Suginobe Hidehiro

Research field (1)： Fetal medicine/Pediatrics

Research theme for competitive and other funds (2)：

2020 - 2023 エクソソームプロファイリングによるダウン症候群の肺高血圧症発症病態の解明
2017 - 2020 The mechanisms of pulmonary hypertension in Down syndrome by iPSC technology

Papers (22)：

Renjie Wang, Moyu Hasegawa, Hidehiro Suginobe, Chika Yoshihara, Yoichiro Ishii, Atsuko Ueyama, Kazutoshi Ueda, Kazuhisa Hashimoto, Masaki Hirose, Ryo Ishii, et al. Impaired Relaxation in Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Pathogenic TNNI3 Mutation of Pediatric Restrictive Cardiomyopathy. Journal of the American Heart Association. 2024. 13. 6. e032375
Hidehiro Suginobe, Hidekazu Ishida, Yoichiro Ishii, Kazutoshi Ueda, Chika Yoshihara, Atsuko Ueyama, Renjie Wang, Hirofumi Tsuru, Kazuhisa Hashimoto, Masaki Hirose, et al. Isogenic pairs of induced-pluripotent stem-derived endothelial cells identify DYRK1A/PPARG/EGR1 pathway is responsible for Down syndrome-associated pulmonary hypertension. Human molecular genetics. 2023
Hidekazu Ishida, Jun Narita, Ryo Ishii, Hidehiro Suginobe, Hirofumi Tsuru, Renjie Wang, Chika Yoshihara, Atsuko Ueyama, Kazutoshi Ueda, Masaki Hirose, et al. Clinical Outcomes and Genetic Analyses of Restrictive Cardiomyopathy in Children. Circulation. Genomic and precision medicine. 2023. e004054
Hirofumi Tsuru, Chika Yoshihara, Hidehiro Suginobe, Mizuki Matsumoto, Yoichiro Ishii, Jun Narita, Ryo Ishii, Renjie Wang, Atsuko Ueyama, Kazutoshi Ueda, et al. Pathogenic Roles of Cardiac Fibroblasts in Pediatric Dilated Cardiomyopathy. Journal of the American Heart Association. 2023. e029676
石田秀和, 成田淳, 石井良, 廣瀬将樹, 橋本和久, 杉辺英世, 吉原千華, 上山敦子, 大薗恵一. 肝移植を行った小児門脈性肺高血圧症の中期予後. 日本肺高血圧・肺循環学会学術集会・日本小児肺循環研究会プログラム・抄録集. 2022. 7回・28回. 155-155

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