Rchr
J-GLOBAL ID：201901012847446840   Update date: Aug. 18, 2024

Hirota Toru

Hirota Toru
Affiliation and department：
Japanese Foundation for Cancer Research Cancer Institute, Division of Experimental Pathology

About Japanese Foundation for Cancer Research Cancer Institute, Division of Experimental Pathology


Homepage URL  (1)： https://www.jfcr.or.jp/tci/exppathol/
Research field  (2)： Genetics ,  Tumor biology
Research theme for competitive and other funds  (29)：
  • 2024 - 2029 Biological Cluster: dynamic assembly and functional properties of supramolecular complexes in cells
  • 2024 - 2029 How biological cluster is assembled at centromeres in mitosis
  • 2022 - 2027 Plastic regulation of chromosome dynamics in cancer
  • 2022 - 2026 Regulation of mitotic chromosomes via liquid-liquid phase separation between RNA and chromosome scaffold proteins
  • 2022 - 2026 RNAと染色体骨格タンパク質群による液-液相分離現象が促すM期染色体制御
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Papers (87)：
  • Kosuke Sako, Ayako Furukawa, Ryu-Suke Nozawa, Jun-Ichi Kurita, Yoshifumi Nishimura, Toru Hirota. Bipartite binding interface recruiting HP1 to chromosomal passenger complex at inner centromeres. The Journal of cell biology. 2024. 223. 9
  • Masatoshi Hara, Mariko Ariyoshi, Tomoki Sano, Ryu-Suke Nozawa, Soya Shinkai, Shuichi Onami, Isabelle Jansen, Toru Hirota, Tatsuo Fukagawa. Centromere/kinetochore is assembled through CENP-C oligomerization. Molecular Cell. 2023. 83. 13. 2188-2205.e13
  • Keitaro Shimozaki, Izuma Nakayama, Toru Hirota, Kensei Yamaguchi. Current Strategy to Treat Immunogenic Gastrointestinal Cancers: Perspectives for a New Era. Cells. 2023. 12. 7
  • Yasutaka Kakui, Christopher Barrington, Yoshiharu Kusano, Rahul Thadani, Todd Fallesen, Toru Hirota, Frank Uhlmann. Chromosome arm length, and a species-specific determinant, define chromosome arm width. Cell reports. 2022. 41. 10. 111753-111753
  • Norihisa Shindo, Kazuki Kumada, Kenji Iemura, Jun Yasuda, Haruna Fujimori, Mai Mochizuki, Keiichi Tamai, Kozo Tanaka, Toru Hirota. Autocleavage of separase suppresses its premature activation by promoting binding to cyclin B1. Cell reports. 2022. 41. 9. 111723-111723
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MISC (179)：
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Patents (2)：
Professional career (1)：
  • 医学博士 (新潟大学)
Work history (4)：
  • 2005/10 - 現在 Japanese Foundation for Cancer Research
  • 2004/04 - 2005/09 JSPS Postdoctral Fellowship for Research Abroad.
  • 2001/04 - 2004/03 JSPS Research Fellow (PD)
  • 1996/04 - 2000/09 Niigata University Graduate School of Medical Science
Awards (3)：
  • 2022/01 - がん研究会学術賞
  • 2006/10 - Japanese Cancer Association The Young Investigator Awards
  • 2006/08 - Niigata University Yujinkinen Gakujutsu Shorei Prize
Association Membership(s) (2)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE CANCER ASSOCIATION
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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