Rchr
J-GLOBAL ID:201901011028973290
Update date: Jun. 10, 2024
Yoshioka Hiromasa
Yoshioka Hiromasa
Affiliation and department:
Job title:
Special Postdoctoral Researcher
Research field (5):
Applied biochemistry
, Applied molecular and cellular biology
, Pharmaceuticals - chemistry and drug development
, Chemical biology
, Bioorganic chemistry
Research theme for competitive and other funds (4):
- 2024 - 2027 生体内で安定な人工金属触媒の開発と、組織特異的SQLE分解誘導剤合成への応用
- 2023 - 2026 組織選択的なタンパク質安定性制御方法の開発
- 2022 - 2024 Development of robust catalysts applicable in-blood synthesis and their application to tissue-specific drug synthesis.
- 2018 - 2020 Development of small molecules that modulate cholesterol homeostasis via ligand-mediated stabilization/destabilization.
Papers (13):
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Takatsugu Kasahara, Tsung-Che Chang, Hiromasa Yoshioka, Sayaka Urano, Yasuko Egawa, Michiko Inoue, Tsuyoshi Tahara, Koji Morimoto, Ambara R. Pradipta, Katsunori Tanaka. Anticancer approach by targeted activation of a global inhibitor of sialyltransferases with acrolein. Chemical Science. 2024
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Igor Nasibullin, Hiromasa Yoshioka, Akari Mukaimine, Akiko Nakamura, Yuriko Kusakari, Tsung-Che Chang, Katsunori Tanaka. Catalytic olefin metathesis in blood. Chemical Science. 2023
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Kawamura K, Yoshioka H, Sato C, Yajima T, Furuyama Y, Kuramochi K, Ohgane K. Fine-tuning of nitrogen-containing bisphosphonate esters that potently induce degradation of HMG-CoA reductase. Bioorganic & medicinal chemistry. 2022. 78
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Hiromasa Yoshioka, Tatsuro Kawamura, Makoto Muroi, Yasumitsu Kondoh, Kaori Honda, Makoto Kawatani, Harumi Aono, Herbert Waldmann, Nobumoto Watanabe, Hiroyuki Osada. Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1). ACS Chemical Biology. 2022. 17. 2. 483-491
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Ryuta Shioi, Fumika Karaki, Hiromasa Yoshioka, Tomomi Noguchi-Yachide, Minoru Ishikawa, Kosuke Dodo, Yuichi Hashimoto, Mikiko Sodeoka, Kenji Ohgane. Image-based screen capturing misfolding status of Niemann-Pick type C1 identifies potential candidates for chaperone drugs. PLOS ONE. 2020. 15. 12. e0243746
more...
MISC (4):
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吉岡広大. BOOKS紹介 実験医学別冊 論文図表を読む作法 はじめて出会う実験&解析法も正しく解釈!生命科学・医学論文をスラスラ読むためのFigure事典. MEDCHEM NEWS. 2024. 34. 2. 102-102
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Introducing Our Authors. ACS Chemical Biology. 2022. 17. 3. 493-494
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Hiromasa Yoshioka. コレステロール生合成の新たな制御ポイント. 生化学. 2021. 93. 1. 147-151
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Hiromasa Yoshioka. 細胞内で標的選択的に共有結合を形成するプロドラッグ. ファルマシア. 2021. 57. 2. 147-147
Lectures and oral presentations (27):
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がん細胞内で起こる[4+4]付加環化反応の生物学的な意義の解明に向けて
(日本化学会 第104春季年会 2024)
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フェロトーシスを制御する低分子化合物の探索
(第96回日本生化学会大会 2023)
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がん細胞内で起こる[4+4]付加環化反応の意義の解明に向けて
(第13回 CSJ化学フェスタ2023 2023)
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6-アザ-アルテミシニンのエナンチオ分岐合成およびケミカルプローブを用いた制がん機構研究
(2023年度若手支援技術講習会 2023)
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Targeted therapy for KRAS-mutant cancer using glycosylated artificial metalloenzymes via therapeutic in vivo synthetic chemistry
(2023)
more...
Works (1):
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Quantification of Gel Bands by an Image J Macro, Band/Peak Quantification Tool
Kenji Ohgane, Hiromasa Yoshioka 2019 -
Education (3):
- 2015 - 2020 The University of Tokyo Graduate School of Pharmaceutical Sciences
- 2011 - 2015 Yokohama City University
- 2008 - 2011 東京都市大学附属高等学校
Professional career (1):
Work history (6):
- 2024/04 - 現在 RIKEN Special Postdoctoral Researcher
- 2021/10 - 現在 Ochanomizu University Faculty of Science
- 2022/04 - 2024/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
- 2022/04 - 2024/03 RIKEN Biofunctional Synthetic Chemistry Laboratory Postdoctoral Researcher
- 2020/04 - 2022/03 RIKEN CSRS Chemical Biology research group post-doctoral researcher
- 2018/04 - 2020/03 Japan Society for the Promotion of Science, Research Fellowship for Young Scientists
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Association Membership(s) (3):
JAPANESE SOCIETY FOR CHEMICAL BIOLOGY
, THE JAPANESE BIOCHEMICAL SOCIETY
, THE PHARMACEUTICAL SOCIETY OF JAPAN
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