Saika Fumihiro

Affiliation and department：

Research field (1)： Pharmacology

Research keywords (14)：抗悪性腫瘍薬起因性神経障害性疼痛 , CPP , コカイン , メタンフェタミン , 薬物依存 , 痒み , 神経障害性疼痛 , ケモカイン , サイトカイン , 脊髄 , マクロファージ , ミクログリア , 慢性疼痛 , DREADD

Research theme for competitive and other funds (7)：

2021 - 2024 糖尿病における小胞体ストレス応答とSUMO化
2020 - 2023 Molecular mechanisms of nociceptive somatosensory disorders revealed by a novel regulatory method of microglia
2020 - 2023 乾癬に付随した難治性のかゆみの分子基盤解明
2017 - 2021 Elucidation of drug dependence formation / relapse molecular mechanism focusing on neuroinflammation
2016 - 2019 Pathogenesis of neuropathic pain due to interaction between peripheral and central sensitization

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Papers (55)：

Fumihiro Saika, Yohji Fukazawa, Yu Hatano, Shiroh Kishioka, Yuko Hino, Shinjiro Hino, Kentaro Suzuki, Norikazu Kiguchi. Sexually dimorphic effects of pexidartinib on nerve injury-induced neuropathic pain in mice. Glia. 2024
Fumihiro Saika, Yohji Fukazawa, Shiroh Kishioka, Norikazu Kiguchi. Characterization of spinal microglial activation in a mouse model of imiquimod-induced psoriasis. Journal of Pharmacological Sciences. 2023. 153. 4. 183-187
Daichi Kobayashi, Tomoya Watarai, Madoka Ozawa, Yasuhiro Kanda, Fumihiro Saika, Norikazu Kiguchi, Arata Takeuchi, Masahito Ikawa, Shinsuke Matsuzaki, Tomoya Katakai. Tas2R signaling enhances mouse neutrophil migration via a ROCK-dependent pathway. Frontiers in Immunology. 2022. 13
Norikazu Kiguchi, Yohji Fukazawa, Ayano Saika, Daisuke Uta, Fumihiro Saika, Tomoe Y. Nakamura, Mei-Chuan Ko, Shiroh Kishioka. Chemogenetic activation of central gastrin-releasing peptide-expressing neurons elicits itch-related scratching behavior in male and female mice. Pharmacology Research & Perspectives. 2021. 9. 3
Fumihiro Saika, Shinsuke Matsuzaki, Shiroh Kishioka, Norikazu Kiguchi. Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice. Cells. 2021. 10. 4

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MISC (30)：

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Education (2)：

Professional career (1)：

Work history (2)：

Committee career (1)：

Awards (4)：

Association Membership(s) (1)：

THE JAPANESE PHARMACOLOGICAL SOCIETY

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