Rchr
J-GLOBAL ID：201901012096601356   Update date: Sep. 29, 2025

Hirahara Shuichiro

ヒラハラ シュウイチロウ | Hirahara Shuichiro
Affiliation and department：
Nagoya City University Graduate School of Medical Sciences Department of Ophthalmology and Visual Science

About Nagoya City University Graduate School of Medical Sciences Department of Ophthalmology and Visual Science


Research field  (1)： Ophthalmology
Research theme for competitive and other funds  (4)：
  • 2022 - 2025 Elucidation of roles of mast cells and macrophages in the pathogenesis of age-related macular degeneration
  • 2022 - 2025 Elucidation of roles of mast cells and macrophages in the pathogenesis of age-related macular degeneration
  • 2020 - 2024 ケモカイン受容体を標的とした萎縮型加齢黄斑変性制御機構の解明と新規治療法の開発
  • 2016 - 2019 Chemokine receptor as therapeutic target in ocular angiogenesis
Papers (24)：
  • Ryan D Makin, Ivana Apicella, Roshni Dholkawala, Shinichi Fukuda, Shuichiro Hirahara, Yoshio Hirano, Younghee Kim, Ayami Nagasaka, Yosuke Nagasaka, Siddharth Narendran, et al. Inflammasome activation aggravates choroidal neovascularization. Angiogenesis. 2024. 27. 4. 919-929
  • Yukinori Sakaeda, Aki Kato, Soichiro Kuwayama, Shuichiro Hirahara, Norihiro Suzuki, Yuichiro Ogura, Yoko Nakazawa, Tsutomu Yasukawa. Long-Term Prognosis of Patients with Polypoidal Choroidal Vasculopathy Treated with Photodynamic Therapy. Journal of clinical medicine. 2023. 12. 14
  • Shao-Bin Wang, Siddharth Narendran, Shuichiro Hirahara, Akhil Varshney, Felipe Pereira, Ivana Apicella, Meenakshi Ambati, Vidya L Ambati, Praveen Yerramothu, Kameshwari Ambati, et al. DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Science immunology. 2021. 6. 66. eabi4493
  • 榮枝 幸紀, 安川 力, 加藤 亜紀, 桑山 創一郎, 平原 修一郎, 鈴木 識裕, 高瀬 範明, 吉田 宗徳, 小椋 祐一郎. 滲出性加齢黄斑変性症に対する光線力学的療法の長期予後. 眼科臨床紀要. 2021. 14. 11. 763-764
  • Shinichi Fukuda, Siddharth Narendran, Akhil Varshney, Yosuke Nagasaka, Shao-Bin Wang, Kameshwari Ambati, Ivana Apicella, Felipe Pereira, Benjamin J Fowler, Tetsuhiro Yasuma, et al. Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity. Science advances. 2021. 7. 40. eabj3658
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MISC (28)：
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Education (1)：
  • - 2005 Nagoya City University
Professional career (1)：
  • 医学博士 (名古屋市立大学)
Work history (9)：
  • 2023/04 - 現在 名古屋市立大学大学院医学研究科 眼科 客員准教授
  • 2021 - 名古屋市立大学大学院医学研究科 眼科 非常勤講師, 研究員
  • 2019/04 - Nagoya City University
  • 2019 - 豊田厚生病院 眼科 医長
  • 2016 - バージニア大学 眼科 Center for Advanced Vision and Science 博士研究員
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