Rchr
J-GLOBAL ID:201901012378170897   Update date: Oct. 12, 2021

Mishima Yuta

ミシマ ユウタ | Mishima Yuta
Affiliation and department:
Job title: 助教
Homepage URL  (1): https://www.linkedin.com/in/yutamishima/
Research field  (1): Cell biology
Research keywords  (6): Biomedical engineering ,  Regulatory Science ,  Industry-academia collaboration ,  Tumor immunology ,  Epigenetics ,  Regenerative medicine
Research theme for competitive and other funds  (8):
  • 2020 - 2023 がん免疫療法の評価を可能とする3次元がんモデルの構築
  • 2020 - 2022 iPS細胞由来CAR-T細胞を用いた固形がんに対する傷害機能向上技術の開発
  • 2017 - 2020 患者由来がん組織を培養可能なデバイスの開発とがん免疫療法の評価法の構築
  • 2016 - 2019 iPS 細胞由来再生 T 細胞とがん特異抗原レセプター遺伝子導入による免疫療法の開発
  • 2016 - 2018 免疫再生治療に向けた胸腺模倣デバイスの開発
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Papers (7):
  • Shoichi Iriguchi, Yutaka Yasui, Yohei Kawai, Suguru Arima, Mihoko Kunitomo, Takayuki Sato, Tatsuki Ueda, Atsutaka Minagawa, Yuta Mishima, Nariaki Yanagawa, et al. A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy. Nature Communications. 2021. 12. 1
  • Hiroaki Mashima, Rong Zhang, Tsuyoshi Kobayashi, Yuichiro Hagiya, Hirotake Tsukamoto, Tianyi Liu, Tatsuaki Iwama, Masateru Yamamoto, Chiahsuan Lin, Ryusuke Nakatsuka, et al. Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response. OncoImmunology. 2020. 9. 1. 1814620-1814620
  • Yu-suke Torisawa, Yuta Mishima, Shin Kaneko. Developing thymus-on-a-chip and cancer-on-a-chip for cancer immunotherapy. Impact. 2019
  • Yuta Mishima, Changshan Wang, Satoru Miyagi, Atsunori Saraya, Hiroyuki Hosokawa, Makiko Mochizuki-Kashio, Yaeko Nakajima-Takagi, Shuhei Koide, Masamitsu Negishi, Goro Sashida, et al. Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development. NATURE COMMUNICATIONS. 2014. 5
  • Makiko Mochizuki-Kashio, Yuta Mishima, Satoru Miyagi, Masamitsu Negishi, Atsunori Saraya, Takaaki Konuma, Jun Shinga, Haruhiko Koseki, Atsushi Iwama. Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells. BLOOD. 2011. 118. 25. 6553-6561
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MISC (1):
Patents (2):
  • Hematopoietic progenitor cell marker
  • 皮膚用粘着シート
Books (1):
  • 『生物の科学 遺伝』
    株式会社エヌ・ティー・エス 2017
Lectures and oral presentations  (17):
  • MODELING CANCER IMMUNOTHERAPY IN A PERFUSABLE 3D VASCULARIZED TUMOR-ON-A-CHIP USING HLA-KO UNIVERSAL HUMAN IPSC-DERIVED ENDOTHELIAL CELLS
    (ISSCR 2020 Virtual 2020)
  • Modeling cancer immunotherapy in a perfusable 3D vascularized tumor-on-a-Chip using universal iPSC-derived endothelial cells.
    (CiRA 2019 International Symposium 2019)
  • iPS細胞とレギュラトリーサイエンス
    (順天堂大学医学部 医療の経済学 第10回講義 2019)
  • iPS細胞が作り出す社会とビジネス
    (関⻄大学 商学部新入生歓迎特別行事講演 2019)
  • がんと再生医療
    (つくば再生医療・細胞治療カンファレンス講演会 2019)
more...
Professional career (1):
  • 博士(医薬学)
Work history (7):
  • 2021/04 - 現在 University of Tsukuba Hospital Department of Regenerative Medicine Deputy Director
  • 2020/03 - 現在 University of Tsukuba Faculty of Medicine Assistant Professor
  • 2017/04 - 2020/02 Kyoto University Center for iPS cell Research and Application (CiRA) T-CiRA program, Kaneko Project Sub-PI
  • 2016/04 - 2019/03 Japan society for the promotion of science (JSPS) JSPS Research Fellow
  • 2013/06 - 2016/06 Beth Israel Deaconess Medical Center / Harvard Medical School (BIDMC/HMS) Hematology / Oncology Research fellow
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Committee career (1):
  • 2017/04 - 2020/03 バイオインダストリー協会 バイオサイエンスとインダストリー編集委員会 再生医療トピックス委員
Awards (8):
  • 2013/06 - The Uehara Memorial Foundation Uehara postdoctoral fellowship
  • 2013/03 - 千葉大学大学院 医学薬学府長賞(首席)
  • 2012/12 - 千葉大学 G-COE プログラム Annual Best Research Award
  • 2012/09 - 東京エレクトロンデバイス株式会社 第1回 Microsoft Kinnect for Windows Contest 技術賞
  • 2012/03 - 日本薬学会 優秀発表賞(第13回 Pharmaco-hematology シンポジウム)
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Association Membership(s) (3):
Japanese Cancer Association ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  International Society of Stem Cell Research (ISSCR)
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