Rchr
J-GLOBAL ID：201901012813025853
Update date: Oct. 01, 2024
Itoh Hiroaki
イトウ ヒロアキ | Itoh Hiroaki
Affiliation and department：
Research field (1)：
Obstetrics and gynecology
Research keywords (3)：
周産期医学
, Developmental Origins of Health and Disease (DOHaD)
, 羊水塞栓症
Research theme for competitive and other funds (47)：
- 2024 - 2028 羊水塞栓症発症ハイリスク妊婦スクリーニング遺伝子パネル検査の開発を目指した研究
- 2023 - 2026 糖鎖生物学に注目した子宮体がん悪性化機構の解明とそのトランスレーショナルリサーチ
- 2022 - 2026 胎児血液中の脂質プロファイルが胎盤発達と乳児の身体及び神経発達に及ぼす影響
- 2022 - 2025 帝王切開時の分娩後出血を減らす-オキシトシン子宮筋注の子宮収縮維持効果の解析
- 2022 - 2025 機能障がいに焦点をあてた神経発達症の診断体系の再構成
- 2020 - 2025 母体腸管由来因子による代謝・免疫系のインプリンティング機構の解明
- 2020 - 2024 妊婦のエネルギー摂取不足に起因する成長後の児の脂肪肝発症リスク軽減を目指して
- 2020 - 2024 羊水塞栓症の遺伝的リスク背景ならびに発症機序の解明:新たな治療戦略を目指して
- 2021 - 2023 無痛分娩をうけた母児の長期予後~懸念の払しょくからアドバンテージの探索へ
- 2019 - 2022 Development of life-saving treatment for amniotic fluid embolism by intratracheal adrenalin administration
- 2018 - 2022 New perinatal management during labor with finger mounted near-infrared spectroscopy sensor and fetal heart rate monitoring
- 2018 - 2021 Identification of intestinal, vaginal and uterine lumen flora that are effective in maintaining pregnancy
- 2018 - 2021 A basic study on the reaction system of amniotic fluid fetal component and maternal for the pathogenesis of amniotic fluid embolism
- 2016 - 2019 The association between placental pathology and infantile growth
- 2015 - 2019 Development of a new intrapartum fetal monitoring technique using a finger-mounted fetal tissue oximeter: a multicenter study
- 2014 - 2017 analysis of the amount of bleeding in delivery through morphological changes at the placental basal plate in assisted reproductive technology
- 2013 - 2017 Measurement of maternal cerebral tissue hemoglobin on near-infrared time-resolved spectroscopy
- 2015 - 2017 胎生期低栄養が小胞体ストレス応答を介して成人期の脂肪蓄積リスクとなる機序の解析
- 2013 - 2016 An application of imaging mass spectrometry to the analysis of human placental villous structure –In search of etiology-specific biopolymer-
- 2012 - 2016 Study of the efficacy of the replacement therapy of zinc in pregnant women and the fetal environment
- 2011 - 2014 Development of therapy for endometriosis.
- 2012 - 2014 胎生期低栄養と良好な授乳期発育が成人期の生活習慣病発症におよぼす影響の基礎的解析
- 2011 - 2012 An application of imaging mass spectrometry to human placentas
- 2010 - 2012 A basic study on the effects of fetal circulation have on the placenta oxygenation dynamics by near-infrared spectroscopy
- 2009 - 2011 Elucidation of biological basis of autism as fatty acid metabolic disease
- 2009 - 2011 脂肪組織を核とした臓器間クロストークの視点から成人病胎児起源説の基礎的解析
- 2009 - 2010 非侵襲的胎児パルスオキシメーターの開発
- 2008 - 2010 Study on the relationship between increase of low-birth weight babies and the nutrition of pregnant women
- 2008 - 2010 Targeted drug delivery to tumor endothelial surface.
- 2006 - 2006 メタボリックシンドローム発症における胎生期栄養環境の関与の研究と予防戦略の開発
- 2005 - 2006 胎生期の低栄養状態が乳幼児期のエネルギー代謝調節機構におよぼす影響の検討
- 2005 - 2006 Role of adipose tissue derived factors in energy metabolism of intrauterine growth restricted offspring
- 2005 - 2006 Study of placental formation and functional differentiation by tissue specific stem cell transplantation
- 2005 - 2006 An experimental and clinical study on the development of adult disease in offspring with intrauterine undernutrition
- 2004 - 2005 胎生期の栄養異常が成人期の生活習慣病発症リスク因子となる機序とその予防の研究
- 2003 - 2004 An Experimental and Clinical Study of the Role of Intrauterine Undernutrition in the Development of Adult Diseases
- 2002 - 2004 子宮頚部への白血球遊走制御:ケモカイン受容体阻害剤による早産治療薬開発の試み
- 2003 - 2003 サル栄養膜幹細胞を用いた免疫寛容性生体膜の開発に関する基礎検討 -再生医学および細胞移植への臨床応用を目指して-
- 2002 - 2003 胎盤由来物質による母体エネルギー代謝調節および胎児への糖供給調節機構の解析
- 2001 - 2003 Exploratory study on drugs for regulation of uterine cervical ripening based on the biochemical analysis of extracellular matrix metabolism in the uterine cervix
- 2001 - 2002 Molecular Bidogical Analysis of Prostaglandin Synthesis in The Pregnant Myometrium and Fetal Membrane
- 2001 - 2002 A comprehensive study on the pathophysiology of fetal growth restriction based on the cell biological analysis of development of placental vascular system
- 2000 - 2001 妊娠時胎盤絨毛細胞の浸潤による子宮ラセン動脈の破壊と再構築機序の細胞生物学的解析
- 1999 - 2000 Biochemical and Molecular Biological Investigation of the Pregnancy Associated Uterine Blood Flow Increase-As a Basic Study for Developing Future Treatment of Intrauterine Growth Retardation-
