Research field (2)：
Pharmacology
, Clinical pharmacy
Research keywords (3)：
Transporter
, Platelet
, Prostanoid
Research theme for competitive and other funds (12)：
2024 - 2027 唾液中薬物濃度モニタリングが適用可能な薬物の選択方法の確立
2021 - 2023 がん細胞の増殖・薬物耐性における血小板の役割解明
2020 - 2021 がん細胞の薬物耐性獲得の機序解明とその回避に向けた検討
2018 - 2021 Elucidation of the role of prostanoids in the development of liver fibrosis
2019 - 2020 ヒト血小板の機能調節におけるプロスタグランジンF2αの役割解明
2017 - 2018 肝再生における血小板トロンボキサンA2受容体の役割解明
2014 - 2016 血小板機能調節におけるプロスタグランジンF2αの役割解明
2013 - 2015 Regulation of cardiac prostanoid synthesis by glucocorticoid and its pathophysiological meaning
2012 - 2013 PGI2受容体アゴニストの長期連用による作用減弱の機序解明
2011 - 2012 Roles of the prostanoids in the regulation of immunological responses
2010 - 2012 Roles of the prostanoids in the pathogenesis of cardiovascular diseases
2010 - 2011 プロスタグランジンE2受容体を介した新規血小板凝集抑制作用の解明
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Papers (47)：
Ryusei Mikami, Shungo Imai, Mineji Hayakawa, Hitoshi Kashiwagi, Yuki Sato, Shunsuke Nashimoto, Mitsuru Sugawara, Yoh Takekuma. Development and validation of the prediction score for augmented renal clearance in critically Ill Japanese adults. Journal of pharmaceutical health care and sciences. 2024. 10. 1. 69-69
Yuki Inoue, Hitoshi Kashiwagi, Yuki Sato, Shunsuke Nashimoto, Tsutomu Endo, Masahiko Takahata, Miki Komatsu, Mitsuru Sugawara, Yoh Takekuma. Clinical research for saliva-based therapeutic drug monitoring of linezolid. British journal of clinical pharmacology. 2024
Yuki Inoue, Hitoshi Kashiwagi, Yuki Sato, Shunsuke Nashimoto, Mitsuru Sugawara, Yoh Takekuma. Exploring the impact of baseline platelet count on linezolid-induced thrombocytopenia: a retrospective single-center observation study. International journal of clinical pharmacy. 2024
Chihiro Koseki, Takehiko Ishikawa, Yuki Sato, Mikiko Shimada, Yuki Yokoi, Kiminori Nakamura, Naoyuki Honma, Takanori Moriyama, Hitoshi Kashiwagi, Mitsuru Sugawara. Development of an Evaluation System Using Intestinal Organoids for Drug Efflux Transport Analysis by an Imaging Approach. Journal of Pharmaceutical Sciences. 2024
Potentiating effect of prostaglandin F<sub>2</sub>α on platelet aggregation in mice
(18th World Congress of Basic and Clinical Pharmacology (WCP2018) 2018)
Prostaglandin F<sub>2</sub>α potentiates platelet aggregation via prostaglandin E<sub>2</sub> and thromboxane A<sub>2</sub> receptors
(第90回日本薬理学会年会 2017)
1999 - 2003 Hokkaido University Faculty of Pharmaceutical Sciences
Professional career (1)：
Ph.D. (Hokkaido University)
Work history (3)：
2019/09 - 現在 Hokkaido University Faculty of Pharmaceutical Sciences
2012/04 - 2020/03 旭川高等看護学院 非常勤講師
2008/04 - 2019/08 Asahikawa Medical University School of Medicine
Committee career (3)：
2023/02 - 2024/01 日本薬学会北海道支部 若手シンポジウム実行委員
2021/02 - 2024/01 日本薬学会北海道支部 幹事
2022/02 - 2023/01 日本薬学会北海道支部 庶務幹事
Association Membership(s) (6)：
日本TDM学会
, THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN
, JAPANESE SOCIETY OF PHARMACEUTICAL HEALTH CARE AND SCIENCES
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, Japanese Association of Cardiovascular Pharmacology
, THE JAPANESE PHARMACOLOGICAL SOCIETY
