Rchr
J-GLOBAL ID：201901013703926762
Update date: Jun. 25, 2024
Amatsu Sho
アマツ ショウ | Amatsu Sho
Affiliation and department：
Research field (2)：
Applied microbiology
, Bacteriology
Research theme for competitive and other funds (4)：
- 2023 - 2026 Mechanism of Intestinal Absorption of Hyper-virulent Botulinum Toxin Complex
- 2020 - 2023 Analysis of transport mechanism of hemagglutinin of botulinum toxin complex to adherens junctions
- 2018 - 2020 B型ボツリヌス毒素複合体の腸管吸収機構の解明
- 2015 - 2018 ボツリヌス毒素複合体の宿主侵入機構に関する構造生物学的研究
Papers (9)：
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Sho Amatsu, Kazuki Saito, Shigeru Miyata, Masahiko Zuka, Hirofumi Nariya, Yukako Fujinaga. Development and Optimization of Genetic Manipulation Systems in Group I Clostridium botulinum. bioRxiv. 2024
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Sho Amatsu, Takuhiro Matsumura, Masahiko Zuka, Yukako Fujinaga. Molecular engineering of a minimal E-cadherin inhibitor protein derived from Clostridium botulinum hemagglutinin. Journal of Biological Chemistry. 2023. 299. 3. 102944-102944
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Nobuhide Kobayashi, Kimihiro Abe, Sachiyo Akagi, Mayu Kitamura, Yoshitake Shiraishi, Aki Yamaguchi, Masahiro Yutani, Sho Amatsu, Takuhiro Matsumura, Nobuhiko Nomura, et al. Membrane Vesicles Derived From Clostridium botulinum and Related Clostridial Species Induce Innate Immune Responses via MyD88/TRIF Signaling in vitro. Frontiers in Microbiology. 2022. 13. 720308
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Takuhiro Matsumura, Sho Amatsu, Ryo Misaki, Masahiro Yutani, Anariwa Du, Tomoko Kohda, Kazuhito Fujiyama, Kazuyoshi Ikuta, Yukako Fujinaga. Fully Human Monoclonal Antibodies Effectively Neutralizing Botulinum Neurotoxin Serotype B. Toxins. 2020. 12. 5. 302-302
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Sho Amatsu, Takuhiro Matsumura, Masahiro Yutani, Yukako Fujinaga. Multivalency effects of hemagglutinin component of type B botulinum neurotoxin complex on epithelial barrier disruption. Microbiology and immunology. 2018. 62. 2. 80-89
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MISC (3)：
Patents (1)：
Lectures and oral presentations (38)：
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ボツリヌス菌の遺伝子改変方法の開発
(第96回日本細菌学会総会 2023)
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Endogenous production and neurotoxicity of novel botulinum neurotoxin (BoNT/X) in a clinical isolate
(第96回日本細菌学会総会 2023)
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A型ボツリヌス神経毒素に対するヒト型モノクローナル抗体の開発・解析
(第96回日本細菌学会総会 2023)
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Development of Genetic Manipulation methods for Group I Clostridium botulinum
(58th Intergency Botulism Research Coordinating Committee (IBRCC) meeting 2022 2022)
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腸管ボツリヌス症モデルマウスからのボツリヌス菌検出方法の検討
(第106次日本法医学会学術全国集会 2022)
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Education (2)：
- 2014 - 2018 Osaka university Graduate school of medicine
- 2012 - 2014 Kyoto Institute of Technology Graduate school of Engineering Department of Biomolecular Engineering
Professional career (1)：
- Ph.D. in Medicine (Osaka University)
Work history (2)：
- 2018/06 - 2024/06 Kanazawa university Graduate school of medical sciences Assistant professor
- 2018/04 - 2018/06 Kanazawa university Graduate school of medical sciences Postdoctoral fellow
Committee career (3)：
- 2022/04 - 2025/03 毒素シンポジウム 運営委員
- 2022/04 - 2023/03 金沢大学宝町地区事業場 代議員
- 2021/04 - 2022/03 金沢大学宝町地区事業場 代議員
Awards (4)：
- 2019/04 - Japanese Society for Bacteriology Poster Award Molecular engineering of a minimal derivative from Clostridium botulinum hemagglutinin that inhibits the function of E-cadherin
- 2018/07 - Toxin Symposium Young Scientist Award Molecular engineering of a minimal derivative from Clostridium botulinum hemagglutinin that inhibits the function of E-cadherin
- 2018/03 - Japanese Society for Bacteriology Poster Award Multivalency effect of HA of type B botulinum toxin complex on epithelial barrier disruption
- 2014/06 - Protein Science Society of Japan Poster Award Crystal structure of hemagglutinin from type B Clostridium botulinum
Association Membership(s) (2)：
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