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J-GLOBAL ID：201901009719764870   Update date: Mar. 31, 2024

Masai Ichiro

マサイ イチロウ | Masai Ichiro
Affiliation and department：
Okinawa Institute of Science and Technology Graduate University Developmental Neurobiology Unit

About Okinawa Institute of Science and Technology Graduate University Developmental Neurobiology Unit


Job title： Professor
Homepage URL  (2)： https://groups.oist.jp/ja/dnu ,  https://groups.oist.jp/dnu
Research field  (4)： Neuroscience - general ,  Genetics ,  Cell biology ,  Developmental biology
Research keywords  (8)： neuronal regeneration ,  microglia ,  photoreceptor degeneration ,  apoptosis ,  cell death ,  cell differentiation ,  lens ,  retina
Research theme for competitive and other funds  (6)：
  • 2014 - 2017 ER-resident BH3-only protein, BNip1, induces apoptosis in response to excessive activation of vesicular transport in zebrafish photoreceptors
  • 2011 - 2015 Establishment of a basis to study vertebrate phoneme based on transposon-mediated genetic methods
  • 2011 - 2012 Mechanism underlying photoreceptor degeneration in response to vesicular fusion defects
  • 2006 - 2008 Mechanism underlying retinal lamination in zebrafish
  • 1999 - 2000 Functional analysis of zebrafish retina-specific atonal gene and its expression profile
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Papers (52)：
  • Swathy Babu, Yuki Takeuchi, Ichiro Masai. Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina. eLife. 2022. 11
  • Manana Kutsia, Yuki Takeuchi, Nishtha Ranawat, Ichiro Masai. Single-cell transcriptome analysis reveals heterogeneity and a dynamic regenerative response of quiescent radial glia in adult zebrafish brain. BioRxiv. 2022
  • Mai Ahmed, Yutaka Kojima, Ichiro Masai. Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation. eLife. 2022. 11
  • Nishtha Ranawat, Ichiro Masai. Mechanisms underlying microglial colonization of developing neural retina in zebrafish. eLife. 2021. 10
  • Yuko Nishiwaki, Ichiro Masai. β-SNAP activity in the outer segment growth period is critical for preventing BNip1-dependent apoptosis in zebrafish photoreceptors. Scientific reports. 2020. 10. 1. 17379-17379
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MISC (27)：
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Lectures and oral presentations  (76)：
  • cGMP metabolismの異常を介した視細胞変性メカニズム
    (日本生化学会大会(Web) 2017)
  • 小胞体上のBH3オンリータンパクであるBNip1は小胞輸送の過剰な活性化により細胞死を誘導する
    (日本生化学会大会(Web) 2017)
  • VPS45 mutation induces ectopic lens fiber differentiation in the lens epithelium through the activation of TGF-beta signaling
    (XXII Biennial Meeting of the International Society for Eye Research (ISER) 2016)
  • ゼブラフィッシュの系統管理と遺伝学研究への活用
    (日本実験動物学会総会講演要旨集 2015)
  • 正中線交叉における交連軸索のSlit応答性スイッチの分子基盤:Robo1細胞内輸送系とArf6シグナリングの役割
    (日本生化学会大会(Web) 2015)
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Education (2)：
  • 1988 - 1992 University of Tokyo Faculty of Science Department of Physics
  • 1984 - 1988 University of Tokyo Faculty of Science Department of Physics
Professional career (1)：
  • phD (University of Tokyo)
Work history (8)：
  • 2019/07 - 現在 Okinawa Institute Science and Technology Graduate University Developmental Neurobiology Unit Professor
  • 2011/11 - 2019/06 Okinawa Institute of Science and Technology Graduate University Developmental Neurobiology Unit Associate Professor
  • 2006/10 - 2011/10 Okinawa Institute Science and Technology Promotion Corporation Developmental Neurobiology Unit Principal Investigator (Unit leader)
  • 2001/10 - 2006/09 RIKEN Masai Initiative Research Unit Unit leader
  • 2000/10 - 2001/09 JST PRESTO (Recognition and Formation) PRESTO researcher
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Association Membership(s) (7)：
Association for Research in Vision and Ophthalmology (ARVO) ,  International Zebrafish Society ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  International Society for Eye Research (ISER) ,  THE JAPAN NEUROSCIENCE SOCIETY ,  JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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