Rchr
J-GLOBAL ID:201901011746598898
Update date: Apr. 15, 2024
Sakai Yuji
サカイ ユウジ | Sakai Yuji
Affiliation and department:
Job title:
Program-Specific Associate Professor
Other affiliations (2):
-
The University of Tokyo
Graduate School of Medicine
Visiting Researcher
-
RIKEN
Interdisciplinary Theoretical and Mathematical Sciences Program
Visiting Researcher
Research field (4):
Cell biology
, Biophysics
, Genetics
, Bio-, chemical, and soft-matter physics
Research keywords (8):
Theoretical Biology
, Biophysics
, Cell Biology
, Molecular Biology
, Soft Matter Physics
, Organelle
, Chromosome
, Autophagy
Research theme for competitive and other funds (8):
- 2023 - 2027 Theoretical study of autophagic membrane dynamics
- 2023 - 2025 Theoretical study of intracellular degradation mechanisms
- 2023 - 2024 Elucidation of intracellular lipid transfer mechanism using molecular dynamics simulations
- 2020 - 2023 Theoretical study for mitotic chromosome assembly
- 2018 - 2020 Theoretical study of autophagy dynamics
- 2018 - 2020 Theoretical study of chromosome shaping and segregation
- 2013 - 2018 Elucidation of metabolic network underlying plant development
- 2009 - 2011 信頼性の高い有効模型によるQCD相構造の定量的解明
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Papers (41):
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Yuji Sakai, Satoru Takahashi, Ikuko Koyama-Honda, Chieko Saito, Noboru Mizushima. Experimental determination and mathematical modeling of standard shapes of forming autophagosomes. Nature communications. 2024. 15. 1. 91-91
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Tetsuya Kotani, Yuji Sakai, Hiromi Kirisako, Chika Kakuta, Soichiro Kakuta, Yoshinori Ohsumi, Hitoshi Nakatogawa. A mechanism that ensures non-selective cytoplasm degradation by autophagy. Nature Communications. 2023. 14. 1. 5815-5815
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Zi Yang, Saori R. Yoshii, Yuji Sakai, Haruka Chino, Roland L. Knorr, Noboru Mizushima. Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates. 2023
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Saori Shinoda, Yuji Sakai, Takahide Matsui, Masaaki Uematsu, Ikuko Koyama-Honda, Jun-ichi Sakamaki, Hayashi Yamamoto, Noboru Mizushima. Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation. eLife. 2023
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Yuji SAKAI. Mathematical Model of Membrane Deformation Dynamics in Autophagosome Formation. Seibutsu Butsuri. 2022. 62. 1. 50-52
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MISC (58):
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Yuji Sakai. Mathematical Model of Membrane Deformation Dynamics in Autophagosome Formation. 生物物理(Web). 2022. 62. 1
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Yuji Sakai, Satoru Takahashi, Ikuko Koyama-Honda, Chieko Saito, Noboru Mizushima. Modeling membrane morphogenesis in autophagosome formation. 日本数理生物学会年会(Web). 2022. 32nd
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境祐二. Modeling mitotic chromosome organization and segregation mediated by condensins. 月刊細胞. 2022. 54. 11
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境 祐二. オートファゴソーム形成の膜変形ダイナミクスの数理モデル. 生物物理. 2022. 62. 1. 50-52
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小山 郁子[本田], 境 祐二, 立川 正志, 田村 律人, 水島 昇. 神経系におけるオルガネラコミュニケーションとダイナミクス オートファゴソーム膜の形態と物理モデル. 日本生化学会大会プログラム・講演要旨集. 2020. 93回. [1S06e-05]
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Lectures and oral presentations (4):
-
Experimental determination and theoretical model of standard shapes of forming autophagosomes
(ICBP 2023 - International Conference on Biological Physics 2023)
-
Molecular dynamics of autophagosomal lipid transfer Atg2
(CCP2023 - 34th IUPAP Conference on Computational Physics 2023)
-
オートファゴソーム形成の数理モデル
(ERATO 水島細胞内分解ダイナミクスプロジェクト 最終シンポジウム「細胞内分解研究の未来を拓く」 2023)
-
分裂期染色体形成の数理モデル
(第75回日本細胞生物学会大会 2023)
Education (1):
- 2007 - 2012 Kyushu University Graduate School of Science Department of Physics
Professional career (1):
- Ph.D (Science) (Kyushu University)
Work history (7):
- 2022/04 - 現在 Kyoto University Institute for Frontier Life and Medical Sciences Program-Specific Associate Professor
- 2017/04 - 2022/03 The University of Tokyo Graduate School of Medicine Assistant Professor
- 2014/04 - 2022/03 Seikei University Faculty of Science and Technology Lecturer (part-time)
- 2015/04 - 2017/03 RIKEN Interdisciplinary Theoretical and Mathematical Sciences Program
- 2014/04 - 2016/03 RIKEN
- 2012/04 - 2014/03 RIKEN RIKEN Nishina Center for Accelerator-Based Science
- 2009/04 - 2012/03 Kyushu University Faculty of Sciences Department of Physics Research Fellow, Japan Society for the Promotion of Science (DC1)
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