Rchr
J-GLOBAL ID:201901010072437137   Update date: Aug. 20, 2024

TSUCHIYA Takaho

ツチヤ タカホ | TSUCHIYA Takaho
Affiliation and department:
Job title: Assistant Professor
Research field  (2): Biological, health, and medical informatics ,  Systems genomics
Research keywords  (7): 情報生命科学 ,  Systems Biology ,  Bioinformatics ,  スパースモデリング ,  Spatial transcriptome ,  Epigenome ,  Multi-omics
Research theme for competitive and other funds  (5):
  • 2020 - 2023 1細胞空間トランスクリプトームによる細胞内と細胞間の統合ネットワーク推定手法開発
  • 2020 - 2022 2型糖尿病の代謝アダプテーション
  • 2019 - 2021 集団ゲノムデータに基づき変異を避けることによる遺伝子治療用gRNA設計法の確立
  • 2019 - 2020 集団ゲノムデータに基づき変異を避けることによる遺伝子治療用gRNA設計手法の確立
  • 2014 - 2017 シグナル伝達の時間パターンから解明するリガンド選択的な遺伝子発現機構
Papers (16):
  • Ruochong Wang, Futaba Kato, Rio Yasui Watson, Aaron M Beedle, Jarrod A Call, Yugo Tsunoda, Takeshi Noda, Takaho Tsuchiya, Makoto Kashima, Ayuna Hattori, et al. The RNA-binding protein Msi2 regulates autophagy during myogenic differentiation. Life Science Alliance. 2024. 7. 5. e202302016-e202302016
  • Hideki Maehara, Toshiya Kokaji, Atsushi Hatano, Yutaka Suzuki, Masaki Matsumoto, Keiichi I. Nakayama, Riku Egami, Takaho Tsuchiya, Haruka Ozaki, Keigo Morita, et al. DNA hypomethylation characterizes genes encoding tissue-dominant functional proteins in liver and skeletal muscle. Scientific Reports. 2023. 13. 1
  • Saeko Tahara, Takaho Tsuchiya, Hirotaka Matsumoto, Haruka Ozaki. Transcription factor-binding k-mer analysis clarifies the cell type dependency of binding specificities and cis-regulatory SNPs in humans. BMC genomics. 2023. 24. 1. 597-597
  • Takaho Tsuchiya, Hiroki Hori, Haruka Ozaki. CCPLS reveals cell-type-specific spatial dependence of transcriptomes in single cells. Bioinformatics. 2022. 38. 21. 4868-4877
  • Toshiya Kokaji, Miki Eto, Atsushi Hatano, Katsuyuki Yugi, Keigo Morita, Satoshi Ohno, Masashi Fujii, Ken-ichi Hironaka, Yuki Ito, Riku Egami, et al. In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states. Scientific Reports. 2022. 12. 1
more...
MISC (8):
  • Saeko Tahara, Takaho Tsuchiya, Hirotaka Matsumoto, Haruka Ozaki. MOCCS profile analysis clarifies the cell type dependency of transcription factor-binding sequences and cis-regulatory SNPs in humans. bioRxiv. 2022
  • 土屋貴穂. Gene therapy based on genome editing technology and population genomics. BIO Clinica. 2021. Vol.36. 5. 448-452
  • Takaho Tsuchiya. Perspective of gene therapy based on genome editing technology and population genomics. Precision Medicine. 2021. Vol.4. 2. 167-171
  • Takaho Tsuchiya. Genome editing technology and population genomics for gene therapy. Medical Science Digest. 2020. Vol.46. 12. 766-770
  • Takaho Tsuchiya. Perspective of gene therapy and precision medicine based on population genomics. Precision Medicine. 2020. Vol.3. 10. 630-634
more...
Lectures and oral presentations  (21):
  • Predicting SNPs' effects on transcriptional factor binding and cell-type specificity using a crowd of ChIP-seq data
    (日本人類遺伝学会第67回大会)
  • MOCCS-DB: ヒト転写因子認識配列の多様性データベース
    (トーゴーの日シンポジウム2022)
  • MOCCS-DB: ヒト転写因子認識配列の多様性データベース
    (トーゴーの日シンポジウム)
  • MOCCS profile analysis clarifies the cell type dependency of transcription factor-binding sequences and cis-regulatory SNPs in humans
    (2022年日本バイオインフォマティクス学会年会・第11回生命医薬情報学連合大会(IIBMP2022))
  • MOCCSプロファイルで明らかにする、転写因子認識配列の細胞型特異性とヒト一塩基多型が 転写因子結合へ与える影響
    (2022年日本バイオインフォマティクス学会年会・第11回生命医薬情報学連合大会(IIBMP2022))
more...
Education (3):
  • 2014 - 2017 University of Tokyo Faculty of Science Department of Biological Sciences
  • 2012 - 2014 University of Tokyo Faculty of Science Department of Biophysics & Biochemistry
  • 2007 - 2012 Kyoto University Faculty of Science
Professional career (1):
  • Ph.D. (The University of Tokyo)
Work history (4):
  • 2019/05 - 現在 University of Tsukuba Center for Artificial Intelligence Research
  • 2019/05 - 現在 University of Tsukuba Department of Bioinformatics, Faculty Assistant Professor
  • 2017/04 - 2019/03 Astellas Pharma Inc. Associate
  • 2014/04 - 2017/03 Japan Society for the Promotion of Science Research Fellow (DC1)
Awards (3):
  • 2021/09 - 第10回 生命医薬情報学連合大会(IIBMP2021)Poster Award
  • 2020/09 - 第9回 生命医薬情報学連合大会(IIBMP2020)Poster Award
  • 2014/09 - 15th International Conference on Systems Biology Student Bursary Award
Association Membership(s) (2):
JAPANESE SOCIETY FOR BIOINFORMATICS ,  Japanese Society for Quantitative Biology
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