- 1999 - 2000 A comprehensive study on the role of the obese gene product, leptin in reproduction and fetal development
- 1995 - 1995 妊娠におけるナトリウム利尿ペプチドの病態生理的意義の検討
- 1994 - 1995 A Biochemical Study on the Role of Amnion and Decidua Vera Tissues in the Maintenance of Human Pregnancy
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Papers (270)：
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Tomoaki Oda, Naoaki Tamura, Rui Ide, Kenta Kawai, Megumi Narumi, Masako Matsumoto, Yukiko Kohmura-Kobayashi, Naomi Furuta-Isomura, Chizuko Yaguchi, Toshiyuki Uchida, et al. Postpartum acute myometritis suppresses expression of contraction-associated proteins in the gravid uterus. Journal of reproductive immunology. 2024. 165. 104299-104299
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Machiko K. Asaka, Tomoko Nishimura, Hitoshi Kuwabara, Hiroaki Itoh, Nagahide Takahashi, Kenji J. Tsuchiya. Interleukin-23 levels in umbilical cord blood are associated with neurodevelopmental trajectories in infancy. PLOS ONE. 2024. 19. 4. e0301982-e0301982
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Tomoaki Oda, Naoaki Tamura, Daisuke Yata, Ayako Oda-Kishimoto, Toshiya Itoh, Naohiro Kubota, Yasuyuki Suzuki, Naohiro Kanayama, Hiroaki Itoh. A Case of Consumptive Coagulopathy Before Cardiopulmonary Failure in Amniotic Fluid Embolism and Review of Literature: A Perspective of the Latent Onset and Progression of Coagulopathy. Cureus. 2024. 16. 3. e55961
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Rui Ide, Tomoaki Oda, Yusuke Todo, Kenta Kawai, Masako Matsumoto, Megumi Narumi, Yukiko Kohmura-Kobayashi, Naomi Furuta-Isomura, Chizuko Yaguchi, Toshiyuki Uchida, et al. Comparative analysis of hyperfibrinolysis with activated coagulation between amniotic fluid embolism and severe placental abruption. Scientific reports. 2024. 14. 1. 272-272
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Nagahide Takahashi, Tomoko Nishimura, Taeko Harada, Akemi Okumura, Toshiki Iwabuchi, Md Shafiur Rahman, Hitoshi Kuwabara, Shu Takagai, Noriyoshi Usui, Manabu Makinodan, et al. Interaction of genetic liability for attention deficit hyperactivity disorder (ADHD) and perinatal inflammation contributes to ADHD symptoms in children. Brain, Behavior, & Immunity - Health. 2023. 30. 100630-100630
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MISC (243)：
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Chizuko Yaguchi, Megumi Ueda, Yuri Mizuno, Chie Fukuchi, Masako Matsumoto, Naomi Furuta-Isomura, Hiroaki Itoh. Association of Placental Pathology with Physical and Neuronal Development of Infants: A Narrative Review and Reclassification of the Literature by the Consensus Statement of the Amsterdam Placental Workshop Group. Nutrients. 2024. 16. 11
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伊東宏晃, 鈴木美沙子, 上田めぐみ, 伊藤昌彦, 望月和樹, 幸村友季子. 胎生期低栄養とメタボリックシンドローム発症リスク Developmental Origins of Metaflammationの視点から. DOHad研究(Web). 2022. 10. 2
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Hiroaki Itoh, Megumi Ueda, Misako Suzuki, Yukiko Kohmura-Kobayashi. Developmental Origins of Metaflammation; A Bridge to the Future Between the DOHaD Theory and Evolutionary Biology. Frontiers in endocrinology. 2022. 13. 839436-839436
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伊藤 敏谷, 山田 智史, 針山 孝彦, 奥寺 康司, 椙村 春彦, 伊東 宏晃, 岩下 寿秀, 目黒 史織, 河崎 秀陽. ナノスーツ-CLEM法を利用したパラフィン切片中に存在するウイルス粒子観察. 日本病理学会会誌. 2021. 110. 1. 338-338
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Tessa J Roseboom, Susan E Ozanne, Keith M Godfrey, Carmen R Isasi, Hiroaki Itoh, Rebecca Simmons, Amita Bansal, Mary Barker, Torsten Plosch, Deb M Sloboda, et al. Unheard, unseen and unprotected: DOHaD council's call for action to protect the younger generation from the long-term effects of COVID-19. Journal of developmental origins of health and disease. 2021. 12. 1. 3-5
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Education (1)：
- - 1986 Kyoto University Faculty of Medicine Department of Medical Science
Professional career (1)：
Work history (1)：
- 2018/11 - 現在 Hamamatsu University School of Medicine Obstetrics and Gynecology Professor
Awards (4)：
- 2011/06 - 第13回神澤医学賞
- 2008/04 - Best Reviewer Award 2007, The Journal of Obstetrics and Gynecology Research
- 2005/07 - 第13回臨床医科学フオーラム、井村特別賞
- 2005/04 - 第57回日本産科婦人科学会、優秀演題賞
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