Rchr
J-GLOBAL ID:201901012679368528   Update date: Aug. 29, 2024

Hozumi Isao

ホズミ イサオ | Hozumi Isao
Affiliation and department:
Other affiliations (1):
Research field  (1): Neurology
Research theme for competitive and other funds  (15):
  • 2019 - 2024 Studies on stem cell differentiation and growth process in neurodegenerative diseases focusing on biometals
  • 2017 - 2021 Research on the molecular mechanism of intracranial calcification and novel therapies
  • 2017 - 2020 Novel therapeutic strategies for amyotrophic lateral sclerosis using human deciduous dental pulp stem cells and their active ingredients
  • 2016 - 2019 Investigation on pathomechanism and treatment of canine degenerative myelopathy using disease-specific iPS cell
  • 2015 - 2017 Pathogenic mechanism of neurodegenerative diseases associated with dysfunction of ubiquitin ligase
Show all
Papers (85):
  • Hisaka Kurita, Haruka Masuda, Ayu Okuda, Suzuna Go, Kazuki Ohuchi, Hiroki Yoshioka, Masatake Fujimura, Isao Hozumi, Masatoshi Inden. Epigenetic alternations in the SYP and DLG4 genes due to low-level methylmercury exposure during neuronal differentiation in vitro. Journal of applied toxicology : JAT. 2024
  • Junya Murata, Kazuki Ohuchi, Yuto Murayama, Ayane Mishima, Hisaka Kurita, Isao Hozumi, Masatoshi Inden. TIC10/ONC201 Enhances Phosphate Uptake in the Human Neuroblastoma Cell Line SH-SY5Y. BPB Reports. 2024. 7. 4. 96-100
  • Hisaka Kurita, Misa Ueda, Miyu Kimura, Ayu Okuda, Kazuki Ohuchi, Isao Hozumi, Masatoshi Inden. Zinc Deficiency Decreases Neurite Extension via CRMP2 Signal Pathway. Biological & pharmaceutical bulletin. 2024. 47. 4. 796-800
  • Ayaka Fujimaki, Kazuki Ohuchi, Shinnosuke Takizawa, Takanori Murakami, Hisaka Kurita, Isao Hozumi, Xiaopeng Wen, Yoshihisa Kitamura, Zhiliang Wu, Yoichi Maekawa, et al. The neuroprotective effects of FG-4592, a hypoxia-inducible factor-prolyl hydroxylase inhibitor, against oxidative stress induced by alpha-synuclein in N2a cells. Scientific Reports. 2023. 13. 1
  • Suzuna Go, Haruka Masuda, Mizuki Tsuru, Masatoshi Inden, Isao Hozumi, Hisaka Kurita. Exposure to a low concentration of methylmercury in neural differentiation downregulates NR4A1 expression with altered epigenetic modifications and inhibits neuronal spike activity in vitro. Toxicology Letters. 2023. 374. 68-76
more...
MISC (96):
  • 中島 健二, 祖父江 元, 長谷川 一子, 饗場 郁子, 青木 正志, 阿部 康二, 池内 健, 小野寺 理, 梶 龍兒, 吉良 潤一, et al. Huntington病の診断、治療、療養の手引き. 神経治療学. 2020. 37. 1. 61-104
  • 山田 恵, 田中 真生, 金子 雅幸, 二宮 勇平, 栗田 尚佳, 位田 雅俊, 林 祐一, 石浦 浩之, 三井 純, 岩田 淳, et al. 本邦における特発性基底核石灰化症(IBGC)の臨床的・遺伝学的検討(第2報). 臨床神経学. 2016. 56. Suppl. S287-S287
  • Sekine S, Kondo T, Miki K, Yoshida Y, Kurita H, Inden M, Hozumi I, Inoue H. Modeling idiopathic basal ganglia calcification using patient iPSCs. 57th Annual Meeting of the Japanese Society of Neurology, Kobe. 2016
  • 亀井 孝紀, 位田 雅俊, 関根 信一郎, 栗田 尚佳, 柴田 敏之, 保住 功. 家族性特発性基底核石灰化症の患者由来iPS細胞の作製と機能解析. 日本薬学会年会要旨集. 2016. 136年会. 3. 163-163
  • 山田 恵, 田中 真生, 高木 麻里, 小林 清樹, 田口 芳治, 高嶋 修太郎, 田中 耕太郎, 峠 哲男, 初田 裕幸, 村山 繁雄, et al. 本邦における特発性大脳基底核石灰化症の臨床的・遺伝学的検討. 臨床神経学. 2014. 54. Suppl. S66-S66
more...
Professional career (1):
  • 医学博士 (新潟大学)
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page