser/Thr kinase UNC51 functions with UNC-76 to regulate axonal transport in Drosophila. NEUROSCIENCE RESEARCH. 2006. 55. S216-S216

Lectures and oral presentations (11)：

ストレスによって誘因される睡眠の分子・神経メカニズム ~新規睡眠誘引因子’Nemuri’の作用機序の解明~
(内分泌・代謝学共同利用共同研究拠点セミナー 2023)
ストレスによって誘因される睡眠の分子・神経メカニズム ~新規睡眠誘引因子’Nemuri’の作用機序の解明~
(ExCELLSセミナー 2023)
「時間タンパク質学」: 睡眠誘引因子Nemuriの複合体の理解
(医学研シンポジウム 2023)
ストレスによって誘因される睡眠の分子メカニズム ~新規睡眠誘引因子“Nemuri” の作用機序の解明~
(蛋白質学会 2023)
睡眠誘因因子「Nemuri」の物性の理解へ向けて
(生化学会 2022)

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Education (2)：

Professional career (1)：

Work history (4)：

Awards (2)：

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